- Research Journal of Science and Technology
- Research Journal of Engineering and Technology
- Asian Journal of Pharmaceutical Analysis
- International Journal of Technology
- Asian Journal of Research in Chemistry
- Research Journal of Pharmacy and Technology
- Asian Journal of Pharmacy and Technology
- Toxicology International (Formerly Indian Journal of Toxicology)
- The Indian Practitioner
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All
Gupta, Y. K.
- Statistical Assesment of Ground Water Quality using Physico-Chemical Parameters in Jhunjhunu District of Rajasthan, India
Authors
1 Department of Chemistry, Shri Jagdish Prasad Jhabarmal Tibrewala University, Vidyanagari, Jhunjhunu, Rajasthan - 333001, IN
2 Department of Chemistry, B K Birla Institute of Engineering and Technology, Pilani, Rajasthan-333031, IN
Source
Research Journal of Science and Technology, Vol 7, No 4 (2015), Pagination: 217-222Abstract
Groundwater is one of the most useful water sources for sustaining life and environment. But over the last few Decades the water quality has been deteriorated due to its over exploitation. Contamination of such water source is a big problem creating health hazards. Groundwater is the major source of drinking water in rural as well as in urban areas and over 94% of the drinking water demand is full fill by groundwater. The study has been carried out to assess the ground water quality and its appropriateness for drinking in most rural habitations of Jhunjhunu district, Rajasthan, India. In the present study groundwater samples were collected from different villages of Jhunjhunu District, Rajasthan and assessed on the basis of various parameters. The water quality parameters such as; pH, TDS, electrical conductivity, total alkalinity, total hardness, calcium hardness, magnesium hardness, carbonate, bicarbonate, sodium, potassium, fluoride, sulphate and nitrate have been analyzed. The study revealed that the water confirms to drinking water quality standards at some places whereas at some places it was totally unfit for human consumption.Keywords
Groundwater Quality, Statistical Parameters, Physico-Chemical Parameters, pH, TDS, Total Hardness, Electrical Conductivity, Calcium, Hardness, Magnesium Hardness, Carbonate, Bicarbonate, Sodium, Potassium, Fluoride, Sulphate and Nitrate.- Synthesis and Antimicrobial Activities of Zn (II) Complex of 2,5-Diamino-1,3,4-Thiadiazole
Authors
1 Department of Chemistry, Agra College, Agra, U.P., IN
2 Department of Chemistry, B K Birla Institute of Engineering and Technology, Pilani, Rajasthan, IN
Source
Research Journal of Science and Technology, Vol 5, No 4 (2013), Pagination: 462-465Abstract
Aim:
The ligands contain O, N, S-Sequence and their metal complexes have their various chemical and structural characteristics and their wide application in the field of pharmacology. The extreme efforts have been made to design novel drug to strains of resistant micro-organisms. This has required the need to search for more efficient drugs.
The Zn (II) metal complexes with a tridentate ligand 2,5-diamino-1,3,4-thiadiazole has been prepared by cyclisation of bithiourea in a 3% hydrogen peroxide medium. 2,5-diamino-1,3, 4-thiadiazole acts as neutral tridentate ligand and coordinates through the sulphur atom and nitrogen of the amines. The complexes are non-electrolyte in DMF. The complexes exhibited octahedral geometry. The antimicrobial activities of ligand and its complexes were screened using sensitivity test, minimum inhibition concentration and minimum bacterial concentration method. Metal chelates showed greater antimicrobial activities as compared to the control and the ligand. The metal chelates and the ligand did not exhibited activity against Aspergillus niger and Penicillin species.
Methods:
Elemental analyses, IR spectra, magnetic susceptibilities by using Faraday Balance, molar conductance by using Genway 4200 conductivity meter. Metal estimation by using Alpha 4 Atomic Absorption Spectrophotometer. Thin layer chromatography was carried out using TLC plate coated with silica gel.
Results:
The results of the elemental analyses are in good agreement with those calculated for the suggested formulae, 1:2 (M: L) solid chelates are isolated and found to have the general formulae [(ML2)] X2; M=Zn (II) (X=Cl).
The IR spectra revealed that the ligand L is a neutral tridentate ligand. It coordinated to the metal ions via the nitrogen of the amines and sulphur atom. The molar conductance value of the Zn (II) complex was low which indicate the nonelectrolytic nature of the complex. The ligand and metal complexes show antimicrobial effect against the tested organism species except against molds of penicillin and Aspergillius. Niesseria gonorrhoea was probably the most sensitive organism to the 2,5-Diamino-1,3,4-Thiadizole and its metal complexes. Metal complexes showed greater activity against some of the micro-organisms compared to the parent compounds
Conclusion:
In this paper we conclude from combined results of the chemical and physical analysis that the ligand (2,5-diamino-1,3,4-thiadiazole) coordinated with Zn. The metal complexes possess better physical properties than the parent compound. Metal complex of 2,5-diamino-1,3,4-thiadiazole would be a better therapeutic drug for antibacterial treatment.
