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Authors
Affiliations
1 Centre for Chemical and Pharmaceutical Sciences, School of Basic and Applied Sciences, Central University of Punjab, Bathinda-151001, IN
2 Department of Botanical and Environmental Sciences, Guru Nanak Dev University, Amritsar, Punjab-143001, IN
Source
Journal of Natural Remedies, Vol 14, No 2 (2014), Pagination: 144-152
Abstract
Invitro anti-mutagenic potential of different extracts/fractions of Potentilla fulgens has been made by an Ames histidine reversion assay using TA98 and TA100 tester strains of Salmonella typhimurium against the direct-acting mutagens, 4-Nitro-O-phenylenediamine (NPD) and Sodium azide. P. fulgens has been used in traditional system of medicine as anti-hyperglycemic, hypoglycemic, anti-hyperlipidemic, anti-oxidant, anti-inflammatory and anti-ulcerogenic agent. Results indicated that n-butanol and water fractions showed strong inhibition activity against the mutagens (NPD, Sodium azide) in both co-incubation as well as pre-incubation treatments in TA98 and TA100 tester strains.
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