Refine your search
Co-Authors
- M. N. Shubhashree
- S. H. Doddamani
- N. Shiddamallayya
- V. Rama Rao
- B. N. Sridhar
- Bimal Prasanna Mohanty
- D. Karunakaran
- Arabinda Mahanty
- Satabdi Ganguly
- Dipesh Debnath
- Tandrima Mitra
- Sudeshna Banerjee
- Anil Prakash Sharma
- T. V. Sankar
- R. Anandan
- Suseela Mathew
- K. K. Asha
- Kajal Chakraborty
- P. Vijayagopal
- B. N. Paul
- N. Sridhar
- S. Chanda
- Debajit Sarma
- Nityanand Pandey
- Neetu Shahi
- Pushpita Das
- Partha Das
- Md. Shahbaz Akhtar
- J. Syama Dayal
- K. K. Vijayan
- S. Kannappan
- S. D. Singh
- Madan Mohan
- B. Meenakumari
- S. Ayyappan
- S. Swathi
- B. Swathi
- Kasireddy Swapna
- N. Sharada
- P. Laxmi
- M. Prathapa Reddy
- T. R. Shantha
- M. Seethamma
- B. Vijayakumar
- G. Sai Prasad
- M. Chennaiah
- T. Veeraiah
- K. Susmitha
- K. Radha
- T. Sai Prasad
- K. Damodar Reddy
- Sayaji Rao
- T. Charan Singh
- Ravinder Burugu
- Jagjitsingh C. Girase
- Saurabh Kumar Banerjee
Journals
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All
Venkateshwarlu, G.
- Therapeutic and Nutritional Values of Narikelodaka (Tender Coconut Water) - A Review
Abstract Views :393 |
PDF Views:2
Authors
Affiliations
1 National Ayurveda Dietetics Research Institute (NADRI), Govt. Central Pharmacy Annexe Near Ashoka Pillar, Jayanagar, Bangalore, Karnataka, IN
1 National Ayurveda Dietetics Research Institute (NADRI), Govt. Central Pharmacy Annexe Near Ashoka Pillar, Jayanagar, Bangalore, Karnataka, IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 6, No 4 (2014), Pagination: 195-201Abstract
Background: Tender coconut water is a wholesome and nutritious drink. It has an important role to play in the fastdeveloping functional foods market particularly nutraceuticals and pharmaceuticals. The resurgence of interest in the coconut generated due to the awareness of people about the possible hazards from soft drinks and the promotional measures taken by government have contributed to the growth of market for tender coconut water. Value - added products presents an opportunity for intensifying and building on past research and development work. Coconut water is one of the world's most versatile natural product with increasing scientific evidence that support the role of coconut water in health and medicinal application. Medicinally, it has been proven to possess various pharmacological activities like hepatoprotective, anti-inflammatory, antipyretic, wound healing, anti thrombotic, antioxidant, Hypolipidaemic, Antihypertensive, diuretic, hypoglycemic, renal regenerative actions. Over the past decades, many reports have appeared in mainstream scientific journals describing its nutritional and medicinal properties. Glimpse of the classical Ayurvedic texts gives us an insight into the medicinal properties of coconut that is in tune with the scientific findings of today. This review attempts to reiterate and appraise the therapeutic and nutritional values of coconut water.Keywords
Tender Coconut Water, Narikelodaka, Coconut Juice, Ayurveda, Nutrition.
References
- Verma V., Bhardwaj A., Rathi S. et al, A Potential Antimicrobial Agent from Cocos nucifera mesocarp extract, Development of a New Generation Antibiotic, ISCA Journal of Biological Sciences Vol. 1(2), 48-54, June (2012).
- P. Rethinam, Coconut for nutrition, Health and Healing Traditional and medicinal uses. Indian Coconut Journal. Vol LII No.8, Dec 2009, Pg 2.
- Khan. M. Nasiruddin, M.U. Rehman and K.W. Khurram. (2003), A study of chemical composition of Cocos nucifera L. (Coconut) water and its usefulness as rehyderation fluid. Pak. J. Bot. 35(5): 925-930.
