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Authors
Affiliations
1 Pranveer Singh Institute of Technology, Bhauti, Kanpur-208020, (U.P), IN
2 Jamiya Hamdard University, New Delhi, IN
Source
Asian Journal of Research in Chemistry, Vol 3, No 1 (2010), Pagination: 22-25
Abstract
A new series of NSAID’S in which aspirin is joined by ester linkage to pyrrole-2-carboxylic acid were synthesized and tested for anti-platelet activity. Related propyl esters of aspirin and aspirin as such were taken as references. All the compounds described here show anti-platelet activity but they do not behave as prodrugs of aspirin in blood serum.
Keywords
NSAID’S, Aspirin, Anti-Platelet Agents, Pyrrole.