A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All
Kale, Niraj
- Overview of Nutraceuticals
Authors
1 GES’s Satara College of Pharmacy, Degaon, Satara 415004 (M.S.), IN
Source
Asian Journal of Pharmaceutical Research, Vol 12, No 1 (2022), Pagination: 61 - 70Abstract
The word or term “Nutraceutical” is a combination of two words i.e. “Nutrition” and “Pharmaceutical”. The term 'nutraceutical' was coined in 1989 by DeFelice. Basically nutraceutical is a food or part of food and it has huge historical background regarding to treatment of various disease. Nutraceuticals plays a significant role in normal physiological function, which helps to maintain human health. In recent period, all people are conscious about their daily diet as well as health. In India many people have preconception or prejudice about nutrition and health. India is a developing country. So many people of rural areas are suffering from non-communicable diseases and disorders due to lack of proper knowledge about nutrition, food and diet. The present article provides some information about “Nutraceuticals and human health. In recent years there is a growing interest in nutraceuticals has been seen in market place. This article mainly helps to provide essential knowledge of nutraceutical with its numerous uses in various ailments. This article also contains important legal requirements that are necessary for register a nutraceutical product.
Keywords
Nutraceutical, Veterinary Nutraceuticals, Ailments, Health, Food Sources, RegulationReferences
- Rajasekaran, A., Sivagnanam, G. and Xavier, R., Nutraceuticals as therapeutic agents: A Review. J. Pharm. Sci. Technol.2008; 1.
- A Review on Nutraceuticals: Classification and ITS Role in Various Diseases Garima V erma; International Journal of Pharmacy and Therapeutics. 2016; 7(4): 152-160
- Jagtar Singh; Classification, Regulatory acts and Applications OF Nutraceuticals for Health; IJPBS. 2012; 2(1): 177-187
- Krishan Kumar. Role of nutraceuticals in health and disease prevention: A review. South Asian J. Food Technol. Environ. 2015; 1(2): 116-121.
- Chan, M. Supporting the integration and modernization of traditional medicine. Science. 2014; 346: S2.
- Zeisel SH. Regulation of Nutraceuticals. Science. 1999; 285:185-186.
- Bhawna Verma and Harvinder Popli. Regulations of nutraceuticals in India and us. The Pharma Innovation Journal. 2018; 7(7): 811-816
- Palthur MP, Palthur SS, Chitta SK. Nutraceuticals: a conceptual definition. Int. J Pharmacy Pharm Sci. 2010; 2(3): 19-27
- Sapkale Anita P. Nutraceuticals - Global status and applications: a Review. International Journal of Pharmaceutical and Chemical Sciences. 2012; 1 (3).
- Kalra, E. K., Nutraceutical-definition and introduction. AAPS Pharm. Sci. 2003; 5: 2-3.
- Chintale Ashwini G. Role of Nutraceuticals in Various Diseases: A Comprehensive Review. IJRPC. 2013; 3(2).
- http://blog.jigschemical.com/what-are-nutraceuticals/
- https://www.curegarden.in/blogs/curegarden-team/nutraceuticals-the-new-breed
- Lipi Das, Eshani Bhaumik, Utpal Raychaudhuri and Runu Chakraborty. Role of nutraceuticals in human health. J Food Sci Technol. 2012; 49(2):173–183. DOI 10.1007/s13197-011-0269-4 https://www.crchealth.com/types-of-therapy/nutraceutical-therapy/
- Chanda Silpi, Tiwari Raj Kumar, Arun Singh Kuldeep. Nutraceuticals Inspiring the Current Therapy for Lifestyle Diseases. Advances in Pharmacological Sciences. 2019. 1-5. 10.1155/2019/69087
- Klatte ET, Scharre DW, Nagaraja HN, Davis RA, Beversdorf DQ. Combination therapy of donepezil and vitamin E in Alzheimer disease. Alzheimer Dis Assoc Disord. 2003; 17: 113-116
- Casey, C. F., Slawson, D. C. and Neal, L. R. Vitamin D supplementation in infants, children, and adolescents. Am. Fam. 2010; 81: 745-748.
- M. Pineiro and C. Stanton. Probiotic bacteria: legislative framework- requirements to evidence basis. The Journal of Nutrition. 2007; 137(3): 850S–853S.
- Michail, S., Sylvester, F., Fuchs, G. and Issenma, R. Clinical efficacy of probiotics: Review of the evidence with focus on children, clinical practice guideline. J Pediatr Gastroenterol Nutr. 2006; 43(4)
- Hord,N.G.Eukaryoticmicrobioticcrosstalk:potentialmechanismsfor health benefits of prebiotics and probiotics. Annu. Rev. Nutr. 2008; 28: 215–231
- www.cdc.gov/
- www.netdoctor.co.uk/
- Namdeo Shinde, Bhaskar Bangar, Sunil Deshmukh, Pratik Kumbhar. Nutraceuticals: A Review on current status. Research J. Pharm. and Tech. 2014; 7(1): 110-113.
- AvrelijaCencicandWalterChingwaru.TheRoleofFunctionalFoods, Nutraceuticals, and Food Supplements in Intestinal Health; Nutrients. 2010; 2: 611-625. doi:10.3390/nu2060611
- Elia Ranzato, Simona Martinotti, Cinzia Myriam Calabrese and Giorgio Calabrese. Role of Nutraceuticals in Cancer Therapy. Journal of Food Research. 2014; 3(4).
- Chao J, Leung Y, Wang M, Chang RC. Nutraceuticals and Their Preventive or Potential Therapeutic Value in Parkinson's disease. Nutrition Reviews. 2012; 70 (7): 373–386.
- Piero Portincasa, Leonilde Bonfrate, Ornella de Bari, Anthony Lembo, and Sarah Ballou. Irritable bowel syndrome and diet. Gastroenterology Report. 217; 5(1): 11–19.
- Rathod S, Mali S, Shinde N, Aloorkar N. Cosmeceuticals and Beauty Care Products: Current trends with future prospects. Research Journal of Topical and Cosmetic Sciences. 2020;11(1): 45-51.
- Al-Okbi, Sahar. Nutraceuticals of anti-inflammatory activity as complementary therapy for rheumatoid arthritis. Toxicology and industrial health. 2012; 30. 10.1177/0748233712462468.
- Tewari S, Ramkrishna KS. A Review on Nutraceutical: The combination of Nutrition and Pharmaceutical. J Nutraceuticals Food Sci. 2020; 3:4
- Howes, Melanie-Jayne. Phytochemicals as Anti-inflammatory Nutraceuticals and Phytopharmaceuticals. 2018; 10.1016/B978-0-12-805417-8.00028-7.
- Lama, Adriano Pirozzi, Claudio Avagliano, Carmen Annunziata, Chiara Mollica, Maria Calignano, Antonio Meli, Rosaria Mattace Raso, Giuseppina. Nutraceuticals: An integrative approach to starve Parkinson’s disease. Brain, Behavior, and Immunity - Health. 2020; 2. 100037. 10.1016/j.bbih.2020.100037.
- Hang, Liting Basil, Adeline Lim, Kah-Leong. Nutraceuticals in Parkinson’s Disease. NeuroMolecular Medicine. 2016; 18. 10.1007/s12017-016-8398-6.
- Gao, Xiang Liu, Jingwen Li, Li Liu, Wei Sun, Meiyan. A Brief Review of Nutraceutical Ingredients in Gastrointestinal Disorders: Evidence and Suggestions. International Journal of Molecular Sciences. 2020; 21. 1822. 10.3390/ijms21051822.