- P.V. Sharma, Fruits and Vegetables in ancient India, Chaukambha orientalia 2009 First Edition Page 53.
- http://www.ceylonkokonati.com/the_coconutstory_1.php
- Alexia Prades, et al, Coconut water uses, composition and properties: a review, Fruits, 2012, 67, 87-107.
- Nisaudah R et al Young coconut juice significantly reduces histopathological changes in the brain that is induced by hormonal imbalance: A possible implication to postmenopausal women. Histol. Histopathol., 2009; 24: 667-674.
- Chowdhury MGF, et al, Processing and Preservation of Green Coconut Water. J Innov Dev Strategy. 2009;2(3):01-05.
- S. Sankaranarayanan, Folk-Lore Medicines For Jaundice From Coimbatore And Palghat Districts Of Tamil Nadu and Kerala, India.Ancient Science of Life, Vol No. VII Nos. 3 and 4,January-April 1988, Pages175-179.
- Heritage Amruth, Medplan Conservatory Society, Bangalore, Vol.5,issue 6, Nov-Dec.2009, Page 26.
- Sushruta, Sushruta Samhita,Vol I (Edited with Ayurveda Tattva Sandipika) by Shastri Kaviraja Ambikadutta, 12th ed. Varanasi: Chaukhamba Sanskrit Sansthan 2001,Sutrasthana, 42/12, Page 228.
- Bhavamishra. Bhavaprakasha Nighantu-Hindi Commentary by K.C. Chunekar., Chaukhumbha Bharathi Academy; 2002, Amraphaladi varga 41st shloka pg-558-559.
- Gyanendra Pandey, Dravyaguna Vignana, Vol-2, Choukambha Krishnadas Academy, Varanasi 2004 page 673-681.
- Anonymous, Indian medicinal plants, Compendium of 500 species, Vol 2,Orient Longman Pvt Ltd, Chennai.
- Sahasrayoga, Mahendrapalasiha Arya, Vamaya Anusandhana Ekaka, Kendriya Ayurveda eva Siddha Anusandhana Pariad, 1990 Urdhwanga Roga Chikitsa (Netraroga) Page 52.
- Kaviraja Sen Govinda Das, Bhaishajya rathnavali with Siddhiprabha Hindi commentary by Prof. Mishra Siddhinandan, 1st Ed, Varanasi; Choukambha Surabharathi Prakashana, Reprint 2007, Sula Rogadhikara 168-169 pg.464.
- Vaidya Shastry Lakshmipathy, Yogarathnakara with Vidyotini Hindi commentary, 2nd Ed, Varanasi; Choukambha Sanskrit Pratishtana, Reprint 2007; pg.504.
- Agnivesha. Charaka samhita-Agnivesha treatise refined and annoted by Charaka, redacted by Dridhabala Ayurveda Deepika commentary by Chakrapanidatta, edited by Yadavji Trikamji Acharya. Varanasi: Chaukhamba Prakashana; reprint 2011, pg 738.
- Damodar Joshi ,V. Nagaraju, Study on the concept on sodhana with special Reference to Visopavisas, Ancient Science of Life, Vol No. VII Nos. 3 and 4, January and April 1988, Pages 195-200.
- Ibe CC, CN Osuji, EU Nwabueze and EO Ahaotu, 2013. Chemical composition of coconut water. Inter J Agri Biosci, 2(5): 185-187.
- Reni Mullukattil Lukose The Chemical Composition of Tender Coconut (Cocos nucifera L.) Water and Coconut Meat and Their Biological Effect in Human Body. International Journal of Green and Herbal Chemistry (IJGHC), June 2013-August 2013; Vol.2, No.3; 723-729.
- Maimuna Waziri, Abdulrahman A. Audu and Fanika Suleiman, Analysis of Some Mineral Elements in Major Coconut Cultivars in Nigeria. Journal of Natural Sciences Research. Vol.3, No.8, 2013.
- Anonymous, Wealth of India, Council of Scientific and Industrial Research,1950,Raw materials Vol 2, Pg 277-278.
