- S. Newale
- T. Fegade
- K. Lakhani
- D. Makwana
- A. Shah
- N. Purohit
- V. Mori
- H. Zadafiya
- M. Hada
- N. Bhalani
- S. Goswami
- R. Patel
- D. Vala
- A. Vadhera
- H. Chapadia
- C. Chapadia
- R. Chauhan
- M. N. Rangani
- D. A. Trivedi
- A. Vadher
- M. K. Singh
- N. L. Selokar
- S. Chand
- S. S. Lathwal
- T. K. Mohanty
- M. S. Chauhan
- S. Chand
- R. Verma
- G. Tripathi
- R. Meena
- Ajay Aswal
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All
Patel, K.
- A Cross-sectional, Multi-Centric, Non-Interventional Study to Understand the Management Practices of Major Depressive Disorder in India (DMI: Depression Management in India)
Authors
1 Clinical Operations, Abbott Healthcare Private Ltd, First Floor, D Mart Building, Mulund-Goregaon Link Road, Mulund West, Mumbai-400080, IN
2 Clinical Operations, Abbott Healthcare Private Ltd, IN
Source
The Indian Practitioner, Vol 68, No 8 (2015), Pagination: 31-39Abstract
Objective: To study clinical presentation of patients with depression and management practices for major depressive disorder (MDD) by healthcare practitioners (HCPs) in India.Material and Methods: In a multi-centre, cross-sectional registry, healthcare practitioners opined about the clinical presentation of patients with depression and management practices for MDD. Physician's opinion on the efficacy and tolerability of antidepressants was graded on a four-point rating scale (1 = Excellent, 2 = Good, 3 = Average and 4 = Poor) and adverse events were recorded.
Results: Data of 1048 patients with mean age of 42.83 years (n = 1048; M:F ratio 7:3) was analysed. Comorbid medical illness in the form of cardiovascular disease, diabetes, osteoarthritis and musculoskeletal diseases were present in 40.60%, 8.15%, 6.18% and 4.99% patients respectively, while alcohol consumption/substance abuse and smoking history was present in 14.72% and 12.75% patients respectively. Depressed mood most of the day (69.65%) was the most common clinical presentation. Counselling was most commonly (50.48%) practiced non-pharmacological treatment by HCPs. In the pharmacological management, selective serotonin reuptake inhibitors (SSRIs) (73.56%) were the most commonly prescribed medicines. Escitalopram was preferred as monotherapy in 78.04% patients and rated to have "good to excellent" efficacy and tolerability in 99.45% patients. Dizziness, sexual dysfunction, nausea, sedation and insomnia were reported in 4.96%, 2.29%, 1.72%, 1.15%, 1.05% patients respectively.
Conclusion: Many patients with depression have co-morbid medical illnesses. SSRIs are the most commonly prescribed antidepressants for the management of depression. Most of the patients are treated with monotherapy and escitalopram is the preferred monotherapy in most patients with depression.
Keywords
Depression, India, Management Practices.
- Delayed Peripheral Neuropathy Due to Organophosphate Tri-Ortho-Cresyl Phosphate Poisoning
Authors
1 Department of Medicine, B J Medical College, Ahmedabad, IN
Source
The Indian Practitioner, Vol 69, No 6 (2016), Pagination: 52-54Abstract
Introduction: 15 patients were admitted to Civil Hospital, Ahmedabad with complains of cramping pain and weakness in bilateral lower limbs. They were found to be suffering from subacute motor neuropathy.
Material And Methods: All were investigated for abnormalities in complete haemogram, blood biochemistry, B12 levels, nerve conduction studies and cholinesterase levels. Results: There was distal muscle weakness in bilateral lower limbs with loss of deep tendon reflexes in lower limbs with EMG suggestive of axonal and demyelinating neuropathy with reduced RBC cholinesterase levels. Discussion: From history and investigations it was found that the ingestion of wheat contaminated with tri-ortho-cresyl phosphate (TOCP) lead to axonal and demyelinating type of polyneuropathy.
Keywords
Delayed Neuropathy, Tri-Ortho-Cresyl Phosphate.References
- Susser M, Stein Z. An outbreak of tri ortho-cresyl-phosphate poisoning in Durban. BMJ. 1957;14(2):111-120.
- Cavanagh JB. Toxic effect of TOCP on nervous system. NCBI. 1954 17:163-172.