Keywords
Zn (II) Complex, Cyclisation, 2,5-Diamino-1,3,4-Thiadiazole, Antimicrobial Activities.- Synthesis and Antimicrobial Activity of Zn(II) and Fe(II) Complexes Derived from Enamine
Authors
1 Department of Chemistry, Agra College, Agra, U.P, IN
2 Department of Chemistry, B K Birla Institute of Engineering and Technology, Pilani, Rajasthan, IN
Source
Research Journal of Engineering and Technology, Vol 5, No 4 (2014), Pagination: 178-183Abstract
The Zn(II) and Fe(II) Complexes were prepared by the action of equimolar ethanolic solutions with the ligands (HL1, HL2 and HL3) with ethanolic metal solutions. Where HL1= 4-N,N-diethylamine-pent-3-ene-2-one, HL2=4-N,N-di npropylamine- pent-3-ene-2-one and HL3=4-N,N-dicyclohexylamine-pent-3-ene-2-one.
The complexes prepared, were characterized by IR, UV and atomic absorption spectroscopy. The metal complexes and Ligands were screened against Escherichia coli and Staphylococcus aureus bacteria to assess their antimicrobial activity by disc diffusion method. The Ligands were absolutely inactive against bacteria where as the complex of Zn (HL1) has significant action on both bacteria, which show a good potential as bactericide and other complexes have normal antiseptic character.
Keywords
Zn(II) and Fe(II) Complexes of Enamine, Antimicrobial Activity.- Synthesis, Characterization and Antimicrobial Activity of Co(II), Ni(II), Cu(II) and Zn(II) Complexes N- O- S Donor Ligands
Authors
1 Department of Chemistry, Agra College, Agra, U.P, IN
2 B K Birla Institute of Engineering and Technology, Pilani, Rajasthan, IN
Source
Asian Journal of Pharmaceutical Analysis, Vol 4, No 4 (2014), Pagination: 174-177Abstract
The Co(II), Ni(II), Cu(II) and Zn(II) complexes of the composition 1:1:1 molar ratio, (ML1L2) (where L1=diphenylamine-2-mercapto-2-carboxylic acid and L2=2-furyl glyoxalanthranilic acid have been synthesized and characterized by elemental analyses, H-NMR, IR, electronic spectral data and magnetic susceptibility measurements. The synthesized ligands and their metal complexes were screened for their antimicrobial activity against two bacteria Staphylococcus aureus (gram +ve) and Escherichia coli (gram -ve) and two fungi Aspergillus niger and Apergillus flavus by Serial Dilution Method. Metal complexes are more active than their ligands.Keywords
Mixed Ligand Complexes, Antimicrobial Activity.- Synthesis, Characterization and Antimicrobial Activity of Cu(II),Co(II), Ni(II) and Zn(II),Complexes with O-N Donor Ligand
Authors
1 B K Birla Institute of Engineering and Technology, Pilani, Rajasthan, IN
2 Department of Chemistry, Agra College, Agra, U.P, IN
Source
International Journal of Technology, Vol 4, No 2 (2014), Pagination: 283-286Abstract
The complexes of the type MLXn, where M= Cu(II), Co(II), Ni(II), Zn(II) and X= H2O/Cl and L is the schiff base ligand prepared from 2,4-dihydroxy-5-Acetylacetophenone and 1,4-diaminobutane have been synthesized. All complexes isolated in solid, are stable in air and characterized by the elemental analysis, metal content determination, magnetic measurements, thermo gravimetric analysis (TGA), IR, and electronic spectral data. The physicochemical data suggest a pseudo octahedral structure to Cu(II) and an octahedral for Co(II), Ni(II), and Zn(II) complexes. The ligand field parameters have been calculated and related to the electronic environment. The Schiff base and its complexes were screened for their antimicrobial activities against various bacteria and fungi.
