- N. M. Bhopale
- H. S. Sawarkar
- M. B. Narkhede
- N. V. Thorat
- M. R. Bhise
- N. S. Jagtap
- V. P. Nalamwar
- A. S. Pratapwar
- P. B. Aswar
- B. S. Kuchekar
- R. Dhage
- S. P. Deshmukh
- Trapti Rastogi
- Deepali S. Ghorpade
- U. A. Deokate
- M. D. Wandhare
- S. P. Hadke
- H. A. Sawarkar
- Vijay Bhutda
- Komal Moon
- V. B. Kshirsagar
- V. B. Bharkad
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All
Khadabadi, S. S.
- Design, Development and In-vitro Evaluation of Herbal Matrix Tablet
Authors
1 IBSS College of Pharmacy, Nimbari Phata, Buldana Road, Malkapur, Dist- Buldana-443 101, IN
2 I.B.S.S. College of Pharmacy, Malkapur- 443 101 (M.S.), IN
3 Govt. College of Pharmacy, Amravati-444 603 (M.S.), IN
Source
Research Journal of Pharmaceutical Dosage Form and Technology, Vol 1, No 3 (2009), Pagination: 254-256Abstract
The purpose of the present investigation was to develop the sustain release matrix tablet of Tinospora cordifolia using the various polymers like HPMC (Hydroxy-Propyl-methyl-cellulose), Ethyl cellulose (EC), of different viscosity grade. Ethanolic extract of Tinospora cordifolia was used for the formulation of sustain release matrix tablet and tablet formulations were developed by using wet granulation method. Different diluents like lactose, magnesium stearate and cab-o-sil were used for improving flowability and compressibility. Binder such as polyvinyl pyrrolidone was used for optimization of the formulations. Sodium starch glycolate was used as disintegrating agent. Pre and post formulation parameters were studied for all the batches. HPMC –KM4 shows better result for matrix tablet in terms of sustain drug release with comparison to different viscosity grade of HPMC and ethyl cellulose. The dissolution study of the Tinospora cordifolia tablets exhibited 99.54% release of total polyphenol.Keywords
Ethanolic Extract of Tinospora Cordifolia, HPMC, Ethyl Cellulose, Matrix Tablet.- Phytochemical and Pharmacological Profile of Annona squamosa Linn:A Review
Authors
1 Govt. College of Pharmacy, Pharmacognosy and Phytochemistry Department, Kathora Naka, Amravati- 444 604 (M.S.), IN
2 Government College of Pharmacy, Amravati- 444 604 (M.S.), IN
3 S. N. Institute of Pharmacy, Pusad. Dist. Yavatmal (MS), IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 1, No 3 (2009), Pagination: 139-142Abstract
Acetogenin a different class of secondary metabolites was found in various parts of Annona squamosa L. More than 20 different acetogenins were isolated from leaves, bark, fruits and seeds. Cytotoxic and Insecticidal properties of Annona squamosa L. were attributed to acetogenins. More than 13 different alkaloids, several terpenes, kauranes were isolated. Antibacterial activity was attributed to terpenes and kauranes. Seeds of Annona squamosa yielded fixed oil containing hydroxyacids. Seeds were found to contain anti-inflammatory cyclic peptides.
Many pharmacological activities were experimentally reported on extracts of Annona squamosa L., these included Antitumour, Cytotoxic, Antiinflammatory, Analgesic, Antidiabetic, Antioxidant, Larvicidal, Insecticidal, Molluscicidal, Licicidal, Antibacterial, Nutritive, Antihtyroid.
Keywords
Annona squamosa, Phytochemical, Pharmacological Studies.- In Vitro Licicidal Activity of Different Roots and Leaves Extract of Enicostema axillare (Gentianaceae)
Authors
1 Government College of Pharmacy, Kathora Naka, Amravati- 444 604 (M.S.), IN
2 Government College of Pharmacy, Amravati 444604(M.S.), IN
3 MIT College of Pharmacy, Kothrud, Pune, IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 1, No 3 (2009), Pagination: 238-239Abstract
Enicostema axillare is well known for its anthelmintic and bacterial activity. In present study dried leaves and ischolar_mains of Enicostema axillare were subjected to exhaustic sequential extraction with four solvent i.e.-hexane, chloroform, methanol and distilled water respectively. All four extracts were studied for in vitro licicidal activity using goat-lice Damalinia caprae (Trichodectidae) as experimental organism. Only n-hexane and chloroform fractions showed statistically significant licicidal activity (p value <0.001, n = 5). Decrease in mean time required to kill the lice was observed at concentration 1% w/w and 10% w/w when compared to 1% lindane solution.
Keywords
Enicostema axillare Leaves and Roots, Licicidal Activity.- Studies on Antimicrobial Activity of Boswellia serrata, Moringa oleifera and Vitex negundo:A Comparison
Authors
1 Government College of Pharmacy, Kathora Naka Road, Amravati-444604, IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 1, No 1 (2009), Pagination: 75-77Abstract
Ethanolic extracts of gum resin of Boswellia serrata, bark of Moringa oleifera and leaves of Vitex negundo were subjected to preliminary screening for antimicrobial activity .All ethanolic extracts exhibited significant anti-microbial activity comparable to the standard drug tetracycline. The mixture of all three extracts together in equal concentration shows more inhibitory zone as compared to other extracts.
Keywords
Boswellia serrata ,Moringa oleifera,Vitex negundo, Antimicrobial.- Comparative Estimation of Curcumin Content from Marketed Herbal Anti Rheumatic Tablets Formulation
Authors
1 Dept. of Pharmacognosy and Phytochemistry, Government College of Pharmacy, Kathora Naka, Amravati-440064 (M.S.), IN
Source
Asian Journal of Research in Chemistry, Vol 2, No 3 (2009), Pagination: 340-343Abstract
A rapid and sensitive high-performance thin-layer chromatographic (HPLC) method was developed and validated for the quantitative estimation of Curcumin in formulation containing Curcuma longa extracts. Simple extraction method was used for isolation of curcumin from formulation sample. The isolated samples were chromatographed by using RP-HPLC Method on HiQ Sil C18 W 4.6 mm×250 mm i.d. column and detected by UV at 420 nm. The linearity range for Curcumin was 0.4-2.4 mcg/ml with average recovery of 97.57±0.5137. The limit of detection and limit of quantification was found to be 3.0196 and 9.1503 for curcumin respectively.The developed method was successfully applied for the assay of market formulations containing Curcuma longa extracts.Keywords
RP-HPLC, Curcuma Longa Extracts, Curcumin.- Comparative Studies on Anthelmintic Activity of Moringa Oleifera and Vitex Negundo
Authors
1 Government College of Pharmacy, Kathora Naka Road, Amravati-444604, IN
Source
Asian Journal of Research in Chemistry, Vol 2, No 2 (2009), Pagination: 181-182Abstract
Ethanolic extracts of Moringa oleifera and Vitex negundo were taken for anthelmintic activity against Indian earthworm Pheritima posthuma. Various concentrations of both extracts were tested and results were expressed in terms of time for paralysis and time for death of worms. Piperazine citrate (10 mg/ml) was used as a reference standard and distilled water as a control group. Dose dependent activity was observed in both plant extracts but Moringa oleifera shows more activity as compared to Vitex negundo.Keywords
Moringa oleifera, Vitex negundo, Anthelmintic activity, Piperazine Citrate.- HPTLC Method Development and Validation for the Simultaneous Estimation of Diosgenin and Levodopa in Marketed Formulation
Authors
1 Government College of Pharmacy, Amravati-444604 (M.S.), IN