- Makkar, Rashita Behl, Tapan Bungau, Simona Zengin, Gokhan Mehta, Vineet Kumar, Arun Uddin, Md. Sahab Ashraf, Ghulam Abdel Daim, Mohamed Arora, Sandeep Oancea, Roxana. Nutraceuticals in Neurological Disorders. International Journal of Molecular Sciences. 2020; 21: 4424. 10.3390/ijms21124424.
- Huang, M.T, Ghai, G. Ho, Chi-Tang. Inflammatory Process and Molecular Targets for Antiinflammatory Nutraceuticals. Comprehensive Reviews in Food Science and Food Safety. 2006; 3: 127 - 139. 10.1111/j.1541-4337.2004.tb00063.x.
- Cencic, Avrelija Chingwaru, Walter. The Role of Functional Foods, Nutraceuticals, and Food Supplements in Intestinal Health. Nutrients. 2010; 2: 611-25. 10.3390/nu2060611.
- Parian, Alyssa Limketkai, Berkeley Shah, Neha Mullin, Gerard. (). Nutraceutical Supplements for Inflammatory Bowel Disease. Nutrition in clinical practice: official publication of the American Society for Parenteral and Enteral Nutrition. 2015; 30: 10.1177/0884533615586598.
- Zoltani, Csaba. Nutraceuticals in Cardiovascular Diseases. 2019; 10.1007/978-3-030-04624-8_28.
- Gupta, Bhanushree Kumar, Bhupesh Sharma, Anshuman Sori, Deeksha Sharma, Rahul Mehta, Saumya. Nutraceuticals for Antiaging. 2019. 10.1007/978-3-030-04624-8_25.
- Roudebush, Philip Davenport, Deborah Novotny, Bruce. The use of nutraceuticals in cancer therapy. The Veterinary clinics of North America. Small Animal Practice. 2004; 34: 249-69 viii. 10.1016/j.cvsm.2003.09.001.
- Taus, Marina Busni, Debora Petrelli, Massimiliano Nicolai, Albano. New nutritional approach to inflammatory bowel disease: The nutraceuticals. Mediterranean Journal of Nutrition and Metabolism. 2009; 145-148. 10.1007/s12349-008-0022-3.
- Uranga,JoséLopez-Miranda,VisitacionLombó,FelipeAbalo,Raquel. Food, nutrients and nutraceuticals affecting the course of inflammatory bowel disease. Pharmacological Reports. 2016; 68. 10.1016/j.pharep.2016.05.002.
- Larussa, Tiziana Imeneo, Maria Luzza, Francesco. Potential role of nutraceutical compounds in inflammatory bowel disease. World Journal of Gastroenterology. 2017; 23. 2483-2492. 10.3748/wjg.v23.i14.2483.
- Joshi, Vivek Alam, Shahjahan and Dimri, U. and Vinodhkumar, Obli. Veterinary Nutraceuticals: An Alternative Medicine. Indian Dairyman. 2016; 68. 90-93.
- Taillon, C and Andreasen, A. Veterinary nutraceutical medicine. The Canadian veterinary journal. La Revue Vétérinaire Canadienne. 2000; 41. 231-4.
- Beale, Brian. Use of nutraceuticals and chondroprotectants in osteoarthritic dogs and cats. The Veterinary clinics of North America. Small animal practice. 2004; 34. 271-89, viii. 10.1016/j.cvsm.2003.09.008.
- Dzanis, DA. Nutraceuticals in veterinary medicine. Australian Veterinary Journal. 1999; 77. 238-9. 10.1111/j.1751- 0813.1999.tb11709.x.
- A. S. Suresh, Bhavna Pawar. A Study of Factors of Lifestyle and its impact on Nutraceutical Consumption: India Perspective. Asian Journal of Management. 2018; 9(1):203-211.
- Sarika S. Lokhande. Role of Nutraceuticals in Various Diseases: A Comprehensive Review. Asian J. Pharm. Res. 2018; 8(4): 236-240.
- Seema Thakur, Neha Srivastava. Nutraceuticals: A Review. Asian J. Res. Pharm. Sci. 2016; 6(2): 85-94.
- Vipul Singh, Sangeeta Mahaur, Sanjay Kumar Kushwaha. Nutraceuticals: A New Golden Era in Health and Disease. Asian J. Research Chem. 2018; 11(3):652-658.
- G. Sreeramya, C.N. Nalini, Ramalakshmi.N, Kondaviti Sahini, Amudha Lakshmi.S. A new Era in Medicine – Neutraceuticals. Research J. Pharm. and Tech 2018; 11(8): 3572-3576.
- R. Arivuchudar, Tamilchudar R. An Overview on the Sway of Nutritional Supplements on Dry Eye Disease. Research J. Pharm. and Tech. 2020; 13(10):5004-5008.
- A Rajasekaran, G Sivagnanam, R Xavier. Nutraceuticals as therapeutic agents: A Review. Research J. Pharm. and Tech. 2008; 1(4): 171-174.
- Kavitha PG, M Umadevi. Medicinal Properties and Pests and Diseases of Noni - A Review. Res. J. Pharmacognosy and Phytochem. 2016; 8(1): 41-48.
- The Pharmaceutical Journal, PJ, July 2000;()::DOI:10.1211/PJ.2021.1.71102
- Divyadharsini V. Genetically Modified Foods – A Review. Research J. Pharm. and Tech. 2014; 7(3): 392-395.
- S. Subasree, Karthikeyan Murthykumar, Dr. Dhanraj. Effect of Aloe Vera in Oral Health – A Review. Research J. Pharm. and Tech. 2016; 9(5): 609-612.
- M. Vaishali. Antioxidants in Health and Diseases. Research J. Pharm. and Tech. 2014; 7(4): 489-493.
- Sripradha S., Karthikeyan Murthykumar, Subasree Soundarajan, Niha Naveed. Garlic, its Role in Oral Health-A Review. Research J. Pharm. and Tech. 2014; 7(6): 727-729.
- Tandra Das.T. Role of Antioxidants in Health and Diseases-A Review. Research J. Pharm. and Tech. 2015; 8(8): 1033-1037.
- Amina Mehrin Bano, Vishnupriya. V, Gayathri. R. Nutritional awareness among Adolescents. Research J. Pharm. and Tech. 2016; 9(7): 898-902.
- K.V. Swathi. Probiotics –A Human Friendly Bacteria. Research J. Pharm. and Tech. 2016; 9(8):1260-1262.
- Pal Neha, Joshi M. D. Piper nigrum: An Overview of effects on Human Health. Research J. Science and Tech. 2020; 12(4):331-337.
- Ponnambily Chandy Jobin. The Nutritional Status, Dietary Pattern and Health Outcomes among the Adolescent Girls in the Suburban areas of Chennai. Int. J. Nur. Edu. and Research. 2019; 7(2): 165-169.
- Suby Elizabeth Oommen. Health Care System of India–A Comparison with health indicators. Res. J. Humanities and Social Sciences. 2018; 9(3): 575-579.
- Archana A. Bele, Anubha Khale. An approach to a Nutraceutical. Research J. Pharm. and Tech. 2013; 6(10): 1161-1164.
