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Khan, Wasimuzzama
- Pharmacognostic and Preliminary Phytochemical Investigation of Argyreia nervosa Roots (Convolvulaceae)
Authors
1 Dept. of Pharmacognosy, M.C.E. Society’s Allana College of Pharmacy, Pune-411001 (M.S), IN
2 Department of Pharmacognosy, M.C.E. Society’s Allana College of Pharmacy, Pune-411001, IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 2, No 5 (2010), Pagination: 359-363Abstract
Argyreia nervosa Linn. (Argyreia speciosa) belonging to family Convolvulaceae, commonly known as elephant creeper, has been reported to have antimicrobial, hepatoprotective, nootropic, anticonvulsant, hypoglycemic, anti-oxidant, antiviral, nematicidal, aphordiasic, immunomodulatory, analgesic and anti-inflammatory activity.
Pharmacognostical parameters for the ischolar_mains were studied with the aim of contributing towards establishing monograph for this species. In pharmacognostical investigations, examination of macroscopical, microscopical characters, ash values, extractive values, foreign matter and LOD were carried out. Phytochemical screening included qualitative chemical examination and thin layer chromatography of the detected phytoconstituents.
Microscopical study showed well defined tissues like thick walled cork, cortex and phloem with resin canals, drum shaped xylem vessels etc. Preliminary phytochemical investigation of aqueous and methanolic extract of ischolar_mains of Argyreia nervosa revealed the presence of alkaloids, glycosides, amino acid, tannins and flavonoids which were further confirmed by thin layer chromatography. However flavonoids were found to be absent in chloroform extract and ethereal extract showed presence of only tannins. Thus the present work justifies our aim of detailed pharmacognostic and phytochemical investigation and chromatographic studies of the plant.
Keywords
Argyreia nervosa, Phytochemical, Convolvulaceae Flavonoids.
- Pharmacognostic and Preliminary Phytochemical Investigation of Salvadora persica Linn (Salvadoraceae)
Authors
1 Dept. of Pharmacognosy, M.C.E. Society’s Allana College of Pharmacy, Pune-411001 (M.S), IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 2, No 4 (2010), Pagination: 319-323Abstract
Salvadora persica linn. (Salvadoraceae), a desert plant, also known as toothbrush tree or Miswak is used as tooth cleaning stick in many third world countries. The aqueous and alcoholic extracts of ischolar_mains, leaves, bark and pulp of Salvadora persica linn have been found to have antimicrobial, anti-plaque, analgesic, antipyretic, antioxidant and antiulcer activity. Since the plant is not much explored pharmacognistically and phytochemically, the present work is planned to study the pharmacognostic, phytochemical and chromatographic behavior and to establish the monograph of the plant.
Microscopy of stem showed well defined single layered quadrangular celled epidermis, 7 to 8 layers of cellular cortex embedded into which are bunches of lignified pericyclic fibers and cocentric vascular bundle, Medullary rays and pith. Powder showed presence of epidermis, bordered and pitted xylem vessels, reticulate xylem parenchyma and lignified pericyclic fibers etc
The proximate analysis showed satisfactory results with respect to foreign matter, moisture content and ash values. The water soluble extractive value was found to be the highest (25.4%), whereas alcohol soluble extractive, chloroform soluble extractive and ether soluble extractive values were found as 7.6%, 6% and 3.6% respectively.
The phytochemical investigation of the stem of Salvadora persica, showed presence of Alkaloids, Glycosides, Flavonoids, Carobohydrates, Tannins and Saponins, in the aqueous extract. The ethanolic extract of the stem showed presence of Glycosides, Steroids and Flavonoids whereas Acetone extract showed presence of Steroids and Flavnoids which were confirmed by the Thin Layer Chromatography. Chloroform and ethereal extract failed to show the presence of any phytoconstituents.