- Joao L.A. Santos et al, Evaluation of Chemical Constituents and Antioxidant Activity of Coconut Water (Cocus nucifera L.) and Caffeic Acid in Cell Culture (Annals of the Brazilian Academy of Sciences) (2013) 85(4) 1235-1246.
- Wealth of Ayurvedic Medicinal Plants of Mandya District, Karnataka
Abstract Views :186 |
PDF Views:0
Authors
Affiliations
1 National Ayurveda Dietetics Research Institute, GCP Annexe, Ashoka Pillar, Jayanagar, Bangalore, Karnataka, IN
1 National Ayurveda Dietetics Research Institute, GCP Annexe, Ashoka Pillar, Jayanagar, Bangalore, Karnataka, IN
Source
Indian Forester, Vol 141, No 1 (2015), Pagination: 83-98Abstract
In Karnataka state, Western Ghats are playing a major role in the supply of raw plant material to pharmaceutical industry. Mandya district is having an unique geograhical nature which is supportive for Ayurvedic medicinal plant resources for the growth of pharmaceutical industry. A total of 89 Ayurvedic medicinal plants were enlisted from Mandya, along with list of Ayurvedic formulations. As per selected medicinal plants demand study, of enlisted Ayurvedic medicinal plants, 28 plants are identified as demanding plants for the preparations of herbal and Ayurvedic system of medicine. Of recorded 16 medicinal plants are collected from tropical forests, 16 from wastelands and 08 from cultivation practice. These are considered as high traded medicinal plants for the pharmaceutical industry in India.Keywords
Forest, Medicinal Plants, Ayurveda, Pharmacy.- Database on Nutritional Composition of Food Fishes from India
Abstract Views :270 |
PDF Views:97
Authors
Bimal Prasanna Mohanty
1,
D. Karunakaran
1,
Arabinda Mahanty
1,
Satabdi Ganguly
1,
Dipesh Debnath
1,
Tandrima Mitra
1,
Sudeshna Banerjee
1,
Anil Prakash Sharma
1,
T. V. Sankar
2,
R. Anandan
2,
Suseela Mathew
2,
K. K. Asha
2,
Kajal Chakraborty
3,
P. Vijayagopal
3,
B. N. Paul
4,
N. Sridhar
4,
S. Chanda
4,
Debajit Sarma
5,
Nityanand Pandey
5,
Neetu Shahi
5,
Pushpita Das
5,
Partha Das
5,
Md. Shahbaz Akhtar
5,
J. Syama Dayal
6,
K. K. Vijayan
6,
S. Kannappan
6,
G. Venkateshwarlu
7,
S. D. Singh
8,
Madan Mohan
8,
B. Meenakumari
8,
S. Ayyappan
9
Affiliations
1 ICAR-Central Inland Fisheries Research Institute, Barrackpore, Kolkata 700 120, IN
2 ICAR-Central Institute of Fisheries Technology, Cochin 682 029, IN
3 ICAR-Central Marine Fisheries Research Institute, Cochin 682 018, IN
4 ICAR-Central Institute of Freshwater Aquaculture, Bhubhaneswar 751 002, IN
5 ICAR-Directorate of Coldwater Fisheries Research, Bhimtal 263 136, IN
6 ICAR-Central Institute of Brackishwater Aquaculture, Chennai 600 028, IN
7 ICAR-Central Institute of Fisheries Education, Mumbai 400 061, IN
8 ICAR-Fisheries Science Division, Krishi Anusandhan Bhawan II, Pusa, New Delhi 110 012, IN
9 Krishi Bhavan, Indian Council of Agricultural Research, New Delhi 110 012, IN
1 ICAR-Central Inland Fisheries Research Institute, Barrackpore, Kolkata 700 120, IN
2 ICAR-Central Institute of Fisheries Technology, Cochin 682 029, IN
3 ICAR-Central Marine Fisheries Research Institute, Cochin 682 018, IN
4 ICAR-Central Institute of Freshwater Aquaculture, Bhubhaneswar 751 002, IN
5 ICAR-Directorate of Coldwater Fisheries Research, Bhimtal 263 136, IN
6 ICAR-Central Institute of Brackishwater Aquaculture, Chennai 600 028, IN