- Artificial Intelligence in Food Industry: A Current Panorama
Authors
1 GES’s Satara College of Pharmacy, Degaon, Satara (M.S.) India 415004. Dist- Satara (M.S.), IN
Source
Asian Journal of Pharmacy and Technology, Vol 12, No 3 (2022), Pagination: 242-250Abstract
Artificial intelligence (AI) is that the theory and development of computer systems ready to perform tasks normally requiring human intelligence. With teeming competition and increasing demand within the food industry, has begun to embrace AI technologies during a bid to maximize profits and explore new ways to succeed in serve the consumers. AI has recently began to fix its application in various sector of the society with food industry as like pharmaceutical industry. This review highlights the impactful use of AI in diverse area of food sector including Sorting, Grading, Food Quality, Cleaning, Efficient Supply chain management, Microbial internal control and various method of food analysis. Chemical and Biological Sensor are used for food quality monitoring as well as application of AI to provide best quality food products. Planning of ordinary reliable procedures to regulate the standard of products may be a major objective. Despite these obstacles, research into optimizing production processes using AI is ongoing. It is crucial to emphasize, however, that the benefit of AI application in the food industry far outweigh the limitations.Keywords
Artificial Intelligence, Quality Analysis, Food Analysis, Food Quality, Machine Learning, Food Production, RegulationReferences
- Chindinma-Mary-Agbai, Application of Artificial Intelligence (AI) in food industry. GSC Biological and Pharmaceutical Sciences, 2020, 31(01), 171-178 13. 171 178.
- Kurilyak, S. Artificial Intelligence (AI) in food industry. Available from http://www.produvia.com.
- Sebastin, J. Atrificial intelligence: a real opportunity in food industry. Food Quality and Safety. 2018.
- Bandyopadhyay, K., Ghosh, S., & Gope, R. K. Application of Artificial Intelligence in Food Industry—A Review
- Marcos-Martinez D, Ayala JA, Izquierdo-Hornillos RC, de Villena FJM, Caceres JO (2011) Identification and discrimination of bacterial strains by laser induced breakdown spectroscopy and neural networks. Talanta 84(3):730–737
- Moncayo S, Manzoor S, Rosales JD, Anzano J, Caceres JO (2017) Qualitative and quantitative analysis of milk for the detection of adulteration by Laser Induced Breakdown Spectroscopy (LIBS). Food Chem 232:322–328
- Lasheras RJ, Bello-Gálvez C, Rodríguez-Celis EM, Anzano J (2011) Discrimination of organic solid materials by LIBS using methods of correlation and normalized coordinates. J Hazard Mater 192(2):704–713
- Caceres JO, Moncayo S, Rosales JD, de Villena FJM, Alvira FC, Bilmes GM (2013) Application of laser-induced breakdown spectroscopy (LIBS) and neural networks to olive oils analysis. Appl Spectrosc 67(9):1064–1072
- Cozzolino D (2014) an overview of the use of infrared spectroscopy and chemometrics in authenticity and traceability of cereals. Food Res Int 60:262–265. https://doi.org/10.1016/ j.foodres.2013.08.034
- Teixeira AM, Sousa C (2019) A review on the application of vibrational spectroscopy to the chemistry of nuts. Food Chem 277:713–724 https://doi.org/10.1016/j.foodchem.2018.11.030
- Tan HP, Ling SK, Chuah CH (2011) One- and two-dimensional Fourier transform infrared correlation spectroscopy of Phyllagathis rotundifolia. J Mol Struct 1006(1–3):297–302. https://doi.org/10.1016/j.molstruc.2011.09.023
- Rohman A (2019) the employment of Fourier transform infrared spectroscopy coupled with chemometrics techniques for traceability and authentication of meat and meat products. J Adv Vet Anim Res 6(1):9–17
- Moros J, Garrigues S, De Guardia M (2010) Vibrational spectroscopy provides a green tool for multi-component analysis. Trends Anal Chem 29(7):578–591. https://doi.org/10.1016/ j.trac.2009.12.012
- Gredilla A, De Vallejuelo SF, Elejoste N, De Diego A, Madariaga JM (2016) Trends in analytical chemistry non-destructive spectroscopy combined with chemometrics as a tool for green chemical analysis of environmental samples: a review. Trends Anal Chem 76:30–39. https://doi.org/10.1016/j.trac.2015.11.011
- Daszykowski M, Walczak B (2006) Use and abuse of chemometrics in chromatography. TrAC-Trends Anal Chem 25(11):1081–1096
- Indrayanto, G., & Rohman, A. (2020). The Use of FTIR Spectroscopy Combined with Multivariate Analysis. In Spectroscopic Techniques & Artificial Intelligence for Food and Beverage Analysis 9pp. 25-51). Springer, Singapore.
- Amarowicz R, Pegg RB (2019) Natural antioxidants of plant origin. In: Advances in Food and Nutrition Research. Academic, Cambridge
- Pérez-Cruz K, Moncada-Basualto M, Morales-Valenzuela J, Barriga-González G, Navarrete- Encina P, Núñez-Vergara L, Squella JA, Olea-Azar C (2018) Synthesis and antioxidant study of new polyphenolic hybrid-coumarins. Arab J Chem 11:525–537
- Harnly J (2017) Antioxidant Methods. J Food Compos Anal 64:145–146
- Al-Duais M, Müller L, Böhm V, Jetschke G (2009) Antioxidant capacity and total phenolics of Cyphostemma digitatum before and after processing: use of different assays. Eur Food Res Technol 228:813–821
- Cömert ED, Gökmen V (2018) Evolution of food antioxidants as a core topic of food science for a century. Food Res Int 105:76–93
- Kraybill HR, Dugan LR, Beadle BW, Vibrans FC, Swartz V, Rezabek H (1949) Butylated hydroxyanisole as an antioxidant for animal fats. J Am Oil Chem Soc 26:449–453
- Kraybill HR, Dugan LR (1954) Antitoxidants, new developments for food use. J Agric Food Chem 2:81–84
- Moncada-Basualto, M., & Olea-Azar, C. (2020). Spectrophotometric Methods and Electronic Spin Resonance for Evaluation of Antioxidant Capacity of Food. In Spectroscopic Techniques & Artificial Intelligence for Food and Beverage Analysis (pp. 53-75). Springer, Singapore.
- Codex Alimentarius Commission. (1984). Codex general standard for irradiated foods and recommended international code of practice for the operation of radiation facilities used for the treatment of foods. CAC/VOL, XV, FAO, Rome.
- PN-EN 1788:2002: Foodstuffs – Thermoluminescence detection of irradiated food from which silicate minerals can be isolated. European Committee for Standardisation, Brussels 2002. EN 1788 was published in 1996
- Guzik, G. P., & Stachowicz, W. (2020). Thermoluminescence the Method for the Detection of Irradiated Foodstuffs. In Spectroscopic Techniques & Artificial Intelligence for Food and Beverage Analysis (pp. 77-93). Springer, Singapore.
- Mustafa, F., & Andreescu, S. (2018). Chemical and Biological sensors for food-quality monitory and smart packaging. Food, 7(10), 168.
- Rodriguez-Aguilera R., Oliveira J.C. Review of design engineering methods and applications of active and modified atmosphere packaging systems. Food Eng. Rev. 2009; 1:66–83.
- Neethirajan S., Jayas D.S. Nanotechnology for the food and bioprocessing industries. Food Bioprocess Technol. 2011; 4:39–47.
- Wang S., Liu X., Yang M., Zhang Y., Xiang K., Tang R. Review of time temperature indicators as quality monitors in food packaging. Packag. Technol. Sci. 2015;28:839– 867:
- 3M™ MonitorMark™ Time Temperature Indicators. [Accessed on 21 August 2021]; Available online: https://www.3m.com/3M/en_US/company-us/all-3m-products/~/MONMARK-3M-MonitorMark-Time-Temperature-Indicators/?N=5002385+3293785721&rt=rud.
