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R. C. Gupta , D. K. Jain

Abstract

Five common Indian species which are used for plywood making were selected to study the role of extractives in the rate of development of bond strength using cold set Urea-formaldehyde resin as glue. Extraction with hot water decreased the failing load from that of control (unextracted) values while extraction with ether, alcohol/benzene improved the bonding strength. Rate of development of bond strength is only slightly effected with the type of extraction carried out and it is maximum in case of ether, alcohol/benzene extraction in most of the cases.

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R. C. Gupta , D. K. Jain

Abstract

Nine different species of timbers both from soft and hardwoods were subjected to different stages of resin treatment and curing as is generally done in the case of plywood etc. After each stage of treatment, the physical strength properties eg. Modulus of elasticity, Modulus of regidity and Tensile strength were evaluated. The results show striking similarity in behaviour with only few exceptions. The presence of moisture and wet resin decidedly decrease the strength properties.

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S. R. D. Guha , D. K. Jain

Abstract

The kinetics or periodate oxidation of Bamboo hemicellulose (Glucuronoxylan) have been studied in aqueous solution at 30°C & pH 4. It is observed that oxidation of hemicellulose follows a first order kinetics with respect to periodate concentration and the rate of oxidation is directly proportional to hemicellulose concentration. In the present studies an attempt to establish the rate law and the probable course of oxidation reaction have been made.

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S. R. D. Guha , Y. K. Sharma , D. K. Jain , Krishna Kumar , B. G. Karira

Abstract

The paper reports the results on sulphate pulping of four soft woods (viz., Larix griffithii, Abies spectabilis, Tsuga durnosa, Picea spinulosa) and two hardwoods (viz., Acer spp., Betula spp,) of Sikkim origin, as well as proximate analysis and fibre dimensions. The lignin content of the softwoods is higher than that of the hardwoods whereas holocelulose is lower as usual. When pulped individually under, identical conditions East Himalayan fir gave the best results amongst softwoods and Birch was found better in the case of hardwoods. Furnish obtained by blending the pulps of individual species and those obtained by cooking the mixture of all the species gave almost similar strength properties. The results have revealed that all these woods are suitable for manufacture of high strength kraft papers.

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N. C. Jain , R. C. Gupta , D. K. Jain

Abstract

no abstract

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S. R. D. Guha , Y. K. Sharma , G. M. Mathur , Rajesh Pant , D. K. Jain

Abstract

The suitability of Pinus kesiya grown in Manipur has been investigated for the production of cable insulation paper. The average fibre length in thls species 2.28 mm and average diameter 0.0399 mm. Under the conditions studied at unbleached yield of 55.6 percent on oven-dry chips the breaking length was 8.22 km and tear factor was 148.5. The paper made on the pilot plant was evaluated for electrical properties. The electrical strength was comparable with imported paper. The conductivity of water extract and ash cOntent of the paper was, however, high. This was due to the hard-water used for the manuracture of paper.

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S. R. D. Guha , Y. K. Sharma , Rajesh S. P. Pant , D. K. Jain , B. G. Karira

Abstract

Results of pulping qualities or Eucalyptus 'hybrid' (Mysore Gum. mostly E. tereticornis) grown in various localities or Uttar Pradesh are recorded. Attempts have also been made to study the effect of age, rate or growth and top, middle and bottom portion of the main bole on pulping qualities. The results indicate that Eucalyptus 'hybrid' grown in Taral and Bhabar Division, Barkot Range, Lachhlwala Range, Bijnor Plantation Division or in Shivalik Range is equally suitable ror pulp and papermaking. There is an indication that up to 9 years of age the strength properties of pulp improves. No significant difference was round in pulp quality when sample for different rate of growth and top, middle and bottom portion were pulped using same pulping conditions.

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R. Patel ¹, D. K. Jain ¹, R. C. Saxena ², M. Bharti ², D. Barve ³, B. K. Dubey ³

Affiliations
1 Dept. of Chemistry, S.S.L. Jain. P.G. College, Vidisha (M.P), IN
2 Ayurvedic Drug Reserch Lab, S.S.L. Jain.P.G. College, Vidisha (M.P), IN
3 TIT College of Pharmacy, Bhopal (M.P), IN

Abstract

Tephrosia purpurea of family Leguminoceae is a shrub distributed in most places throught the country. Preliminary chemical examination shows the presence of flavonoid compound. The crude drug may be of antihistaminic value which is to be established eperimentally. In this research paper preliminary work regarding Tephrosia purpurea has been given such as Percentage yield of crude extract of Tephrosia purpurea by soxhlet extraction method and Thin Layer chromatography/Column Chromatography of 90 % Methanolic extract of plant materials with Rf value and the color characteristics. The work is quite progressive and rest of the work will be submitted in another paper.

Keywords

Tephrosia purpurea, Leguminoceae, Flavonoid, Anti-Histaminic.

