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Patel, Nikhil
- Recent Advances in Transdermal Drug Delivery System
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1 Department of Pharmaceutics and Pharmaceutical Technology, Shri Sarvajanik Pharmacy College, Near Arvind Baug, Mehsana-384 001, IN
1 Department of Pharmaceutics and Pharmaceutical Technology, Shri Sarvajanik Pharmacy College, Near Arvind Baug, Mehsana-384 001, IN
Source
Research Journal of Pharmaceutical Dosage Form and Technology, Vol 2, No 2 (2010), Pagination: 113-119Abstract
Human skin serves a protective function by imposing physicochemical limitations. For a drug to be delivered passively via the skin it needs to have a suitable lipophilicity and a molecular weight < 500 Da. The number of commercially available products based on transdermal or dermal delivery has been limited by these requirements. In recent years various passive and active strategies have emerged to optimize delivery. The passive approach entails the optimization of formulation or drug carrying vehicle to increase skin permeability. However, passive methods do not greatly improve the permeation of drugs with molecular weights >500 Da. In contrast, active methods, normally involving physical or mechanical methods of enhancing delivery, have been shown to be generally superior. The delivery of drugs of differing lipophilicity and molecular weight, including proteins, peptides and oligonucletides, has been shown to be improved by active methods such as iontophoresis, electroporation, mechanical perturbation and other energy-related techniques such as ultrasound and needleless injection.Keywords
Techniques For Transdermal Delivery, Microneedle, Radiofrequency Drug Delivery System, Iontophoresis.- A Study to Assess the Effectiveness of Structured Teaching Programme (STP) on Knowledge Regarding Risk Factors and Prevention of Peptic Ulcer among the Middle Age Population in Selected Urban Area at Mehsana City
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1 Joitiba College of Nursing, Bhandu, Dist: Mehsana, IN
1 Joitiba College of Nursing, Bhandu, Dist: Mehsana, IN
Source
Asian Journal of Nursing Education and Research, Vol 9, No 3 (2019), Pagination: 370-372Abstract
Background : Peptic ulcer is an excavation or hole that forms in the mucosal wall of the stomach, in the pylorus, in the duodenum and in the esophagus. A peptic ulcer is frequently referred to as gastric, duodenal or esophageal ulcer depending on its location or as peptic ulcer disease.1 Aims and Objective: To assess the knowledge regarding risk factors and prevention of peptic ulcer among the middle age population in selected area at Mehsana city. To assess the effectiveness of structured teaching programme on risk factors and prevention of peptic ulcer among the middle age population in selected area at Mehsana city. To find out the association of the knowledge with their selected demographic variables. Methods- a quantitative approach using pre experimental one group pre test -post test design. 100 people were selected using non probability convenience sampling in Mehsana city. Structure teaching programme was given to the people residing in Mehsana city. Self structure questionnaire will prepare and used to assess the knowledge. Results: in this study overall the highest percentage in the demographic data including the age group 45-50 were 27%, gender male is 64%, religion Hindu is 64%, marital status married 89%, family type joint is 59%, education status primary is 44%, occupation other is 39%, monthly income 10001-15000 is 37%, sample has any bed habits in that no 67%, Bed habits yes in that 43% is smoking, samples chronic illness diabetes is 40%. Out of 100 pre-test samples poor knowledge is 81%, adequate 19% and good 0%. Post-test poor knowledge is 3%, adequate 59% and good 38%. The pre-test knowledge means score is 6.72 and standard deviation is 2.35. Post test knowledge score is 12.89 and standard deviation 3.78. The âTâ test calculated value is 34.4 and table âTâ test table value is 1.98 which is significant at 0.05 levels. Thus it rejects the null hypothesis and accepts the research hypothesis. The pre test and post test mean % is 26.88% and 51.56% and different is 24.68%.so knowledge is increase after intervention. This indicates that the structure teaching programme is effective in increasing the knowledge regarding risk factor and prevention of peptic ulcer. Chi-square test to associate the level of knowledge and selected demographic variable.Keywords
Assess, Effectiveness, Structure Teaching Programme, Knowledge, Risk Factor, Prevention, Middle Age, People, Peptic Ulcer and Urban Area.References
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