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Singhvi, Indrajeet
- Novel Colorimetric Methods for Quantitative Estimation of Diacerin from Capsule Formulation
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Authors
Affiliations
1 PRIST University, Thanjavur, Tamilnadu, IN
2 Pacific College of Pharmacy, Debari, Udaipur (Rajasthan) 313003, IN
3 P.Wadhwani College of Pharmacy, Yavatmal, Maharahtra, IN
1 PRIST University, Thanjavur, Tamilnadu, IN
2 Pacific College of Pharmacy, Debari, Udaipur (Rajasthan) 313003, IN
3 P.Wadhwani College of Pharmacy, Yavatmal, Maharahtra, IN
Source
Asian Journal of Pharmaceutical Analysis, Vol 3, No 2 (2013), Pagination: 44-47Abstract
Two simple and sensitive colorimetric methods have been developed for the quantitative estimation of Diacerin from Pharmaceutical Capsule dosage form. Developed methods are based on the formation of chloroform extractable ion pair coloured complex of drug with Orange II (Method A) and Tropoelin (Method B). The complex formed in method A and B showed maximum absorbance at 435. Linearity was obeyed in concentration range of 50-350 μgm/ml and 50-250 μgm/ml of Diacerin for method A and B respectively. The results of analysis were validated statistically and by recovery studies.Keywords
Diacerin, Orange II, Tropoelin, Colorimetric Method
References
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- Antisecretory and Antiulcer Activity of Cartaeva nurvala against Indomethacin plus Pyloric Ligation Induced Gastric Ulcers in Rats
Abstract Views :339 |
PDF Views:2
Authors
Affiliations
1 Pacific College of Pharmacy, Pacific Hills, Airpoart Road, Pratapnagar Extension, Udaipur, Rajasthan, 313001, IN
1 Pacific College of Pharmacy, Pacific Hills, Airpoart Road, Pratapnagar Extension, Udaipur, Rajasthan, 313001, IN
Source
Research Journal of Pharmacology and Pharmacodynamics, Vol 3, No 5 (2011), Pagination: 256-259Abstract
Aims: To study the anti-secretory and anti-ulcer activity of Cartaeva nurvala(ethanolic extract) and its action against indomethacin plus pyloric ligation induced gastric ulcers in rats.Settings and Design: Rats treated with two oral doses of indomethacin suspension as a standard dose, at an interval of fifteen hours, two hours after the second dose of indomethacin, Pyloric ligation was carried the rats were destroyed by over-dose of anesthetic ether. Pyloric ligation was done only to collect the gastric content for analysis.
Methods and Material: Indomethacin plus pyloric ligation (PL) induced gastric ulceration model was used in the study.
Statistical analysis used: The results were expressed as mean ± SEM. The significance of difference between mean values for the various treatments was tested using the unpaired student 't' test P<0.05 was considered statistically significant.
Results: Treatment from Cartaeva nurvala crude extract for fifteen days significantly reduced ulcer index when compared with control group. Crude extract also significantly reduced volume of gastric secretion, free acidity and total acidity. A significant increase in total carbohydrate (TC) and TC/total protein (TP) ratio of gastric juice was also observed. No significant change in the total protein was noted.
Conclusions: Cartaeva nurvala was found to be an effective anti-ulcerogenic agent, whose activity can well be compared with that of ranitidine hydrochloride.
Keywords
Anti-Ulcer Activity, Cartaeva nurvala, Indomethacin Plus PL.References
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- Novel Method for Quantitative Estimation of Telmisartan from Tablet formulation by Colorimetric Method
Abstract Views :335 |
PDF Views:0
Authors
Sanjay Bais
1,
Chakravarti Singh
1,
Indrajeet Singhvi
1,
Yash Joshi
1,
Bhaumik Patel
1,
Anil Chandewar
2
Affiliations
1 Pacific College of Pharmacy, Debari, Udaipur, Rajasthan, 313024, IN
2 P. Wadhwani College of Pharmacy, Yavatmal, Maharashtra, 445001, IN
1 Pacific College of Pharmacy, Debari, Udaipur, Rajasthan, 313024, IN
2 P. Wadhwani College of Pharmacy, Yavatmal, Maharashtra, 445001, IN
Source
Asian Journal of Pharmaceutical Analysis, Vol 4, No 2 (2014), Pagination: 54-56Abstract
A simple and sensitive colorimetric method have been developed for the quantitative estimation of Telmisartan from Pharmaceutical Capsule dosage form. Developed method is based on the formation of chloroform extractable ion pair coloured complex of drug with Azurin-B dye. The complex formed in method showed maximum absorbance at 508.00 nm. Linearity was obeyed in concentration range of 4-25 μgm/ml of Telmisartan for method. The results of analysis were validated statistically and by recovery studies.Keywords
Telmisartan, Azurin-B, Colorimetric Method.- U.V. Method for Quantitative Estimation of Diacerein from Capsule Formulation
Abstract Views :379 |
PDF Views:0
Authors
Affiliations
1 Pacific College of Pharmacy, Debari, Udaipur (Rajasthan) -313003, IN
1 Pacific College of Pharmacy, Debari, Udaipur (Rajasthan) -313003, IN