7 ICAR-Central Institute of Fisheries Education, Mumbai 400 061, IN
8 ICAR-Fisheries Science Division, Krishi Anusandhan Bhawan II, Pusa, New Delhi 110 012, IN
9 Krishi Bhavan, Indian Council of Agricultural Research, New Delhi 110 012, IN
Source
Current Science, Vol 109, No 11 (2015), Pagination: 1915-1917Abstract
No Abstract.Full Text
- Changes of Life Style Prevent Heart Stroke, Kidney Failure, Paralysis
Abstract Views :186 |
PDF Views:0
Authors
S. Swathi
1,
B. Swathi
2,
Kasireddy Swapna
1,
G. Venkateshwarlu
1,
B. Swathi
2,
N. Sharada
1,
P. Laxmi
1
Affiliations
1 Venkateshwara Institute of Pharmaceutical Sciences, Cherlapally, Nalgonda, Telangana, IN
2 Department of Pharmacy, Palamuru University, Mahabubnagar, Telangana, IN
1 Venkateshwara Institute of Pharmaceutical Sciences, Cherlapally, Nalgonda, Telangana, IN
2 Department of Pharmacy, Palamuru University, Mahabubnagar, Telangana, IN
Source
Asian Journal of Pharmaceutical Research, Vol 5, No 1 (2015), Pagination: 48-50Abstract
Now a day's peoples are completely habituated for cool life or without hard work so this reason causes many diseases. Recently most of the software employees yield for spondilysis, gastritis, heart stroke, brain stroke and paralysis etc. especially throughout world youth suffering with stress condition and money earning pressure and restless work, mechanical life also causes various diseases. Recently in Nalgonda one survey held on brain stroke and kidney failure, paralysis. In that survey as a pharmacist and other doctors are conducted for every 100 persons participated in that 7 members are heart stroke, 5 persons are kidney failure, 3 are paralyzed persons are there. This survey carried at Government hospital, Gollguda, Nalgonda, Telangana. why this ailments are raising means lack of exercise, fast food eating, environmental pollution, restless life, insomnia, companies task pressure on employ along with lot of reasons are there.Keywords
Heart Stroke, Kidney Failure, Paralysis, Disease Survey.- Pharmacognostical and Physicochemical Evaluation on the Flowers of Justicia adhatoda L.
Abstract Views :167 |
PDF Views:0
Authors
Affiliations
1 National Ayurveda Dietetics Research Institute, Ashoka Pillar, Jayanagar, Bangalore-560011, IN
1 National Ayurveda Dietetics Research Institute, Ashoka Pillar, Jayanagar, Bangalore-560011, IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 7, No 2 (2015), Pagination: 73-90Abstract
The present communication attempts to evaluate the macroscopy, microscopy, physico-chemical, preliminary phytochemical and Thin Layer Chromatography (TLC) fingerprint studies of different extracts on the flowers of Justicia adhatoda L. (Adhatoda zeylanica Medicus, A. vasica Nees). Microscopical studies revealed that flowers possess abundant uniseriate, biseriate and multiseriate elongated trichomes, glandular trichomes with bicelled heads, cystoliths in calyx region, light brown tannin content, papillae like out growth, and well developed spongy and palisade parenchyma in corolla region. Preliminary phytochemical screening of the extracts showed the presence of alkaloids, carbohydrates, flavonoides, phenols, proteins, saponins and tannins. These parameters will be useful in the identification and standardization of the flower drug of Vasa and also to identify other species of Adhatoda.