- Time Temperature Indicators. [(accessed on 21 August 2021)]; Available online: http://freshpoint-tti.com/time-temperature-indicators/
- Jones P., Clarke-Hill C., Hillier D., Comfort D. The benefits, challenges and impacts of radio frequency identification technology (RFID) for retailers in the UK. Mark. Intell. Plan. 2005; 23:395–402.
- Biosensors. [Accessed on 21 August 2018]; Available online: http://www2.Flex-alert.Com/flexalert/applications/biosensors.
- How Ripe Do You Like It. [(accessed on 21 August 2018)]; Available online: http://www.ripesense.co.nz/
- Ashie I., Smith J., Simpson B., Haard N.F. Spoilage and shelf-life extension of fresh fish and shellfish. Crit. Rev. Food Sci. Nutr. 1996; 36:87–121.
- Maier D., Channaiah L., Martinez-Kawas A., Lawrence J., Chaves E., Coradi P., Fromme G. Monitoring carbon dioxide concentration for early detection of spoilage in stored grain. Julius-Kühn-Archiv. 2010; 425:505.
- Malvano F., Albanese D., Pilloton R., Di Matteo M. A new label-free impedimetric aptasensor for gluten detection. Food Control. 2017; 79:200–206.
- Nassef H.M., Bermudo Redondo M.C., Ciclitira P.J., Ellis H.J., Fragoso A., O’Sullivan C.K. Electrochemical immunosensor for detection of celiac disease toxic gliadin in foodstuff. Anal. Chem. 2008; 80:9265–9271.
- Zain M. E. Impact of Mytotoxins on humans and animals. J. Saudi Chem. Soc. 2011; 15:129-144.
- Bonel L., Vidal J.C., Duato P., Castillo J.R. An electrochemical competitive biosensor for ochratoxin a based on a DNA biotinylated aptamer. Biosens. Bioelectron. 2011; 26:3254–3259.
- Buzby J.C., Wells H.F., Axtman B., Mickey J. Supermarket loss estimates for fresh fruit, vegetables, meat, poultry, and seafood and their use in the ERS loss-adjusted food availability data. Econ. Inf. Bull.-USDA Econ. Res. Serv. 2009; 44:26.
- Prescott S.L., Pawankar R., Allen K.J., Campbell D.E., Sinn J.K., Fiocchi A., Ebisawa M., Sampson H.A., Beyer K., Lee B.-W. A global survey of changing patterns of food allergy burden in children. World Allergy Organ. J. 2013; 6:1.
- Test Your Food for Peanuts: anytime, Anywhere. [(accessed on 21 August 2018)]; Available online: https://nimasensor.Com/peanut/
- Centers for Disease Control and Prevention (CDC) Foodborne Illness: Frequently Asked Questions. CDC; Atlanta, GA, USA: 2018.
- Centers for Disease Control and Prevention Surveillance for foodborne disease outbreaks-united states, 2009–2010. MMWR Morb. Mortal. Wkly. Rep. 2013; 62:41.
- Beumer R.R., Brinkman E. Detection of Listeria spp. With a monoclonal antibody-based enzyme-linked immunosorbent assay (ELISA) Food Microbiol. 1989;6:171–177
- Gossner C.M.-E., Schlundt J., Embarek P.B., Hird S., Lo-Fo-Wong D., Beltran J.J.O., Teoh K.N., Tritscher A. The melamine incident: Implications for international food and feed safety. Environ. Health Perspect. 2009; 117:1803.
- Ping H., Zhang M., Li H., Li S., Chen Q., Sun C., Zhang T. Visual detection of melamine in raw milk by label-free silver nanoparticles. Food Control. 2012; 23:191– 197.
- Boujtita M., Hart J.P., Pittson R. Development of a disposable ethanol biosensor based on a chemically modified screen-printed electrode coated with alcohol oxidase for the analysis of beer. Biosens. Bioelectron. 2000; 15:257–263.
- Mello L.D., Sotomayor M.D.P.T., Kubota L.T. HRP-based amperometric biosensor for the polyphenols determination in vegetables extract. Sens. Actuators B Chem. 2003; 96:636–645.
- Apetrei C., Rodriguez-Mendez M., De Saja J. Modified carbon paste electrodes for discrimination of vegetable oils. Sens. Actuators B Chem. 2005; 111:403–409.
- Jinap S., Hajeb P. Glutamate. Its applications in food and contribution to health. Appetite. 2010; 55:1–10.
- Choi D.W. Glutamate neurotoxicity and diseases of the nervous system. Neuron. 1988; 1:623–634.
- Karyakin A.A., Karyakina E.E., Gorton L. Amperometric biosensor for glutamate using prussian blue-based “artificial peroxidase” as a transducer for hydrogen peroxide. Anal. Chem. 2000; 72:1720–1723.
- https://www.linkedin.com/pulse/can-artificial-intelligence-save-food-industry-aidan-connolly.
- Pesapane, F., Volonté, C., Codari, M., and Sardanelli, F. (2018). Artificial intelligence as a medical device in radiology: ethical and regulatory issues in Europe and the United States. Insights into imaging, 9(5), 745-753.
- Harvey, H. B., & Gowda, V. (2020). How the FDA regulates AI. Academic radiology, 27(1), 58-61.
- Rathod S, Mali S, Shinde N, Aloorkar N. Cosmeceuticals and Beauty Care Products: Current trends with future prospects. Research Journal of Topical and Cosmetic Sciences. 2020;11(1):45-51.
- Kale N, Rathod S, More S, Shinde N. Phyto-Pharmacological Profile of Wrightia tinctoria. Asian Journal of Research in Pharmaceutical Sciences. 2021 Nov 26;11(4):301-8.
- Sanket Rathod, Ketaki Shinde, Namdeo Shinde, Nagesh Aloorkar. Cosmeceuticals and Nanotechnology in Beauty Care Products. Research Journal of Topical and Cosmetic Sciences. 2021; 12(2):93-1.
- The mRNA Vaccine Heralds a New Era in Vaccinology
Authors
1 GES’s Satara College of Pharmacy, Degaon, Satara, 415004, Maharashtra, IN
Source
Asian Journal of Pharmacy and Technology, Vol 12, No 3 (2022), Pagination: 257-265Abstract
Vaccination has had a significant impact on infectious diseases control. However, there are still a number of infectious diseases for which an effective vaccine has yet to be developed. There has been a lot of interest in RNA-based technologies for the creation of therapeutic vaccines over the last two decades. The adaptability of mRNA vaccines, as well as their potential to trigger cellular and humoral responses, are among their benefits. Furthermore, because of their intricate interaction with pattern recognition receptors (PRRs), mRNAs have inherent adjuvant qualities. This identification can be advantageous in terms of stimulating antigen-presenting cells (APCs) or harmful in terms of limiting mRNA translation indirectly. We highlight how numerous innate response mechanisms are triggered by mRNA molecules, and how each element, from the 5' cap to the poly-A tail, interferes with innate/adaptive immune responses. mRNA vaccines have the ability to be developed quickly and to be a strong tool in the fight against infectious illnesses. This article provides a thorough overview of mRNA vaccines, including recommendations for future mRNA vaccine development, as well as safety concerns and personalised vaccines. We focused on mRNA delivery and immunological activation, both which have important role for successful mRNA vaccination.Keywords
Delivery Carriers, Dendritic Cells, Infectious Diseases, Immunity, Mechanism, mRNA, mRNA VaccineReferences
- Halliday, J. "Chapter Twenty-Two - Commercial Aspects of Vaccine Development." Mariusz Skwarczynski and Istvan Toth. Micro- and Nanotechnology in Vaccine Development. William Andrew Publishing, (2017). 411-421. DOI: https://doi.org/10.1016/B978-0-323-39981-4.00022-1
- Depelsenaire, A.C.I., et al. "Chapter Three - Introduction to Vaccines and Vaccination." Mariusz Skwarczynski, Istvan Toth. Micro and Nanotechnology in Vaccine Development. William Andrew Publishing, (2017). 47-62. DOI: https://doi.org/10.1016/B978-0-323-39981-4.00003-8
- Pujar, N. S, S. L. Sagar and A. L. Lee. "1- History of Vaccine Process Development." Emily P. Wen, Ronald Ellis and Narahari S. Pujar. Vaccine Development and Manufacturing. First Edition. Hoboken, New Jersey: John Wiley & Sons, Inc., (2015). 1-24.
