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Sekar, M.
- Transposable Elements:Strategies and Mechanism of Transposition in Danio rerio, a Genetic Model
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Authors
Dharmendra Kumar Meena
1,
B. K. Behera
1,
Pronob Das
1,
A. K. Prusty
2,
Satendra Kumar
3,
M. Sekar
3,
Kanti Meena
4
Affiliations
1 Central Inland Fisheries Research Institute (CIFRI), Barrackpore, Kolkata (W.B.), IN
2 Project Directorate of Farming System Research, Meerut (U.P.), IN
3 Central Institute of Fisheries Education, Mumbai (M.S.), IN
4 Central Research Institute for Jute and Allied Fibres, Barrackpore, Kolkata (W.B.), IN
1 Central Inland Fisheries Research Institute (CIFRI), Barrackpore, Kolkata (W.B.), IN
2 Project Directorate of Farming System Research, Meerut (U.P.), IN
3 Central Institute of Fisheries Education, Mumbai (M.S.), IN
4 Central Research Institute for Jute and Allied Fibres, Barrackpore, Kolkata (W.B.), IN
Source
Asian Journal of Bio Science, Vol 7, No 2 (2012), Pagination: 223-229Abstract
Zebra fish (Danio rerio) is an excellent model animal to study vertebrate development by various genetic approaches. External development and transparent nature of its embryo makes it feasible to visualize and manipulate a cell in the living organism. Genetic engineering is well suitable in this organism due to the availability and easy collection of large number of embryos from the adult fish. Several approaches have been implemented to manipulation the zebra fish at DNA, RNA and protein level by employing different technologies (EMU and trapping based mutagenesis, TILLING, site specific recombination, transgenics and so on). Identification of several transposon in this model organism has opened the doors for genetic manipulation with a new approach which can be effectively used in other animals. Taking these into consideration it can be used in transgenic development which would increase sustainability by manifolds in term of production and vigour traits production. This study highlight the recent developments in the field of insertional mutagenesis in zebra fish, the mechanisms and concepts of new transposon-based mutagenesis approaches under development which may be used as reference approach for adopting in commercially important fish or gene silencing for disease diagnosis in higher vertebrates . This review is an eye opening signal for researcher which would ignite deep interest to carry forward these modern tools and techniques to address the short falls of genetic improvement strategies indispensable for sustainable aquaculture.Keywords
Zebra Fish, (Danio rerio), Transposones, Mutagenesis, Genetic Model, Gene Trapping.- A Multi-Criteria Decision Making Model for Rapid Prototyping Supply Chain
Abstract Views :179 |
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This paper deals with the selection of a suitable RP process based on multiple attribute decision making system that best suits the end use of a part. Evaluation factors include only major attributes that significantly affect the performance of an RP system such as accuracy, roughness, strength, part cost, material. The major attributes are identified as falling within approximate ranges due to many variable parameters.
This paper proposes a methodology that is based on Analytic Hierarchy Process (AHP). This methodology offers a simple, systematic and logical procedure for decision making. By this methodology, each attribute's relative weight is assigned using a pair wise comparison matrix. With these relative weights, the final ranking order aids in the selection of RP process. C language is used to store, edit and update RP process characteristic database and also to Implement this methodology. The methodology presents supply chain integration on an inter business relationship. The proposed system act as a virtual consultant between the RP process industries and manufacturing industries taking into account of benefits of both the manufacturing industries and end user. Thus this system strengthens the supply chain.
Authors
M. Sekar
1,
E. Manavalan
1
Affiliations
1 Government College of Technology, Coimbatore-13, IN
1 Government College of Technology, Coimbatore-13, IN
Source
Manufacturing Technology Today, Vol 4, No 11 (2005), Pagination: 20-22Abstract
Rapid prototyping (RP), an emerging technology that fabricates a three dimensional physical model from CAD data using an additive process. RP has been developed to reduce product development time and cost. Recently, a number of RP techniques along with different machine models are available to produce the prototype. Each model has specific characteristics in terms of accuracy, strength, roughness, cost, material, etc. With these characteristics. It becomes difficult to choose most suitable RP process for manufacturers.This paper deals with the selection of a suitable RP process based on multiple attribute decision making system that best suits the end use of a part. Evaluation factors include only major attributes that significantly affect the performance of an RP system such as accuracy, roughness, strength, part cost, material. The major attributes are identified as falling within approximate ranges due to many variable parameters.
This paper proposes a methodology that is based on Analytic Hierarchy Process (AHP). This methodology offers a simple, systematic and logical procedure for decision making. By this methodology, each attribute's relative weight is assigned using a pair wise comparison matrix. With these relative weights, the final ranking order aids in the selection of RP process. C language is used to store, edit and update RP process characteristic database and also to Implement this methodology. The methodology presents supply chain integration on an inter business relationship. The proposed system act as a virtual consultant between the RP process industries and manufacturing industries taking into account of benefits of both the manufacturing industries and end user. Thus this system strengthens the supply chain.