Informatics Publishing Limited

Neha Meshram ¹, Mithlesh Ojha ¹, Ajay Singh ², Amit Alexander ¹, Ajazuddin ¹, Mukesh Sharma ¹

Affiliations
1 Rungta College of Pharmaceutical Sciences and Research, Kohka, Kurud, Bhilai C.G., IN
2 G D Rungta College of Science and Technology, Kohka, Kurud, Bhilai C.G., IN

Abstract

Kusum or Sagade (Schleichera oleosa) is well known tree of medicinal importance in India. All parts of Kusum are used in Indian Traditional Healing. The Traditional Healers use Kusum in simple as well as complex herbal formulations. Kusum based Herbal Formulations are popular among the Healers of present generation but it is really surprising that very few Kusum based Formulations are available in Global Drug Market as promising products. Schleichera trijuga Wild), is a tropical plant prevalent in Orissa and other parts of India (foliage: deciduous, and semi evergreen). That is locally called as "Kusum" (Hindi) and "Kusuma" (Oriya). It belongs to Family "Sapindaceae". Fruiting season is usually in the monsoon. Fruits are simple, fleshy and of 'Berry' category which is either one seeded or two seeded Kusum oil' is a novel substance that has been used by tribal people for their disease like, cold, itch, ulcer for both human and cattle. It was confirmed after the discussion with native inhabitants in the area where the "Kusum' fruits were collected. Studies have also described the medicinal use of the 'Kusum Oil' which is traditionally used for the cure of itch, acne, burns, other skin troubles, rheumatism (external massage), hair dressing and promoting hair growth. Powdered seeds of Schleichera trijuga are used for ulcers and wounds of cattle to remove maggots and bark is used for skin imflammations and ulcers. The chemical composition of Schleichera trijuga seeds has been investigated by column chromatographic, ultraviolet and infrared spectrophotometrie methods. Schleichera oleosa, belonging to the Sapindaceae family, has been reported to possess antimicrobial, antioxidant, anticancer activity, and can be used for the production of biodiesel. The plant contains low tannin levels therefore it can be used as fodder for livestock. This species contains important phytochemicals such as terpenoids, betulin, betulinic acid etc. The literature reveals that this medicinal plant can be used as an alternative to synthetic compounds for use in preventing and treating several diseases. Considering the medicinal and environmental uses of this plant, this review is an effort to summarize nearly all the information reported on its various activities.

Keywords

Rheumatism, Column Chromatography, Livestock.

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Neha Meshram Ojha ¹, Mithlesh Ojha ¹, Ajay Singh ², Amit Alexander ¹, Ajazuddin ¹, Mukesh Sharma ¹

Affiliations
1 Rungta College of pharmaceutical sciences and research Kohka-Kurud, Bhilai, C.G, IN
2 GD Rungta College of Science and Technology Kohka-Kurud, Bhilai, C.G, IN

Abstract

Peptic ulcer disease is an imbalance between offensive and defensive gastric factors. This is a major cause of mortality in developing countries. This has attracted several scientists foe their research contributions to this area. Peptic ulcer disease is a serious gastrointestinal disorder that requires a well targeted therapeutic strategy. A number of drugs including proton pump inhibitors and H2 receptor antagonists are available for the treatment of peptic ulcer, but clinical evaluation of these drugs has shown incidence of relapses, side effects and drug interactions. This has been the rational for the development of new antiulcer drugs and the novel formulations that extend to herbal drugs. Good scientific confirmation of traditional knowledge of drugs for treatment of various disorders has made herbal approach a scientific budding area of interest now days. This review article includes physiological aspects of peptic ulcer disease and list of herbal drugs which are used in the treatment of peptic ulcer. Here we have highlighted some of the important plants reported for their anti-ulcer and ulcer healing properties. Ayurvedic knowledge supported by modern science is necessary to isolate, characterise, and standardise the active constituents from herbal sources for antiulcer activity.

Keywords

Peptic Ulcer, Traditional Knowledge, Gastrointestinal Disorder, Novel Formulations, Drug Interactions.

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Mithlesh Ojha ¹, Neha Meshram ¹, Ajay Singh ², Amit Alexander ¹, Ajazuddin ¹, Mukesh Sharma ¹

Affiliations
1 Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud, Bhilai, C.G., IN
2 GD Rungta College of Science and Technology Kohka-Kurud, Bhilai, C.G., IN

Abstract

Medicinal plants are part and parcel of human society to combat diseases, from the dawn of civilization. Information about the benefits of herbal drugs is known in our ancient literature of Ayurvedic, Siddha, Unani and Chinese medicine. According to the WHO, 2003 about 80 % of the population of developing countries being unable to afford pharmaceutical drugs relies on traditional medicines, mainly plant based, to sustain their primary health care needs. The consequences of this long neglect of developing acceptable and reliable male contraceptives in poor developing countries has been lack of or less participation of males in family planning. Recently, it has come apparent that neglecting men in matters of family planning is a losing strategy with adverse consequences for both men and women Ayurvedic literature and folk medicine have been screened and searched thoroughly for antifertility effects in males all over the world. The World Health Organization has set up a task force on plant research for fertility regulation with an objective to find new orally active non steroidal contraceptive. Therefore, this article reviewed some of the medicinal plants having antifertility or contraceptive activity. This review will highlight some of the herbs which could potentially be developed into a reversible male contraceptive as well as discuss difficulties of developing such a contraceptive.

Keywords

Medicinal Plants, Health Care, Antifertility Effects, Non Steroidal Contraceptive, Male Antiinfertility.

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