- Kellie, S and Z Al-Mansour. "Chapter Four - Overview of the Immune System." Mariusz, Skwarczynski and Toth Istvan. Micro and Nanotechnology in Vaccine Development. William Andrew Publishing, (2017). 63-81. DOI: https://doi.org/10.1016/B978-0-323-39981-4.00004-X
- Deborah L. Novicki. "Chapter 8 - Introduction to Vaccines and Adjuvants." Lisa M. Plitnick and Danuta J. Herzyk. Nonclinical Development of Novel Biologics, Biosimilars, Vaccines and Specialty Biologics. Academic Press, (2013). 213-224. DOI: https://doi.org/10.1016/B978-0-12-394810-6.00008-3
- Plotkin, S. L. and Plotkin, S. A. "1 - A short history of vaccination." Stanley A. Plotkin, Walter A. Orenstein and Paul A. Offit. Vaccines. Sixth Edition. Saunders, (2013). 1-13. DOI: https://doi.org/10.1016/B978-0-323-35761-6.00001-8
- D’Amico, C, et al. "Development of vaccine formulations: past, present, and future." Drug Delivery and Translational Research 11.2 (2021): 353-372. DOI: https://doi.org/10.1007/s13346-021-00924-7
- HHS.gov. Vaccine Types. HHS.gov Immunization. [Online] [Cited: 06 09, 2021.] https://www.hhs.gov/immunization/about-us/index.html.
- Azad, N and Y Rojanasakul. "Vaccine delivery-current trends and future." Current drug delivery 3.2 (2006): 137-146. DOI: https://doi.org/10.2174/156720106776359249
- Xu, S, et al. "mRNA vaccine era—mechanisms, drug platform and clinical prospection." International Journal of Molecular Sciences 21.18 (2020): 6582. DOI: https://doi.org/10.3390/ijms21186582
- Lu, Y and M Burnier. "Immunization, Vaccines, and Immunomodulation." Peter Nilsson, Michael Olsen and Stephane Laurent. Early Vascular Aging (EVA). Academic Press, (2015). 347-356.
- Cao, Y. and Gao, G. F. "mRNA vaccines: A matter of delivery." EClinicalMedicine 32 (2021).
- Kim, J., et al. "Self-assembled mRNA vaccines." Advanced drug delivery reviews 170 (2021): 83-112.
- Plotkin, S A. "Vaccines, vaccination, and vaccinology." The Journal of infectious diseases 187.9 (2003): 1349-1359.
- Warrington, Richard, et al. "An introduction to immunology and immunopathology." Allergy, Asthma & Clinical Immunology 7.1 (2011): 1-8.
- Tao, X. and Xu, A. "Basic knowledge of immunology." Amphioxus immunity. Academic Press, (2016). 15-42.
- Verbeke, Rein, et al. "Three decades of messenger RNA vaccine development." Nano Today 28 (2019): 100766.
- Pardi, N, M J Hogan and D Weissman. "Recent advances in mRNA vaccine technology." Current opinion in immunology 65 (2020): 14-20.
- Brenner, S., Jacob, F. and Meselson, M. "An unstable intermediate carrying information from genes to ribosomes for protein synthesis." 190.4776 (1961): 576-581.
- Isaacs, A., R. A. Cox, and Z. Rotem. "Foreign nucleic acids as the stimulus to make interferon." Lancet (1963): 113-16.
- Furuichi, Yasuhiro, and Kin-Ichiro Miura. "A blocked structure at the 5′ terminus of mRNA from cytoplasmic polyhedrosis virus." Nature 253.5490 (1975): 374-375.
- Dimitriadis, Giorgos J. "Translation of rabbit globin mRNA introduced by liposomes into mouse lymphocytes." Nature 274.5674 (1978): 923-924.
- Krieg, Paul A., and D. A. Melton. "Functional messenger RNAs are produced by SP6 in vitro transcription of cloned cDNAs." Nucleic Acids Research 12.18 (1984): 7057-7070.
- Martinon, Frédéric, et al. "Induction of virus‐specific cytotoxic T lymphocytes in vivo by liposome‐entrapped mRNA." European journal of immunology 23.7 (1993): 1719-1722.
- Conry, Robert M., et al. "Characterization of a messenger RNA polynucleotide vaccine vector." Cancer research 55.7 (1995): 1397-1400.
- Heiser, Axel, et al. "Autologous dendritic cells transfected with prostate-specific antigen RNA stimulate CTL responses against metastatic prostate tumors." The Journal of clinical investigation 109.3 (2002): 409-417.
- Karikó, Katalin, et al. "Suppression of RNA recognition by Toll-like receptors: the impact of nucleoside modification and the evolutionary origin of RNA." Immunity 23.2 (2005): 165-175.
- Karikó, Katalin, et al. "Incorporation of pseudouridine into mRNA yields superior nonimmunogenic vector with increased translational capacity and biological stability." Molecular therapy 16.11 (2008): 1833-1840.
- Weide, Benjamin, et al. "Direct injection of protamine-protected mRNA: results of a phase 1/2 vaccination trial in metastatic melanoma patients." Journal of immunotherapy 32.5 (2009): 498-507.
- Kreiter, Sebastian, et al. "Intranodal vaccination with naked antigen-encoding RNA elicits potent prophylactic and therapeutic antitumoral immunity." Cancer research 70.22 (2010): 9031-9040.
- Petsch, Benjamin, et al. "Protective efficacy of in vitro synthesized, specific mRNA vaccines against influenza A virus infection." Nature biotechnology 30.12 (2012): 1210-1216.
- Geall, Andrew J., et al. "Nonviral delivery of self-amplifying RNA vaccines." Proceedings of the National Academy of Sciences 109.36 (2012): 14604-14609.
- Sahin, Ugur, et al. "Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer." Nature 547.7662 (2017): 222-226.
- Zhang, Cuiling, et al. "Advances in mRNA vaccines for infectious diseases." Frontiers in Immunology 10 (2019): 594.
- Blakney, Anna K., Shell Ip, and Andrew J. Geall. "An update on self-amplifying mRNA vaccine development." Vaccines 9.2 (2021): 97.
- Verbeke, Rein, et al. "The dawn of mRNA vaccines: The COVID-19 case." Journal of Controlled Release 333 (2021): 511-520.
- Iavarone, Carlo, et al. "Mechanism of action of mRNA-based vaccines." Expert review of vaccines 16.9 (2017): 871-881.
- Pardi, Norbert, et al. "mRNA vaccines—a new era in vaccinology." Nature reviews Drug discovery 17.4 (2018): 261-279.
- Zeng, Chunxi, et al. "Formulation and delivery technologies for mRNA vaccines." (2020): 1-40.