Keywords
Vasa, Pharmacognosy, Adhatoda, Phytochemical, Macroscopy, Microscopy.- Pharmacognostic and Physicochemical Evaluation of the Different Varieties of Sesamum indicum L. – A Comparative Study
Abstract Views :149 |
PDF Views:0
Authors
Affiliations
1 National Ayurveda Dietetics Research Institute, Ashoka Pillar, Jayanagar, Bangalore-560011, IN
1 National Ayurveda Dietetics Research Institute, Ashoka Pillar, Jayanagar, Bangalore-560011, IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 6, No 2 (2014), Pagination: 99-106Abstract
Sesame is a condiment which is used in every household for culinary, religious and medicinal purposes. The present study deals with pharmacognostical and physicochemical evaluation of different varieties (black, white and brown) of Sesame (Sesamum indicum Linn.). The study revealed that the different varieties of Sesame seeds, microscopically shows all most similar characters, however, distribution of oil globules varies only in the case of black variety seeds. Oil globules and reddish contents are more in case of white variety when compared to other brown and black. Comparative study has taken up to identify the different varieties of Sesame with respect to its macroscopy, microscopy and other parameters like physico-chemical, preliminary phytochemical, fluorescence and TLC studies.Keywords
Sesame, Varieties of Sesame, Pharmacognosy, Thin Layer Chromatography.- Extractive Spectrophotometric Methods for Determination of Esmolol Hydrochloride Using Acidic Triphenylmethane Dyes
Abstract Views :170 |
PDF Views:0
Authors
Affiliations
1 Department of Chemistry, Nizam College (O.U), Hyderabad, 500001, IN
1 Department of Chemistry, Nizam College (O.U), Hyderabad, 500001, IN
Source
Asian Journal of Research in Chemistry, Vol 4, No 11 (2011), Pagination: 1789-1792Abstract
Three simple and sensitive extractive spectrophotometric methods have been described for the assay of Esmolol hydrochloride either in pure form or in pharmaceutical formulations. The developed methods involve formation of coloured chloroform extractable ion-pair complexes of the drug with bromothymol blue (BTB), bromophenol blue (BPB) and bromocresol green (BCG) in acidic medium. The extracted complexes showed absorbances maxima at 415,412 and 412nm with BTB, BPB and BCG respectively. Beer's law is obeyed in the concentration ranges 2.5- 25μg/ml for all three dyes. The effect of concentration of dye and pH have been studied and optimized. The limits of detection and quantification have been determined for three methods. All the three methods have been validated as per the guidelines of ICH. The methods have been applied to the determination of drug in commercial tablets and results of analysis were validated statistically through recovery studies.Keywords
Esmolol Hydrochloride, Bromothymol Blue, Bromophenol Blue, Bromocresol Green, Spectrophotometry.- Extractive Spectrophotometric Methods for Determination of Ambroxol Hydrochloride in Pharmaceutical Formulations Using Some Acidic Triphenylmethane Dyes
Abstract Views :188 |
PDF Views:0
Authors
Affiliations
1 Department of Chemistry, Nizam College, Hyderabad, 500001, IN
2 Department of Chemistry, SAP College Vikarabad, Ranga Reddy, Andhra Pradesh, 501101, IN
1 Department of Chemistry, Nizam College, Hyderabad, 500001, IN
2 Department of Chemistry, SAP College Vikarabad, Ranga Reddy, Andhra Pradesh, 501101, IN
Source
Asian Journal of Research in Chemistry, Vol 4, No 7 (2011), Pagination: 1109-1113Abstract
Three simple and sensitive extractive spectrophotometric methods have been described for the assay of Ambroxol hydrochloride either in pure form or in pharmaceutical formulations. The developed methods involve formation of coloured chloroform extractable ion-pair complexes of the drug with bromothymol blue (BTB), bromophenol blue (BPB) and bromocresol purple (BCP) in acidic medium. The extracted complexes showed absorbance maxima at 414, 412 and 407nm with use of the cited reagents, respectively. Beer's law is obeyed in the concentration ranges 2.5-25, 4.0-30 and 4.0-40μg/ml with BTB, BPB and BCP respectively. The effect of concentration of dye, pH, and interference of excipients have been studied and optimized. The limits of detection and quantification have been determined for three methods. All the three methods have been validated as per the guidelines of ICH. The methods have been applied to the determination of drug in commercial tablets and results of analysis were validated statistically through recovery studies.