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Sunil Singh ¹, Nitin Dubey ¹, D. K. Jain ¹

Affiliations
1 College of Pharmacy, IPS Academy, Rajendar Nagar, Indore [Madhya Pradesh], IN

Abstract

Atorvastatin [R-(R*,R*)]-2-(4-fluorophenyl)-β, δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenyl amino)carbonyl]-1H-pyrrole 1-heptanoic acid an Anti-hyperlipidemia and Clopidogrel (2-Chloro phenyl, 6-7 dihydro4H thieno [3,2-c]pyridine-5-yl)acetic acid is an Anti-platelet drug and Aspirin (2-Acetoxy benzoic acid) an NSAIDs. This paper presents two methods i.e. first derivative spectrophotometery and multicomponent spectrophotometery for simultaneous estimation of these three drugs combination in pharmaceutical formulations. The first derivative amplitudes at 276, 226 and 222 nm were utilized for simultaneous estimations. The multicomponent amplitudes at 247, 220 and 235 nm were utilizatied. Proper selection of wavelength for estimations of one drug by other in derivative spectra and multicomponent lead to successful development of methods for simultaneous estimation. The results of analysis were validated statistically that included parameters such as precision, LOD, LOQ, recovery and robustness. Both methods were simple, economical, accurate, reproducible and precise.

Keywords

Simultaneous Determination, Derivative Spectroscopy, Multicomponent Method.

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Jain Sachin ¹, Jain Neetesh ¹, A. Tiwari ¹, N. Balekar ¹, D. K. Jain ¹

Affiliations
1 College of Pharmacy, IPS Academy, Rajendra Nagar, Indore (M.P.), IN

Abstract

The present study was aim to investigate the possible effect of Ageratum conyzoides ischolar_main extract on wound healing and is also include a comparable study of effect of polyherbal formulation containing Ageratum conyzoides, Ficus religiosa, Curcuma longa and Tamarindus indica, on wound healing process with respect to intact plant formulation through topical route. The wound healing property of Ageratum conyzoides appears to be due to the presence of its active principles, which accelerates the healing process and confers breaking strength to the healed wound. Further, wound healing activity by polyherbal formulation was found to be better than ageratum treated groups in rat. It may be attributed to the synergistic action of ageratum constituent and the constituent of other plants present in the polyherbal formulation.

Keywords

Ageratum conyzoides, Wound Healing.

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Nitin Dubey ¹, Nidhi Dubey ², R. S. Mehta ³, A. K. Saluja ³, D. K. Jain ¹

Affiliations
1 College of Pharmacy, IPS Academy, Indore [M.P], IN
2 School of Pharmacy, Devi Ahilya University, Indore [M.P], IN
3 A R College of Pharmacy, Vallabh Vidyanagar [Gujarat], IN

Abstract

Kushta-e-gaodanti was prepared as per the method mentioned in Unani formulary. The raw materials, intermediates obtained during the preparation of kushta and the final product were characterized using modern analytical techniques like Fourier transform infra-red spectroscopy (FTIR). X-ray powder diffraction (XRPD) and thermo gravimetric analysis (TGA). The study shows that the mineral Gaodanti (calcium sulphate dihydrate) is converted into calcium sulphate hemi hydrate on first calcination in earthen pot sealed with the process gil-e-hikmat. Further on calcination this intermediate is transformed to kushta-e-gaodanti which is orthorhombic α-calcium sulphate anhydride. Kushta-e-gaodanti is a fine powder with particle size 7-8 micrometer, calcium content 29.32%, bulk density 0.928, tapped density 1.268, angle of repose 36.67° and the value of Carr’s index is 47.08. Loss on drying at 110°C and loss on ignition was not more than 0.5 %w/w and 0.05% w/w respectively. Microbial load of the preparation was found negative for the presence of Escherichia coli, Salmonella species and Staphylococcus aureus. Total aerobic count was under acceptance limit. Trace element analysis of bhasma by ICP-OES revealed the presence of some other important metals like arsenic, lead, chromium, cadmium, mercury, tin under acceptable limits at prescribed dose.

Keywords

FTIR, Calcination, Unani Traditional Medicine.

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Ronika Saxena ¹, Poonam Garg ¹, D. K. Jain ²

Affiliations
1 Department of Chemistry, Bareilly College, Bareilly - 243 005, Uttar Pradesh, IN
2 Department of Zoology, Bareilly College, Bareilly - 243 005, Uttar Pradesh, IN

Abstract

An attempt was made to study the antioxidant property of vitamin E in endosulfan and chlorpyrifos toxicity. Erythrocytes were collected from healthy rats and exposed to 1 ppm endosulfan and chlorpyrifos pesticides individually and also along with vitamin E treatment. Results showed that endosulfan was more toxic in comparison of chlorpyrifos. Activities of superoxide dismutase and catalase were significantly decreased, while lipid peroxidation and glutathione-S-transfarase were increased in comparison to the control values. The results of the present study suggest that vitamin E acts as an effective antioxidant for endosulfan and chlorpyrifos pesticide toxicity, in reducing oxidative stress burden.

Keywords

Catalase, chlorphyrifos, endosulfan, erythrocytes, lipid peroxidation, superoxide dismutase, vitamin E

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