- Midoux, Patrick, and Chantal Pichon. "Lipid-based mRNA vaccine delivery systems." Expert review of vaccines 14.2 (2015): 221-234.
- Park, Kyung Soo, et al. "Non-viral COVID-19 vaccine delivery systems." Advanced drug delivery reviews (2020).
- Jabbal-Gill, Inderjit. "Nasal vaccine innovation." Journal of drug targeting 18.10 (2010): 771-786.
- Belgharbi, Lahouari, Nora Dellepiane, and David J. Wood. "Regulation of vaccines in developing countries." Vaccines. WB Saunders, 2013. 1454-1463.
- Şenel, Sevda, M. Kürşat Derıcı, and Burcu Devrım. "Regulatory Aspects of Vaccines." FABAD Journal of Pharmaceutical Sciences 45.2 (2020): 153-160.
- Knezevic, Ivana, et al. "Development of mRNA Vaccines: Scientific and Regulatory Issues." Vaccines 9.2 (2021): 81.
- Baylor, Norman W., and Valerie B. Marshall. "Regulation and testing of vaccines." Vaccines (2013): 1427.
- Plitnick, Lisa M. "Global regulatory guidelines for vaccines." Nonclinical development of novel biologics, biosimilars, vaccines and specialty biologics. Academic Press, 2013. 225-241.
- Chen, Gang, et al. "COVID-19 mRNA Vaccines Are Generally Safe in the Short Term: A Vaccine Vigilance Real-World Study Says." Frontiers in immunology 12 (2021): 1843.
- Hou, Changshun, et al. "Up-to-date vaccine delivery systems: robust immunity elicited by multifarious nanomaterials upon administration through diverse routes." Biomaterials science 7.3 (2019): 822-835.
- Fujita, Y., and H. Taguchi. "Nanoparticle-based peptide vaccines." Micro and Nanotechnology in Vaccine Development. William Andrew Publishing, 2017. 149-170.
- Tan, Lu, and Xun Sun. "Recent advances in mRNA vaccine delivery." Nano Research 11.10 (2018): 5338-5354.
- Menon, Ipshita, et al. "Microneedles: A new generation vaccine delivery system." Micromachines 12.4 (2021): 435.
- Sahin, Ugur, Katalin Karikó, and Özlem Türeci. "mRNA-based therapeutics—developing a new class of drugs." Nature reviews Drug discovery 13.10 (2014): 759-780.
- Plotkin, Stanley A., and Susan L. Plotkin. "The development of vaccines: how the past led to the future." Nature Reviews Microbiology 9.12 (2011): 889-893.
- Claire-Anne Siegrist. "2 - Vaccine immunology." Stanley A. Plotkin, Walter A. Orenstein and Paul A. Offit. Vaccines. Sixth Edition. Saunders, (2013). 14-32.
- Sun, Jing, and Zhibo Li. "Peptoid applications in biomedicine and nanotechnology." Peptide Applications in Biomedicine, Biotechnology and Bioengineering. Woodhead Publishing, 2018. 183-213.
- Koh, Kai Jun, et al. "Formulation, characterization and evaluation of mRNA-loaded dissolvable polymeric microneedles (RNApatch)." Scientific reports 8.1 (2018): 1-11.
- Sahu, Itishri, et al. "Recent developments in mRNA-based protein supplementation therapy to target lung diseases." Molecular Therapy 27.4 (2019): 803-823.
- Noor, Rashed. "Developmental Status of the Potential Vaccines for the Mitigation of the COVID-19 Pandemic and a Focus on the Effectiveness of the Pfizer-BioNTech and Moderna mRNA Vaccines." Current clinical microbiology reports (2021): 1-8.
- Wadhwa, Abishek, et al. "Opportunities and challenges in the delivery of mRNA-based vaccines." Pharmaceutics 12.2 (2020): 102.
- Particle Engineering for Customized Drug Particles and Its Applications
Authors
1 GES’s Satara College of Pharmacy, Degaon, Satara (M.S.) 415004, IN
Source
Asian Journal of Pharmaceutical Research, Vol 12, No 4 (2022), Pagination: 349 - 358Abstract
Particle engineering is a technique that involves the customization of particles in order to get desired properties of the pharmaceutical products. The use of particle engineering is in obtaining optimum particle size and particle size distribution and getting particles of desired size. The other aspects of the particle engineering involves the morphological changes of the drug substances. The particle engineering involves improvement of physicochemical properties such as solubility, stability, improved bioavailability and formulation of novel drug delivery systems such as pulmonary drug delivery system. This article includes various techniques used for the particle engineering such as Micronization, Spray drying, high pressure homogenization, Supercritical fluid technology and freeze drying. Article also covers the different uses of particle engineering in pharmaceutical industry.
Keywords
Cocrystals, Micronization, Particle Engineering, Pulmonary Drug Delivery, Solubility, StabilityReferences
- Tanhaei, M. Mohammadi, H. Hamishehkar, et al., Electrospraying as a novel method of particle engineering for drug delivery vehicles, Journal of Controlled Release (2020), https://doi.org/10.1016/j.jconrel.2020.10.059
- Vandana KR, Raju YP, Chowdary VH, Sushma M, Kumar NV. An overview on in situ micronization technique–An emerging novel concept in advanced drug delivery. Saudi Pharmaceutical Journal. 2014 Sep 1;22(4):283-9.
- Blagden N, de Matas M, Gavan PT, York P. Crystal engineering of active pharmaceutical ingredients to improve solubility and dissolution rates. Advanced Drug Delivery Reviews. 2007 Jul 30;59(7):617-30.
- Sathisaran I, Dalvi SV. Engineering cocrystals of poorly water-soluble drugs to enhance dissolution in aqueous medium. Pharmaceutics. 2018 Sep;10(3):108.
- Kim S, Wei C, Kiang S. Crystallization process development of an active pharmaceutical ingredient and particle engineering via the use of ultrasonics and temperature cycling. Organic Process Research & Development. 2003 Nov 21;7(6):997-1001.
- Edueng K, Mahlin D, Larsson P, Bergström CA. Mechanism-based selection of stabilization strategy for amorphous formulations: Insights into crystallization pathways. Journal of Controlled Release. 2017 Jun 28;256:193-202.
- Laitinen R, Lobmann K, Strachan CJ, Grohganz H, Rades T. Emerging trends in the stabilization of amorphous drugs. International Journal of Pharmaceutics. 2013 Aug 30;453(1):65-79.
- KhadkaP,RoJ,KimH,KimI,KimJT,KimH,ChoJM,YunG,Lee J. Pharmaceutical particle technologies: An approach to improve drug solubility , dissolution and bioavailability . Asian Journal of Pharmaceutical Sciences. 2014 Dec 1;9(6):304-16.
- Midoux N, Hošek P, Pailleres L, Authelin JR. Micronization of pharmaceutical substances in a spiral jet mill. Powder Technology. 1999 Sep 1;104(2):113-20.
- Pasquali I, Bettini R, Giordano F. Solid-state chemistry and particle engineering with supercritical fluids in pharmaceutics. European Journal of Pharmaceutical Sciences. 2006 Mar 1;27(4):299-310.
- Albert H. L. Chow,1,4 Henry H. Y. Tong,2 Pratibhash Chattopadhyay,3 and Boris Y. Shekunov3, Particle Engineering for Pulmonary Drug Delivery, Pharmaceutical Research, Vol. 24, No. 3, March 2007 (# 2007) DOI: 10.1007/s11095-006-9174-3
- Shoyele SA, Cawthorne S. Particle engineering techniques for inhaled biopharmaceuticals. Advanced Drug Delivery Reviews. 2006 Oct 31;58(9-10):1009-29.