- Smith HV, Spalding JMK. Outbreak of paralysis in morocco due to ortho cresyl phosphate poisoining- The Lancet. 1960;2(7110):1019-1021.
- Vij S, Kanagasuntheram R. Effect of tri ortho cresyl phosphate poisoining on sensory nerve terminations of slow loris. Acta neuropathologica. 1972;20(2):150-159.
- Jokanovic M, Kosanovic M, Brkic D, Vukomanovic P. Organophosphate induced delayed polyneuropathy in man- Clinical Neurology and Neurosurgery. 2011;113(1):7-10.
- Bischoff A. Ultrastructure of tri-ortho-cresyl phosphate poisoning in the chicken. Acta neuropathologica. 1970;15:142155 .
- Inoue N, Fujishiro K, Mori K, Matsuoka M. Tri-ortho-cresyl phosphate poisoning- a review of human cases. J UOEH. 1988;10(4):433-42.
- Earl CJ, Thompson RHS. Cholinesterase levels in the nervous system in tri-ortho-cresyl phosphate poisoning. Brit. J. Pharmacol. 1952;7:685.
- Recurrent Episode of Priapism due to Quetiapine in a Bipolar Patient
Authors
1 Griffin Memorial Hospital, Oklahoma, US
2 North Penn Cardiovascular Institute, US
3 Medical College, Baroda, IN
4 Chapadia Medical Center, IN
5 Miller School of Medicine, Miami, US
Source
The Indian Practitioner, Vol 69, No 7 (2016), Pagination: 45-46Abstract
Priapism is a rare side effect of anti-psychotics. Both typical and atypical anti-psychotics can cause priapism. Priapism means persistent and most of the times painful penile erection not associated with sexual stimulation. Priapism can cause urinary retention, cavernosa fibrosis, gangrene and even impotency if it is not treated properly in time. About 50% of priapism patients end up having impotency1. Drugs account for 25-40% of priapism2. The most common drugs causing priapism are anti-hypertensives and anti-psychotics1.
In anti-psychotics, second generation anti-psychotics are more associated with priapism. But the information in the literature is limited. Most common anti-psychotics causing priapism are Risperidone, Olanzapine and Quetiapine. We are reporting a case of recurrent episode of priapism due to Quetiapine use.
Keywords
Priapism, Bipolar Disorder, Anti-Psychotics.References
- Thompson JW, Jr, Ware MR, Blashfield RK. Psychotropic medication and priapism: a comprehensive review. J Clin Psychiatry. 1990;51(10):430–433
- Penaskovic, Kenan M., Fasiha Haq, and Shakeel Raza. “Priapism During Treatment With Olanzapine, Quetiapine, and Risperidone in a Patient With Schizophrenia: A Case Report.” Primary Care Companion to The Journal of Clinical Psychiatry 12.5 (2010): PCC.09l00939. PMC. Web. 29 Mar. 2016.
- Jackson JC, Torrence CL. Quetiapine-induced Priapism Requiring Frequent Emergency Admissions: A Case Report. Urology Case Reports. 2015;3(1):1-2. doi:10.1016/j.eucr.2014.09.003.
- M.J. Geraci, S.L. McCoy, P.M. Crum, et al. Anti-psychoticinduced priapism in an HIV patient: a cytochrome P450mediated drug interaction Int J Emerg Med, 3 (2010), pp. 81–84.
- Study of Dengue Fever with Outcome Analysis in Patients with Normal and Abnormal Liver Function Tests
Authors
1 GMERS Medical College and Hospital, Sola, IN
2 Department of Medicine, GMERS Medical College and Hospital, Sola, IN
Source
The Indian Practitioner, Vol 69, No 9 (2016), Pagination: 11-16Abstract
Background: Study of 100 cases of dengue fever with comparison of outcome in patients with abnormal liver function test v/s normal liver function test.
Methods: An observational and analytical study conducted in GMERS medical college and hospital sola Ahmadabad. 100 adult age 18-75 years patients were included in time period of April, 2014 to April, 2015. Cases of Dengue fever were taken for study presenting with two or more symptoms of dengue fever and positive serology. Routine investigations, liver function tests and ultrasonography of abdomen were carried out. Measurement of outcome with regards to complication, mortality and Length of stay were studied.
