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Dhandapani, R.
- Production of Prodigiosin from Serratia marcescens Isolated from Soil
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Authors
Affiliations
1 Dept. of Microbiology, Adhiparasakthi College of Arts & Science, Kalavai-632 506, TN, IN
2 Microgeneics, Gandhi Nagar, Vellore-632 006, IN
3 Dept. of Microbiology, Periyar Univ., Salem-636 011, TN, IN
1 Dept. of Microbiology, Adhiparasakthi College of Arts & Science, Kalavai-632 506, TN, IN
2 Microgeneics, Gandhi Nagar, Vellore-632 006, IN
3 Dept. of Microbiology, Periyar Univ., Salem-636 011, TN, IN
Source
Indian Journal of Science and Technology, Vol 2, No 10 (2009), Pagination: 32-34Abstract
Prodigiosin is a promising drug owing to its reported characteristics of having antifungal, immunosuppressive and anti-proliferative activity. Prodigiosin was first characterized from Serratia marcescens. Investigations were made in the present study to screen new strains of Serratia that effectively produce prodigiosin. A new strain designated as S. marcescens NY1 was isolated. The parameters viz., temperature, pH, sugar substrate and oil substrate were optimized to increase the production of prodigiosin. It was observed that maximum amount of prodigiosin was produced at temperature 30°C and pH 7.0. Among the different sugar substrates tested maltose when amended in the medium yielded 425±40 mg/L of prodigiosin. Oil substrates play a vital role in prodigiosin production. Among the various oil substrates used the production of prodigiosin was maximum (535±45 mg/L) when the medium was amended with peanut oil.Keywords
Prodigiosin, Serratia marcescens, BiopigmentsReferences
- Anna R. Oller (2005) Media effects of sugars on pigmentation and antibiotic susceptibility in Serratiamarcescens. Sci. & Technol., Transac. of Missouri Acad. Sci. 243-246.
- Giri V. Anuradha, Nandhini Anandkumar, Geetha muthukumaran and Gautham pennathur (2004) A novel medium for the enhanced cell growth and production of prodigiosin from Serratia marcescens isolated from soil. BMC Microbiol. 4, 1-10.
- Beatriz M, Navarro S, Pique M, Vilaseca M, Martinell M, Giralt E, Gil J and Peroz-Tomas R (2000) Prodigiosin from the supernatant of Serratia marcescens induce apoptosis in haematopoietic cancer cell lines. Brit. J.Pharmacol. 131, 585-593.
- Chang S, Sanada M, Johdo O, Ohta S, Nagamatsu Y and Yoshimoto A (2000) High production of prodigiosin by Serratia marcescens grown on ethanol. Biotechnol. Lett. 22, 1761–1765.
- Demain AL (1995) In fifty years of antimicrobials: past perspectives and future trends (Eds. Hunter PA,Darby GK & Russel NJ), Soc. for Gen. Microbiol., Cambridge, 205-228.
- Frustner A (2003) Chemistry and Biology of roseopniun and the prodigiosin alkaloids: a survey ofthe last 2500 years. Angew. Chem. Int. Ed. Engl. 42, 3582-3603.
- Jungdon B, Hyunsoo M, Kyeong-Keun O, Chang-Ho K, Dae SL, Seung WK and Suk-In H (2001) A novel bioreactor with an internal adsorbent for integrated fermentation and recovery of prodigiosin like pigment produced from Serratia sp. Biotechnol. Letts. 23, 1315–1319.
- Pryce LH and Terry FW (2000) Spectrophotometric assay of gene expression: Serratia marcescens pigmentation. Bioscene. 26, 3–13.
- Shirata A, Tsukamoto P, Yasui H, Hata T, Hayasaka S, Kojima A and Kato H (2000) Isolation of bacteria producing bluish purple pigment and use for dyeing. JARQ. 34, 131-140.
- Slater H, Crow M, Everson L and Salmond GP (2003) Phosphate availability regulates biosynthesis of twoantibiotics, prodigiosin and carbapenem in Serratia via both quorum sensing- dependent and independent pathway. Mol. Microbiol. 47, 303-320.
- Srijith VM (2006) Analysis of Serratia marcescens genome – identifying the biosynthetic pathway of the pigment prodigiosin –a computational approach. Centre for Bio Informatic, Kerala Univ.
- Williams P, Bainton NJ, Swift S, Chhabra SR, Winson MK, Stewart GSAB, Salmond GPC and Bycroft BW (1992) Small molecule mediated density dependent control of gene expression in prokaryotes: bioluminescence and the biosynthesis of carbapenem antibiotics. FEMS Microbiol. Lett. 100, 161-168.
- Williams RP and Hussain Quadri SM (1980) The pigment of Serratia. CRC press, Bocaraton, USA. pp: 31-75.
- A Complete Study on Biodegradation of Reactive Red C2G29 Using Newly Isolated Acinetobacter sp
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Authors
D. Suresh
1,
P. Sridhar
1,
D. Joyce Hellen Sathya
2,
M. Anil Kumar
2,
M. Seenuvasan
2,
R. Dhandapani
3
Affiliations
1 Department of Biotechnology, Sengunthar Arts and Science College, Tiruchengode, IN
2 Department of Biotechnology, Madha Engineering College, Kunrathur, Chennai, IN
3 Department of Microbiology, Periyar University, Salem, IN
1 Department of Biotechnology, Sengunthar Arts and Science College, Tiruchengode, IN
2 Department of Biotechnology, Madha Engineering College, Kunrathur, Chennai, IN
3 Department of Microbiology, Periyar University, Salem, IN