- Giry K, Péan JM, Giraud L, Marsas S, Rolland H, Wüthrich P. Drug/lactose co-micronization by jet milling to improve aerosolization properties of a powder for inhalation. International Journal of Pharmaceutics. 2006 Sep 14;321(1-2):162-6.
- Kougoulos E, Smales I, Verrier HM. Towards integrated drug substance and drug product design for an active pharmaceutical ingredient using particle engineering. AAPS Pharmscitech. 2011 Mar;12(1):287-94.
- El-Gendy N, Bailey MM, Berkland C. Particle engineering technologies for pulmonary drug delivery. InControlled pulmonary drug delivery 2011 (pp. 283-312). Springer, New York, NY.
- Herpin MJ, Smyth HD. Super-heated aqueous particle engineering (SHAPE): A novel method for the micronization of poorly water soluble drugs. Journal of Pharmaceutical Investigation. 2018 Jan;48(1):135-42.
- Moura C, Neves F, Costa E. Impact of jet-milling and wet-polishing size reduction technologies on inhalation API particle properties. Powder Technology. 2016 Sep 1;298:90-8.
- Brunaugh A, Smyth HD. Process optimization and particle engineering of micronized drug powders via milling. Drug Delivery and Translational Research. 2018 Dec 15;8(6):1740-50.
- Fukunaka T, Sawaguchi K, Golman B, Shinohara K. Effect of particle shape of active pharmaceutical ingredients prepared by fluidized-bed jet-milling on cohesiveness. Journal of Pharmaceutical Sciences. 2005 May 1;94(5):1004-12.
- Silva AS, Tavares MT, Aguiar-Ricardo A. Sustainable strategies for nano-in-micro particle engineering for pulmonary delivery. Journal of Nanoparticle Research. 2014 Nov;16(11):1-7.
- Vehring R. Pharmaceutical particle engineering via spray drying. Pharmaceutical Research. 2008 May;25(5):999-1022.
- Kaialy W, Nokhodchi A. Particle engineering for improved pulmonary drug delivery through dry powder inhalers. Pulmonary drug delivery: advances and challenges. Eds. Nokhodchi, A., Martin, GP. 2015 May 29:171-98.
- Kumar RS, Sai TM. Particle Engineering Techniques: A Boon in Enhancing Dissolution Rate of Poorly Water Soluble Drugs. Journal of Drug Delivery and Therapeutics. 2019 Dec 18;9(4-A):897-900.
- Hu J. A nanoparticle engineering process: Spray-freezing into liquid to enhance the dissolution of poorly water soluble drugs. The University of Texas at Austin; 2003.
- Rogers TL, Nelsen AC, Sarkari M, Young TJ, Johnston KP, Williams RO. Enhanced aqueous dissolution of a poorly water soluble drug by novel particle engineering technology: Spray-freezing into liquid with atmospheric freeze-drying. Pharmaceutical Research. 2003 Mar; 20(3): 485-93.
- Patel RP, Patel MP, Suthar AM. Spray drying technology: an overview. Indian Journal of Science and Technology. 2009 Oct 1;2(10):44-7.
- Arpagaus C. Pharmaceutical particle engineering via nano spray drying—process parameters and application examples on the laboratory-scale. Int. J. Med. Nano Res. 2018;5(1):026.
- Khandouzi F, Daman Z, Gilani K. Optimized particle engineering of fluticasone propionate and salmeterol xinafoate by spray drying technique for dry powder inhalation. Advanced Powder Technology. 2017 Feb 1;28(2):534-42.
- Deelip Derle*1, Jatin Patel1, Devendra Yeole1, Amit Patel1, Ashok Pingle1, Particle Engineering Techniques To Enhance Dissolution Of Poorly Water Soluble Drugs, International Journal Of Current Pharmaceutical Research Vol 2, Issue 1, 2010
- Sapra M, Ugrani S, Mayya YS, Venkataraman C. Estimation of critical supersaturation solubility ratio for predicting diameters of dry particles prepared by air-jet atomization of solutions. Journal of Colloid and Interface Science. 2017 Aug 15;500:172-81.
- Bohr A, P Boetker J, Rades T, Rantanen J, Yang M. Application of spray-drying and electrospraying/electospinning for poorly watersoluble drugs: A particle engineering approach. Current Pharmaceutical Design. 2014 Jan 1;20(3):325-48.
- Patel B, Gupta N, Ahsan F. Particle engineering to enhance or lessen particle uptake by alveolar macrophages and to influence the therapeutic outcome. European Journal of Pharmaceutics and Biopharmaceutics. 2015 Jan 1;89:163-74.
- Shoyele SA, Sivadas N, Cryan SA. The effects of excipients and particle engineering on the biophysical stability and aerosol performance of parathyroid hormone (1-34) prepared as a dry powder for inhalation. AAPS Pharmscitech. 2011 Mar;12(1):304-11.
- Lorraine M. Nolan, Jianhe Li, Lidia Tajber, Owen I. Corrigan, Anne Marie Healy∗,Particle engineering of materials for oral inhalation by dry powder inhalers. II—Sodium cromoglicate, International Journal of Pharmaceutics 405 (2011) 36–46 doi:10.1016/j.ijpharm.2010.11.040
- Bjornmalm M, Yan Y, Caruso F. Engineering and evaluating drug delivery particles in microfluidic devices. Journal of Controlled Release. 2014 Sep 28;190:139-49.
- Sahoo A, Suryanarayanan R, Siegel RA. Stabilization of Amorphous Drugs by Polymers: The Role of Overlap Concentration (C*). Molecular Pharmaceutics. 2020 Sep 25;17(11):4401-6.
- Klara Haas, Thomas Dohnal, Patricia Andreu, Egon Zehetner, Anke Kiesslich, Marcus V olkert, Peter Fryer, Henry Jaeger, Particle engineering for improved stability and handling properties of carrot concentrate powders using fluidized bed granulation and agglomeration, Powder Technology 370 (2020) 104–115 https://doi.org/10.1016/j.powtec.2020.04.065
- Chattoraj S, Sun CC. Crystal and particle engineering strategies for improving powder compression and flow properties to enable continuous tablet manufacturing by direct compression. Journal of Pharmaceutical Sciences. 2018 Apr 1;107(4):968-74.
- R Williams D. Particle engineering in pharmaceutical solids processing: surface energy considerations. Current Pharmaceutical Design. 2015 Jun 1;21(19):2677-94.
- Marwaha M, Sandhu D, Marwaha RK. Coprocessing of excipients: a review on excipient development for improved tabletting performance. International Journal of Applied Pharmaceutics. 2010 Apr;2(3):41-7.
- Perumalla SR, Sun CC. Enabling tablet product development of 5- fluorocytosine through integrated crystal and particle engineering. Journal of Pharmaceutical Sciences. 2014 Apr 1;103(4):1126-32.
- Solomon S, Ziaee A, Giraudeau L, O'Reilly E, Walker G, Albadarin AB. Particle engineering of excipients: A mechanistic investigation into the compaction properties of lignin and [co]-spray dried lignin. International Journal of Pharmaceutics. 2019 May 30;563:237-48.
- Martyn David Ticehursta And Ivan Marzianob, Integration Of Active Pharmaceutical Ingredient Solid Form Selection And Particle Engineering Into Drug Product Design. Journal Of Pharmacy And Pharmacology, Doi: 10.1111/Jphp.12375 (2014)
- He X, Griesser UJ, Stowell JG, Borchardt TB, Byrn SR. Conformational color polymorphism and control of crystallization of 5‐methyl‐2‐[(4‐methyl‐2‐nitrophenyl) amino]‐3‐thiophenecarbonitrile. Journal of Pharmaceutical Sciences. 2001 Mar;90(3):371-88.
