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Prashanth, K.
- Teaching Programme Promotes Awareness on IMNCI [Integrated Management of Neonatal and Child Hood Illness] among Trained Nurses
Abstract Views :176 |
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Authors
Anu Rani A. Augustine
1,
P. Mohammed Siraj
1,
K. Prashanth
1,
Shomiya Shaju
1,
G. S. Shilpa
1,
J. Uma Rani
1
Affiliations
1 Department of Child Health Nursing, Yenepoya Nursing College, Yenepoya University, Derelakatte, Mangalore, 575018, Karnataka, IN
1 Department of Child Health Nursing, Yenepoya Nursing College, Yenepoya University, Derelakatte, Mangalore, 575018, Karnataka, IN
Source
International Journal of Advances in Nursing Management, Vol 2, No 2 (2014), Pagination: 79-81Abstract
Integrated management of neonatal and child hood illness is very essential for effective management of children during illness. The aim of the study was to determine the effectiveness of teaching programme on knowledge regarding IMNCI among trained nurses. The research design selected for the study was quasi experimental pre test post test design. Thirty Five Trained nurses were considered as sample for the study. Convenience sampling technique was used for sample selection. The instrument used for the study was self administered structured knowledge questionnaire. The planned teaching programme was administered soon after pre-testing. Then the post test was conducted after one week. The findings revealed that the mean post test knowledge score was significantly higher than that of pre test score. The calculated 't' value (11.86) was greater than the table value at 0.05 level significance. The study concluded that teaching programme on IMNCI was effective in imparting knowledge among the trained nurses.Keywords
IMNCI (Integrated Management of Neonatal and Child Hood Illness), Trained Nurses, Knowledge.
- Hepato-Protective Studies of Poloxamer – 188 by Paracetomol Induced Liver Toxicity in Rats
Abstract Views :162 |
PDF Views:0
Authors
T. Arif Hussain
1,
M. D. Imad Uddin
2,
M. D. Irfan Uddin
1,
M. D. Nadeem
1,
H. Talha
1,
K. Prashanth
1
Affiliations
1 Dept. of Pharmacology, MAK College of Pharmacy, Moinabad, Hyderabad, Telanagana, 501504, IN
2 Dept. of Pharmacology, Pulla Reddy Institute of Pharmacy, Sangareddy, Hyderabad, Telanagana 502313, IN
1 Dept. of Pharmacology, MAK College of Pharmacy, Moinabad, Hyderabad, Telanagana, 501504, IN
2 Dept. of Pharmacology, Pulla Reddy Institute of Pharmacy, Sangareddy, Hyderabad, Telanagana 502313, IN
Source
Research Journal of Pharmacy and Technology, Vol 12, No 2 (2019), Pagination: 574-578Abstract
Poloxamer-188 (P-188) is a polymer well renowned for possessing medical properties. Present study was conducted with an aim to evaluate Hepato-protective potential of P-188 against paracetamol induced liver damage in wistar albino rats. Group-I served as Normal control which received normal saline 5ml/kg of Body weight (BW) for 7 days. Group-II served as Negative control in which animals received same dose as mentioned in Group-I. Group-III, IV and V animals received P-188(50mg/kg), P-188(100mg/kg) and silymarin (25mg/kg) respectively for 7 days. Except Group-I all other groups challenged with a very high dose of paracetamol (750 mg/kg) to induce hepatotoxicity. Biochemical estimation results showed that SGOT, SGPT and ALP levels were increased in negative control group animals which were decreased to normal levels when treated with P-188. There was highly significant (p<0.0001) decrease of these values in all three treatment groups. Moreover decrease in P-188 treated groups is dose dependent. Histopathological study supports the results of biochemical estimation. Negative control animal showed inflammation with mild cholestasis. P-188 (50mg/kg) showed mild inflammation, more number of normal hepatocytes, whereas P-188 (100 mg/kg) showed scattered lymphocytes among normal hepatocytes and kupffer cell hyperplasia, no incidence of inflammation and necrosis. Based on these results we can conclude that P-188 is a hepatoprotective polymer.Keywords
Poloxamer-188, Paracetamol, Hepato-Protective, Silymarin, Histopathological Study.References
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