Results: Out of 100 patients 60 were Classical DF, 31 DHF and 9 were of DSS. Fever was the most common and Nausea and vomiting was the next common complaint. Significant percentage of Epistaxis and Bleeding were observed in DHF (48.4%) group of patients. Average total bilirubin at presentation was markedly elevated in DSS (2.02±1.38) in comparison to DHF (1.28±1.02) and Classical DF (0.84±1.00) (P<0.05). Average SGPT at presentation was observed to be significantly higher in DSS group (351.38±402.75) followed by DHF (120.56±95.20) and Classical DF (95.40±66.55) group. The difference was statistically significant (P<0.05). Average peak APTT observed to be higher in DSS (44.8±8.2) group followed by DHF (42.2±13.0) and Classical DF (39.6±9.4). SGOT at presentation and the peak value of SGOT with bleeding episodes was observed to be statistically significant. The average length of hospital stay was 5 days. Correlation between average SGOT and average length of stay in the groups with Classical DF and DSS was statistically significant (P<0.05).
Conclusion: Altered liver function test in dengue infection has got effect in terms of length of stay and complications as compared to normal or mild alteration of liver function test. Therefore high SGOT and SGPT can be considered as a prognostic marker of outcome in dengue infection.
Keywords
Dengue Fever, Liver Function, Outcome, Length of Stay, Mortality.References
- Shukla V, Chandra A, A study of hepatic dysfunction in Dengue, JAPI, july2013, vol61. 1-3.
- World Health Organization, Dengue- guidelines for diagnosis, treatment, prevention and control. New Edition, Geneva: World Health Organization Publishers; 2009. p. 4-6.
- George R: LLCS. Clinical spectrum of dengue infection. Washington Cab International; 1997, 3-5
- de Souza LJ, Goncalves Carneiro H, Souto Filho JT, Ferreira de Souza T, Azevedo Cortes V, Neto CG, Bastos DA, da Silva Siqueira EW: Hepatitis in dengue shock syndrome. Braz J Infect Dis 2002, 6(6):322-7.
- Kalayanarooj S, Vaughn DW, Nimmannitya S, Green S, Suntayakorn S, Kunentrasai N, Viramitrachai W, Ratanachu-eke S, Kiatpolpoj S, Innis BL, Rothman AL, Nisalak A, Ennis FA: Early clinical and laboratory indicators of acute dengue illness. J Infect Dis 1997, 176(2):313-21.
- de Souza LJ, Nogueira RM, Soares LC, Soares CE, Ribas BF, Alves FP, Vieira FR, Pessanha FE: The impact of dengue on liver function as evaluated by aminotransferase levels. Braz J Infect Dis 2007, 11(4):407-10.
- Patel LR , Sero prevalence of Dengue NS-1 Antigen in Tertiary care hospital, Ahmadabad , Indian Journal of Basic & Applied Medical Research; June 2013: 7, (2), P. 694-701.
- Kishore J., Singh J., Dhole T.N., and Ayyagari A., Clinical and Serological Study of First Large Epidemic of Dengue in and around Lucknow, India, in 2003 Dengue Bulletin – Volume 30, 2006.
- Chaturvedi UC., and Nagar R., Dengue and dengue Hemorrhagic fever: Indian perspective; J. Biosci. 2008,429–441.
- Sharma S, Sharma SK, Mohan A, Wadhwa J, Dar L, Thulkar S, et al. Clinical profile of dengue Hemorrhagic fever in adults during 1996-outbreak in Delhi, India. Dengue Bull 1998;22:20-27 WHO-SEARO).
- Muhammad A., Khazindar AM., Lubbad EH., Barlas S, Alfi AY., Ukayli AS., Characteristics of Dengue Fever in a Large Public Hospital, Jeddah, Saudi Arabia. J Ayub Med Coll Abbottabad 2006;18(2).
- Itha S., Kashyap R., Krishnani N, Vivek A. Saraswat, Choudhuri G, Aggarwal R. The National Medical Journal Of India Vol. 18, NO. 3, 2005.
- Farid Uddin A., Chowdhury B., Mahmood J., Sharma JD, Hoque M., Zaman R., and ShameemHasan M.,Dengue and Dengue Hemorrhagic Fever in Children During the 2000 Outbreak in Chittagong, Bangladesh.Dengue Bulletin – Vol 25, 2001.