- Nogueira BA, Castiglioni C, Fausto R. Color polymorphism in organic crystals. Communications Chemistry. 2020 Mar 17;3(1):1-2.
- Sharma Deepak, Kumar Dinesh, Singh Mankaran, Singh Gurmeet, Rathore Mahendra Singh, Taste Masking Technologies: A Novel Approach For The Improvement Of Organoleptic Property Of Pharmaceutical Active Substance, In International Research Journal Of Pharmacy. April 2012
- Dhakate CS, Upadhye KP, Dixit GR, Bakhale SS, Umate RM. Taste masking by co-crystallization: A review. World J Pharm Res. 2017 May 18.
- Savjani JK. Co‐crystallization: An approach to improve the performance characteristics of active pharmaceutical ingredients. Asian Journal of Pharmaceutics (AJP): Free full text articles from Asian J Pharm. 2015 Jul 15;9(3):147-51.
- Wadhwa J, Puri S. Taste masking: A novel approach for bitter and obnoxious drugs. International Journal of Biopharmaceutical & Toxicological Research. 2011;1(1):47-60.
- Madene A, Jacquot M, Scher J, Desobry S. Flavour encapsulation and controlled release–a review. International Journal of Food Science & Technology. 2006 Jan;41(1):1-21.
- Suphla Gupta, Saima Khan, Malik Muzafar, Manoj Kushwaha, Arvind Kumar Y adav, Ajai Prakash Gupta, Encapsulation: Entrapping Essential Oil/Flavors/ Aromas In Food, Encapsulations. Http://Dx.Doi.Org/10.1016/B978-0-12-804307-3.00006-5
- Abdou EM. Sweet co-crystals for pediatric drugs formulation. Acta Scientific Pharmaceutical Sciences. 2018;2:01.
- Antonio Tabernero, Eva M. Martín del Valle∗, Miguel A. Galán, Supercritical fluids for pharmaceutical particle engineering: Methods, basic fundamentals and modelling, Chemical Engineering and Processing 60 (2012) 9– 25 http://dx.doi.org/10.1016/j.cep.2012.06.004
- Dennehy RD. Particle engineering using power ultrasound1. Organic Process Research & Development. 2003 Nov 21;7(6):1002-6.
- Kougoulos E, Marziano I, Miller PR. Lactose particle engineering: Influence of ultrasound and anti-solvent on crystal habit and particle size. Journal of Crystal Growth. 2010 Nov 15;312(23):3509-20.
- Rojas PE, Sala S, Elizondo E, Veciana J, Ventosa N. Particle engineering with CO 2-Expanded Solvents: The DELOS platform. InAdvances in Organic Crystal Chemistry 2015 (pp. 73-93). Springer, Tokyo.
- Sowa M, Klapwijk AR, Ostendorf M, Beckmann W. Particle engineering of an active pharmaceutical ingredient for improved micromeritic properties. Chemical Engineering & Technology. 2017 Jul;40(7):1282-92.
- Vinjamuri BP, Haware RV, Stagner WC. Inhalable ipratropium bromide particle engineering with multicriteria optimization. Aaps Pharmscitech. 2017 Aug;18(6):1925-35.
- Stefan Bötschi, Ashwin Kumar Rajagopalan, Igor Rombaut Manfred Morari, Marco Mazzotti. From needle-like toward equant particles: A controlled crystal shape engineering pathway, Computers and Chemical Engineering 131 (2019) 106581 https://doi.org/10.1016/j.compchemeng.2019.106581
- Yang Y, Nie D, Liu Y, Yu M, Gan Y. Advances in particle shape engineering for improved drug delivery. Drug Discovery Today. 2019 Feb 1;24(2):575-83.
- Pallai-Varsányi E, Tóth J, Gyenis J. Drying of suspensions and solutions on inert particle surface in mechanically spouted bed dryer. China Particuology. 2007 Oct 1;5(5):337-44.
- Majerik V, Horváth G, Charbit G, Badens E, Szokonya L, Bosc N, Teillaud E. Novel particle engineering techniques in drug delivery: Review of coformulations using supercritical fluids and liquefied gases. Hungarian Journal of Industry and Chemistry. 2004 Sep 1;32(1).
- Pawar N, Saha A, Nandan N, Parambil JV. Solution cocrystallization: A scalable approach for cocrystal production. Crystals. 2021 Mar;11(3):303.
- Ronald G. Iacocca, Christopher L. Burcham, Lori R. Hilden, Particle Engineering: A Strategy For Establishing Drug Substance Physical Property Specifications During Small Molecule Development, Journal Of Pharmaceutical Sciences, Vol. 99, No. 1, January 2010
- Joshi R, Raje S, Akram W, Garud N. Particle engineering of fenofibrate for advanced drug delivery system. Future Journal of Pharmaceutical Sciences. 2019 Dec;5(1):1-1.
- Li Z, Lin X, Shen L, Hong Y, Feng Y. Composite particles based on particle engineering for direct compaction. International Journal of Pharmaceutics. 2017 Mar 15;519(1-2):272-86.
- Lobo JM, Schiavone H, Palakodaty S, York P, Clark A, Tzannis ST. SCF-engineered powders for delivery of budesonide from passive DPI devices. Journal of Pharmaceutical Sciences. 2005 Oct 1;94(10):2276-88.
- Majerik V, Horváth G, Charbit G, Badens E, Szokonya L, Bosc N, Teillaud E. Novel particle engineering techniques in drug delivery: Review of coformulations using supercritical fluids and liquefied gases. Hungarian Journal of Industry and Chemistry. 2004 Sep 1;32(1).
- Wan F, Maltesen MJ, Bjerregaard S, Foged C, Rantanen J, Yang M. Particle engineering technologies for improving the delivery of peptide and protein drugs. Journal of Drug Delivery Science and Technology. 2013 Jan 1;23(4):355-63.
- Ogain ON, Li J, Tajber L, Corrigan OI, Healy AM. Particle engineering of materials for oral inhalation by dry powder inhalers. I— Particles of sugar excipients (trehalose and raffinose) for protein delivery. International Journal of Pharmaceutics. 2011 Feb 28;405(1- 2):23-35.
- Rathod S, Mali S, Shinde N, Aloorkar N. Cosmeceuticals and Beauty Care Products: Current trends with future prospects. Research Journal of Topical and Cosmetic Sciences. 2020;11(1):45-51.
- Kale N, Rathod S, More S, Shinde N. Phyto-Pharmacological Profile of Wrightia tinctoria. Asian Journal of Research in Pharmaceutical Sciences. 2021 Nov 26;11(4):301-8.
- Sanket Rathod, Ketaki Shinde, Namdeo Shinde, Nagesh Aloorkar. Cosmeceuticals and Nanotechnology in Beauty Care Products. Research Journal of Topical and Cosmetic Sciences. 2021; 12(2):93-1.
- B.A. Bhairav, J.K. Bachhav, R.B. Saudagar. Review on Solubility Enhancement Techniques. Asian J. Pharm. Res. 2016; 6(3): 147-152.
- Rutuja S. Shah, Rutuja R. Shah, Manoj M. Nitalikar, Chandrakant S. Magdum. Microspheres by Spray Drying: An Approach to Enhance Solubility of Bicalutamide. Asian J. Pharm. Res. 2017; 7(3): 183-188.