Keywords
Ambroxol Hydrochloride, Bromothymol Blue, Bromophenol Blue, Bromocresol Purple, Spectrophotometry.- Extractive Spectrophotometric Methods for Determination of Tamsulosin HCl in Pharmaceutical Formulations Using Acidic Triphenyl Methane Dyes
Abstract Views :193 |
PDF Views:0
Authors
Affiliations
1 Department of Chemistry, St. Anns College for Women, Hyderabad -500028, A.P., IN
2 Department of Chemistry, Nizam College, Hyderabad -500001, A.P., IN
1 Department of Chemistry, St. Anns College for Women, Hyderabad -500028, A.P., IN
2 Department of Chemistry, Nizam College, Hyderabad -500001, A.P., IN
Source
Asian Journal of Research in Chemistry, Vol 4, No 7 (2011), Pagination: 1114-1118Abstract
Four simple and sensitive extractive spectrophotometric methods have been described for the assay of Tamsulosin hydrochloride either in pure form or in pharmaceutical formulations. The developed methods involve formation of colored chloroform extractable ion-pair complexes of the drug with bromothymol blue (BTB), bromophenol blue (BPB), bromocresol purple (BCP) and bromocresol green (BCG) in acidic medium. The extracted complexes showed absorbance maxima at 415 nm for all four methods. Beer's law is obeyed in the concentration ranges 2.5-25, 2.5-25, 2.0 - 25 and 2.5 - 25. μg/ml with BTB, BPB, BCP and BCG, respectively. The effect of concentration of dye, pH, and interference of excipients have been studied and optimized. The limits of detection and quantification have been determined for four methods. All the four methods have been validated as per the guidelines of ICH. The methods have been applied to the determination of drug in commercial tablets and results of analysis were validated statistically through recovery studies.
Keywords
Tamsulosin Hydrochloride, Bromothymol Blue, Bromophenol Blue, Bromocresol Green, Bromocresol Purple, Spectrophotometry.- Extractive Spectrophotometric Methods for Determination of Moxifloxacin Hydrochloride Using Acidic Triphenylmethane Dyes
Abstract Views :161 |
PDF Views:0
Authors
Affiliations
1 Department of Chemistry, Nizam College (O.U), Hyderabad, 500001, IN
1 Department of Chemistry, Nizam College (O.U), Hyderabad, 500001, IN
Source
Asian Journal of Research in Chemistry, Vol 4, No 8 (2011), Pagination: 1297-1301Abstract
Three simple and sensitive extractive spectrophotometric methods have been described for the assay of Moxifloxacin hydrochloride either in pure form or in pharmaceutical formulations. The developed methods involve formation of coloured chloroform extractable ion-pair complexes of the drug with bromothymol blue (BTB), bromophenol blue (BPB) and bromocresol green (BCP) in acidic medium. The extracted complexes showed absorbances maxima at 415,416 and 417nm with BTB, BPB and BCG respectively. Beer's law is obeyed in the concentration ranges 2.5-25μg/ml for all three dyes. The effect of concentration of dye, pH, and interference of excipients have been studied and optimized. The limits of detection and quantification have been determined for three methods. All the three methods have been validated as per the guidelines of ICH. The methods have been applied to the determination of drug in commercial tablets and results of analysis were validated statistically through recovery studies.Keywords
Moxifloxacin Hydrochloride, Bromothymol Blue, Bromophenol Blue, Bromocresol Green, Spectrophotometry.- Spectrophotometric Determination of Drugs Using p-Chloranilic Acid as Analytical Reagent
Abstract Views :162 |
PDF Views:0
Authors
Affiliations
1 Department of Chemistry, Nizam College, Hyderabad, 500 001, IN
1 Department of Chemistry, Nizam College, Hyderabad, 500 001, IN
Source
Asian Journal of Research in Chemistry, Vol 4, No 8 (2011), Pagination: 1311-1317Abstract