- Uchadadia S, Ghodke B, Bhuta K,Kejriwal A, Ghanekar J. Degree of Impairment of Liver Function in Dengue Fever Correlates to the Severity of its Complications, MGM J Med Sci 2015;2(3):115-119.
- Parkash et al., Severity of acute hepatitis and its outcome in patients with dengue fever in a tertiary care hospital Karachi, Pakistan (South Asia) BMC Gastroenterology 2010, 10:43
- Souza, L.J., Alves, J.G., Nogueira, R.M.R., Neto, C.G., Bastos, D.A., da Siva Siqueira, E.W., SoutoFilho, J.T.D., Cezario, T.A., Soares, C.E., Carneiro, R.C., 2004.
- Khan, E., Kisat, M., Khan, N., Nasir, A., Ayub, S., &Hasan;, R. (2010). Demographic and clinical features of dengue fever in Pakistan from 2003–2007: A retrospective cross-sectional study. PLoS One, 5, e12505.
- Shah I., Dengue and liver disease. Scand J Infect Dis 2008, 40(11-12):993-4.
- Atypical Antipsychotic-Induced Temporomandibular Joint Dislocation
Authors
1 Miller School of Medicine, Miami, US
2 North Shore University, US
3 North Penn cardiovascular Institute, US
4 Medical College, Baroda, IN
5 Chapadia Medical Center, IN
Source
The Indian Practitioner, Vol 69, No 9 (2016), Pagination: 28-29Abstract
Dystonia is a kind of movement disorder that leads to prolonged muscle contractions, leading to abnormal postures of the trunk, neck, face, arms or legs. It can be generalised or focal and primary or secondary depending on the etiology. It can manifest as oculogyric crisis, abnormal tongue movements, torticollis and opisthotonus. Laryngeal and pharyngeal spasms may as well be life threatening. Drug induced dystonia is most commonly caused by the drugs which alter the dopaminergic and cholinergic balance in the nigrostriatum (basal ganglia). Most of these drugs cause dystonia by blocking D2 dopaminergic receptors in the nigrostriatum which leads to an unopposed and unbalanced cholinergic output. Antipsychotics along with metoclopramide are the most common drugs which are responsible for the various dystonias and a common presentation in the psychiatric wards.Keywords
Risperidone, Dystonia, Dislocation.References
- O’Hara VS. Extrapyramidal reactions in patients receiving prochlorperazine. N Engl J Med. 1958;259(17):826-828. PubMed doi:10.1056/NEJM195810232591707
- Singh H, Levinson DF, Simpson GM, et al. Acute dystonia during fixed-dose neuroleptic treatment. J Clin Psychopharmacol. 1990;10(6):389–396. PubMed doi:10.1097/00004714-199010060-00002
- [Zones, 2006; Mendhekar et al. 2009; Das et al. 2008; Jhanjee and Gupta, 2009; Sankhla et al. 1998].
- Levine M, Burns MJ. Antipsychotic agent. In: Shannon MW, Borron SW, Burns MJ, editors. Haddad and Winchester’s Clinical Management of Poisoning and Drug Overdose. 4th ed. Philadelphia, PA: Saunders Elsevier; 2007. p. 703-20.
- Sankhla C, Lai EC, Jankovic J. Peripherally induced oromandibular dystonia. J Neurol Neurosurg Psychiatry 1998;65(5):722-8.
- Buffalo calves from the semen of cloned bulls
Authors
1 Embryo Biotechnology Lab, Animal Biotechnology Centre, ICAR-National Dairy Research Institute, Karnal 132 001, India
Source
Current Science, Vol 123, No 3 (2022), Pagination: 253-253Abstract
No Abstract.Full Text
- Ganga: India’s First Cloned Cow that belongs to Indigenous Gir Breed
Authors
1 ICAR-National Dairy Research Institute, Karnal 132 001, IN
2 Uttarakhand Livestock Development Board, Dehradun 248 001, IN
Source
Current Science, Vol 125, No 1 (2023), Pagination: 10-10Abstract
No Abstract.Keywords
No Keywords.Full Text
References
- Basic Animal Husbandry Statistics, Department of Animal Husbandry, Dairying and Fisheries (DADF) of India, 2022; http://dahd.nic.in
- Selokar et al., 2018; https://doi.org/10.1089/cell.2017.0051.
- National Dairy Plan, Department of Animal Husbandry, Dairying and Fisheries (DADF) of India; http://dahd.nic.in