Informatics Publishing Limited

Kaliberdenko V.B. ¹, Kuznetsov E.S. ², Morozova M.N. ³, Malev A.L. ⁴, Zakharova A.N. ⁵, Shanmugaraj K. ⁶, Balasundaram K. ⁶

Affiliations
1 Associate Professor, Department of Internal Medicine No.2, V.I. Vernadsky Crimean Federal University, Simferopol, RU
2 Assistant Professor, Department of Internal Medicine No.1, V.I. Vernadsky Crimean Federal University, Simferopol, RU
3 Professor, Department of Dentistry and Orthodontics, V.I. Vernadsky Crimean Federal University, Simferopol, RU
4 Associate Professor, Department of Psychiatry, Narcology, Psychotherapy with a Course of General and Medical Psychology, V.I. Vernadsky Crimean Federal University, Simferopol, RU
5 Associate Professor, Department of Internal Medicine No.1, V.I. Vernadsky Crimean Federal University, Simferopol, RU
6 Department of Internal Medicine No.2, V.I. Vernadsky Crimean Federal University, Simferopol, RU

Abstract

The efficacy of using probiotic preparations of the yogurt type was studied in 136 patients with lymphogranulomatosis, suffering from intestinal dysbiosis while taking antibiotic therapy and polychemotherapy (BEACOPP‑II protocol). It was found that probiotics of this type are highly effective for the treatment of dysbiotic disorders of the intestines in cancer and hematological patients. Their use significantly reduces the risk of complications such as an unpleasant aftertaste in the mouth, belching, heartburn, diarrhea, constipation, flatulence, discomfort or periodic abdominal pain. It is recommended that prolonged therapy with a probiotic of the yogurt type be used in these groups of patients.

Keywords

Probiotic, dysbiosis, eubiosis, dyspepsia, lymphogranulomatosis, polychemotherapy.

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