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Khobragade, Deepak
- Formulation and in Vivo Evaluation of Oro-Dispersible Tablets of Ayurvedic Powders Sitopaladi and Talisadi
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Authors
Affiliations
1 Vijaya College of Pharmacy, Hyderabad-501 511, Telangana, IN
1 Vijaya College of Pharmacy, Hyderabad-501 511, Telangana, IN
Source
Research Journal of Pharmaceutical Dosage Form and Technology, Vol 8, No 3 (2016), Pagination: 177-180Abstract
Most of the ayurvedic medicines are in the form of powder and they may have some kind of unacceptable or bitter taste and have problem of patient compliance. Medicines in powder form have problem of administration of accurate dose with ease. Furthermore it needs water or honey for administration and chances of spoilage and waste are more. Formulation of Oro-dispersible tablets which rapidly disintegrate in mouth will be the best remedy for efficient use of ayurvedic powders. The aim of this study was to formulate oro-dispersible tablets of ayurvedic polyherbal powder Sitopaladi and Talisadi using various excipients like super-disintegrants and sweeteners and compare the efficacy in vivo using rats. The cough suppressing activities of powder and tablets was evaluated by counting bouts of cough in control group and treated group rats with powders and ODT. Codeine was taken as standard anti-tussive drug for our research. The cough bouts were produced in rats by exposure to SO2 generated by reaction of Na2SO3 and water in a Desiccator. The test results show that there is very little change in the activity of formulated tablets and pure ayurvedic powder. Thus it can be concluded from the study that that formulation of oro-dispersible tablets of ayurvedic powder preparation not only results in improving acceptability, ease and accuracy of administration without affecting efficiency of powder ayurvedic preparations like Talisadi and Sitopaladi.Keywords
Talisadi, Oro-Dispersible, Ayurvedic, Poly-Herbal Powder, Cough.- In Vitro Evaluation of Antioxidant Potential of Ayurvedic Preparations Lauha Bhasma and Mandura Bhasma
Abstract Views :207 |
PDF Views:1
Authors
Affiliations
1 Shri Indu Institute of Pharmacy, Hyderabad, IN
2 Vijaya College of Pharmacy, Hayathnagar, Hyderabad, IN
1 Shri Indu Institute of Pharmacy, Hyderabad, IN
2 Vijaya College of Pharmacy, Hayathnagar, Hyderabad, IN
Source
Asian Journal of Pharmaceutical Research, Vol 7, No 2 (2017), Pagination: 63-66Abstract
The changing environmental conditions and food habits have evoked a great deal of attention toward the study of free radicals. Free radicals are introduced in our body by various endogenous systems, exposure to different physiochemical conditions or some pathological states. Free radicals are exposure to body leads to condition called oxidative stress. When body is unable to manage increased oxidative stress, we need to supply a source of antioxidant to the body. An antioxidant can be broadly defined as a substance inhibits oxidative damage to a target molecule mainly caused by free radicals. Antioxidants are very important in treating many disorders or are used as supportive treatment for various disorders which are caused or aggravated by oxidative stress. Lauha bhasma and Mandura bhasma are well known ayurvedic preparations traditionally used as a haematinic for treating various disorder specially blood disorders. Antioxidants and antioxidant potential are very important in treating many blood disorders and are very supportive in the haematinic action. The present study evaluates the antioxidant potential of Lauha bhasma and Mandura bhasma. The antioxidant activity was evaluated by DPPH scavenging activity and Hydrogen peroxide scavenging activity, Ascorbic acid was used as standard antioxidant agent for comparative evaluation. The results show that both the bhasma have significant antioxidant activity i.e. more than 80% of that of standard ascorbic acid. Mandura bhasm being having comparatively more antioxidant potential than Lauha bhasma.Keywords
Lauha Bhasma, Mandura Bhasma, Ayurvada, Free Radicals, Antioxidant.- In Vitro Evaluation of Antioxidant Potential of N–Acetyl-D-Glucosamine
Abstract Views :232 |
PDF Views:7
Authors
Affiliations
1 Shri Indu Institute of Pharmacy, Hyderabad, IN
2 Vijaya College of Pharmacy, Hayathnagar, Hyderabad, IN
1 Shri Indu Institute of Pharmacy, Hyderabad, IN
2 Vijaya College of Pharmacy, Hayathnagar, Hyderabad, IN