Informatics Publishing Limited

K. Saranya ¹, V. Manivasagan ¹, N. G. Ramesh Babu ¹, D. Pradeep ¹, S. Pandidurai ¹

Affiliations
1 Department of Biotechnology, Adhiyamaan College of Engineering, Hosur, IN

Abstract

Blood substitutes are currently undergoing preliminary clinical trials to determine their safety. Two distinctly different classes of oxygen carriers are being developed, each capable of transporting and delivering oxygen to peripheral tissues. The delivery of oxygen by these two methodologies may have both benefits and risks which are unique to its class. Early clinical trials have been promising. However, effective use of these blood substitutes may involve using them in conjunction with other techniques such as normovolemic hemodilution to effectively reduce or eliminate the need for transfusions in certain instances. However, this first generation of clinically safe blood substitutes will not replace allogeneic blood transfusions as a means of treating many types of anemia.

Keywords

Hemoglobin-Based Oxygen Carriers (HBOCs), Perfluorocarbon-Based Oxygen Carriers (PFBOCs),Blood Substitute, Blood Pharming.

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V. Manivasagan ¹, K. Saranya ¹, N. G. Ramesh Babu ¹, D. Pradeep ¹, S. Pandidurai ¹

Affiliations
1 Department of Biotechnology, Adhiyamaan College of Engineering (Autonomous), Hosur – 635 109, Tamil Nadu, IN

Abstract

Biophotonics is the science of generating and harnessing light (photons) to image, detect and manipulate biological materials. Biophotonics is an emerging area of scientific research that uses light and other forms of radiant energy to understand the inner workings of cells and tissues in living organisms. The approach allows researchers to see, measure, analyze and manipulate living tissues in ways that has not been possible before. Biophotonics is used in biology to study and probe for molecular mechanisms, function of proteins, DNA and other important molecules. It is used in medicine to study tissue and blood at the macro (large-scale) and micro (very small scale) organism level to detect, diagnose and treat diseases in a way that are non-invasive to the body. Examples of biophotonics in biology and medicine include, new laser microscopes that allow measurements of single molecules and tissues at unprecedented resolution, new light-activated chemicals that can be used to weld tissues for surgical applications and to label important proteins, widely tunable ultrafast laser sources, which provide access to molecular dynamics and structure, optical coherence tomography, which allows visualization of tissues and organs.

Keywords

Biophotonics, Photons, Biology, Medicine, Tomography.

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