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Boopathy, D.
- User Friendly API Based Cloud Database
Authors
1 School of Information Technology & Science, Dr. GR Damodaran College of Science, Coimbatore, Tamilnadu, IN
Source
Data Mining and Knowledge Engineering, Vol 3, No 6 (2011), Pagination: 345-350Abstract
The Paper emphasizes the advantages of Cloud Database Model and the necessity to ensure security level and data loss. In each and every segment of UF-CDB, the data accessing is verified and retrieved by set of tools. The tools are ID Generation tool, ID Verification tool, DB Connector Code generation tool, Database Download tool, Database Upload tool and DB Convertor tool. UF-CDB toolbar synchronizes the user with online database for maximum utility. By using these tools the data are protected in cloud database. In real world, to implement an enterprise server with multiple accessing point may cost very high and in the mean time, it is possible only by very large companies. But the small companies are not able to do the same thing. The UF-CDB provides the enterprise facility to everyone. So the small companies also get the facilities like large companies with minimum cost. The User Friendly Cloud Database also known as UF-CDB.Keywords
Cloud Database, Online Database, API Based Database.- A New RP-HPLC Method for the Simultaneous Estimation of Rabeprazole Sodium and Itopride Hydrochloride in Formulation
Authors
1 Department of Pharmaceutical Analysis, J.K.K. Nattraja College of Pharmacy, Komarapalayam- 638 183, Namakkal (D.T), Tamil Nadu, IN
Source
Asian Journal of Research in Chemistry, Vol 4, No 7 (2011), Pagination: 1077-1080Abstract
A simple, sensitive, precise, accurate, rapid and reproducible reverse phase high performance liquid chromatographic procedure is developed for simultaneous determination of Rabeprazole sodium and Itopride hydrochloride in Capsule dosage form. The mobile phase used was a combination of methanol: buffer (65:35 v/v) and the pH was found to be 4.30. The detection of the capsule dosage form was carried out at 285 nm and the flow rate employed was 1 mL/min. Linearity was obtained in the concentration range of 2.5 to 15 μg/mL of Rabeprazole sodium and 20 to 120 μg/mL of itopride hydrochloride with a correlation coefficient of 0.998 and 0.996 respectively. The results of the analysis were validated statistically and recovery studies confirmed the accuracy of the proposed method.
Keywords
Rabeprazole Sodium(RS), Itopride Hydrochloride(IH), HPLC.- Simultaneous Estimation of Diethylcarbamazine Citrate and Cetirizine Hydrochloride in Formulation by RP-HPLC
Authors
1 Department of Pharmaceutical Analysis, J.K.K. Nattraja College of Pharmacy, Komarapalayam -638 183, Namakkal (DT), Tamil Nadu, IN
Source
Asian Journal of Research in Chemistry, Vol 4, No 7 (2011), Pagination: 1064-1066Abstract
A Simple and reproducible method for simultaneous estimation of Diethylcarbamazine citrate (DECC) and Cetirizine hydrochloride (CTH) by High performance liquid chromatography (HPLC) in formulation was developed. The analysis was performed with a mobile phase containing Acetonitrile and mixed phosphate buffer (KH2PO4 and KH2PO4, adjusted to pH - 3.0 with 10% orthophosphoric acid) in the ratio of 60:40(%v/v) at a flow rate of 1ml/min. A phenomenex C18 column (250 × 4.6mm,5μm)was used. The wavelength of DECC is 216nm and Cetirizine is 230nm and from the overlapping spectra a wavelength of 220nm is selected and simultaneous estimation is carried out .The analysis was performed in the linearity range of 24-144 μg/ml for Diethylcarbamazine citrate and 0.8 - 4.8 μg/ml for Cetirizine hydrochloride and the minimum detectable level was 0.62 μg/ml and 0.105 μg/ml.The correlation coefficient was 0.998 and 0.997.Thus the developed and validated chromatographic method for Diethylcarbamazine citrate and Cetirizine hydrochloride is said to be rapid, simple, accurate and cost effective that can be applied for routine analysis in research institution, quality control department in industries and in clinical pharmacokinetic studies.