Six drugs viz., Metoprolol tartrate, Torsemide, Diclofenac sodium, Chlorpheniramine, Loratadine and irbesartan were tested for the formation of charge transfer complexes with p-CA and the interaction formed a basis for quantitative determination of the drugs spectrophotometrically. CH3CN was found to be suitable for the analysis. The methods have been validated in terms of ICH guidelunes The complexes were found to have 1:1 composition and have stability of the order 105.Keywords
Spectrophotometry, p-CA, Drug, Quantification, Validation.- Extractive Spectrophotometric Methods for Determination of Pioglitazone Hydrochloride Using Acidic Triphenylmethane Dyes
Abstract Views :191 |
PDF Views:0
Authors
Affiliations
1 Department of Chemistry, Nizam College (O.U), Hyderabad, 500001, IN
2 Department of Chemistry, SAP College, Vikarabad, Ranga Reddy, A P, 501101, IN
1 Department of Chemistry, Nizam College (O.U), Hyderabad, 500001, IN
2 Department of Chemistry, SAP College, Vikarabad, Ranga Reddy, A P, 501101, IN
Source
Asian Journal of Research in Chemistry, Vol 4, No 6 (2011), Pagination: 971-975Abstract
Three simple and sensitive extractive spectrophotometric methods have been described for the assay of Pioglitazone hydrochloride either in pure form or in pharmaceutical formulations. The developed methods involve formation of coloured chloroform extractable ion-pair complexes of the drug with bromothymol blue (BTB), bromophenol blue (BPB) and bromocresol purple (BCP) in acidic medium. The extracted complexes showed absorbance maxima at 415 nm for all three methods. Beer's law is obeyed in the concentration ranges 2.0-30, 3.0-30 and 2.5-25μg/ml with BTB, BPB and BCP respectively. The effect of concentration of dye, pH, and interference of excipients have been studied and optimized. The limits of detection and quantification have been determined for three methods. All the three methods have been validated as per the guidelines of ICH. The methods have been applied to the determination of drug in commercial tablets and results of analysis were validated statistically through recovery studies.Keywords
Pioglitazone Hydrochloride, Bromothymol Blue, Bromophenol Blue, Bromocresol Purple, Spectrophotometry.- RP-HPLC Determination of Amlodipine Besylate and Atorvastatin in Amlodipine Besilate and Atorvastatin Tablets
Abstract Views :126 |
PDF Views:0
Authors
Source
Asian Journal of Research in Chemistry, Vol 3, No 3 (2010), Pagination: 763-766Abstract
A simple, specific, accurate and precise high performance liquid chromatographic method was developed for the determination of Amlodipine and Atorvastatin in Amlodipine besylate and Atorvastatin tablet dosage forms. A Hypersil BDS C18 5 μm (250×4.6 mm I.D) with column temperature 30°C in isocratic mode, with mobile phase containing Acetonitrile:10 mM Ammonium acetate buffer pH 4.0 (50:50) was used. The flow rate was 1.0 mL/min and effluent was monitored at 238 nm.The retention time of Amlodipine was 2.5 min and for Atorvastatin was 4.7 min. The linearity for Amlodipine and Atorvastatin was in the range 0.02 mg/mL to 0.12 mg/mL. The proposed method is accurate, precise, specific and rapid estimation of Amlodipine and Atorvastatin in Amlodipine besilate and Atorvastatin tablets.Keywords
HPLC, Amlodipine Besylate (AMD), Atorvastatin (ATVR), Dissolution, Assay, Validation, Isocratic Elution.- Development and Validation of RP-HPLC Method for Simultaneous Determination of Ceftriaxone Sodium and Sulbactam Sodium in Bulk and Pharmaceutical Formulation
Abstract Views :187 |
PDF Views:0
Authors
Affiliations
1 School of Pharmacy Technology and Management, SVKM’s, NMIMS University, Shirpur Campus, Babulde, Near Bank of Tapi River, Shirpur-425405, Dist Dhule (M.S), IN
2 Research and Development Division, Concept Pharmaceuticals Ltd, Aurangabad, IN
1 School of Pharmacy Technology and Management, SVKM’s, NMIMS University, Shirpur Campus, Babulde, Near Bank of Tapi River, Shirpur-425405, Dist Dhule (M.S), IN
2 Research and Development Division, Concept Pharmaceuticals Ltd, Aurangabad, IN