Keywords
Metal Complexes, Schiff Base, TGA (Thermo Gravimetric Analysis) Magnetic Study, and Antimicrobial Activity.- Synthesis and Antimicrobial Activity of New 4-Thiazolidinone Derivatives Containing 2-Amino-6-Ethoxybenzothiazole
Authors
1 Department of Chemistry, B K Birla Institute of Engineering and Technology, Pilani, Jhunjhunu, Rajasthan-333031, IN
2 Department of Chemistry, Agra College, Agra, U.P, IN
Source
Asian Journal of Research in Chemistry, Vol 4, No 12 (2011), Pagination: 1945-1952Abstract
A novel series of Schiff bases 5a-j and 4-thiazolidinones 6a-j have been prepared from the building blocks 2-chloro pyridine-3-carboxylic acid [1] and 2-amino-6-ethoxy-benzothiazole [2]. All of the synthesized compounds have been confirmed by elemental analyses, IR, 1H NMR and 13C NMR spectral data. These newly synthesized compounds were screened for their antimicrobial activity. Variable and modest activity was observed against the investigated strains of bacteria and fungi, however, compound 6h revealed significant antibacterial activity against Escherichia coli. Compounds 1, 2, 3, 5c, 5g and 5h, on the other hand, revealed potent antifungal activity against Candida albicans compared to the reference drug greseofulvinKeywords
Schiff Bases, 4-Thiazolidinones, 2-Chloro Pyridine-3-Carboxylic Acid, 2-Amino-6-Ethoxybenzothiazole, Antimicrobial Activity.- Solubility of Some Pyrimidine Derivatives in Methyl-Alcohol at Different Temperatures
Authors
1 School of Applied Sciences, Singhania University, Pacheri Bari, Jhunjhunu (Raj.), IN
2 Department of Chemistry, Agra College, Agra, U.P, IN
3 Department of Chemistry, B K Birla Institute of Engineering and Technology, Pilani, Rajasthan, IN
Source
Asian Journal of Research in Chemistry, Vol 10, No 2 (2017), Pagination: 186-190Abstract
The solubility of some of Pyrimidine derivatives in methyl alcohol was measured by gravimetrical method at different temperatures (293.15 to 313.15 K) under atmospheric pressure. The solubility data were comprised with temperature by Apelblat equation. Some thermodynamic parameters such as dissolution enthalpy, and Gibbs' free energy of dissolution and entropy were evaluated from solubility data.Keywords
Pyrimidine Derivatives, Solubility Data and Thermodynamic Parameters.- Synthesis of Some Chalcone and their Heterocyclic Derivatives as Potential Antimicrobial Agents:A Review
Authors
1 School of Applied Sciences Singhania University, Pacheri Bari, Jhunjhunu (Raj.), IN
2 Department of Chemistry, Agra College, Agra, U.P, IN
3 Department of Chemistry, B K Birla Institute of Engineering and Technology, Pilani, Rajasthan, IN
Source
Asian Journal of Research in Chemistry, Vol 10, No 2 (2017), Pagination: 225-239Abstract
The Chalcone is aromatic compounds that forms the central core for different necessity of biological compounds, and are prepared by Claisen-Schmidt condensation of equimolar concentrations of arylaldehydes and acetophenones which are generally base catalysed. Chalcones are considered as the precursors of flavonoids and isoflavonoids. as the precursors the precursors of flavonoids and isoflavonoids. Chemically, chalcones are 1,3-diaryl-2-propen-1-ones in which two aromatic rings are joined by a three carbon bridge having a carbonyl moiety and α,β unsaturation. One of the most important classes of chalcones is the ring closure reactions with hydrazine, phenyl hydrazine, guanidine, urea etc. forming heterocyclic derivatives of chalcones. Both chalcones and their heterocyclic derivatives have a large number of pharmacological activities such as anti antimicrobial, antifungal, antibacterial, antioxidant, inflammatory, antitumor, anticancer, anti mitotic, anti leishmanial, anti-malarial, anti tubercular, antiviral, cytotoxic, etc. In this research paper (review) the efforts have been made to show some synthesis and biological activities of chalcones and their derivatives.Keywords
Chalcones, Claisen-Schmidt Condensation, Antimicrobial Activity, Heterocyclic Derivatives.- Synthesis and Physico Chemical Studies of Some Chalcone and Their Derivatives as Potential Antimicrobial Agents
Authors
1 School of Applied Sciences, Singhania University, Pacheri Bari, Jhunjhunu (Raj.), IN
2 Department of Chemistry, Agra College, Agra, U.P, IN
Source
Research Journal of Pharmacy and Technology, Vol 10, No 4 (2017), Pagination: 1155-1159Abstract
The Chalcone is an aromatic compound that forms the central core for various necessities of biological compounds. The Chalcone is synthesized by Claisen - Schmidt condensation of benzaldehyde derivatives with acetophenone derivatives in dilute ethanolic sodium hydroxide solution at room temperature. The structures of synthesized compounds were investigated by IR Spectroscopy, NMR Spectroscopy and Mass Spectrometry. The antimicrobial activity of the synthesized was evaluated by Filter Paper Disc diffusion Method. The compound 1b showed excellent activity against S. aureus at both concentration i.e. 500μg/ml and1000 μg/ml.Keywords
Chalcone Derivates, Antimicrobial Agents.- Synthesis, Characterization and Antimicrobial Activities of Cu(II), Ni(II) and Co(II) Complexes with N–O Donor Ligand.
Authors
1 Department of Chemistry, Agra College, Agra, U.P, IN
2 Department of Chemistry, B K Birla Institute of Engineering and Technology, Pilani, Rajasthan, IN
Source
Asian Journal of Pharmacy and Technology, Vol 4, No 4 (2014), Pagination: 205-210Abstract
The complexes of Cu (II), Ni (II) and Co (II) with a Schiff base derived from 5-bromo-3-fluorosalicylaldehyde with 4, 4'-diaminodiphenyl methane in the molar ratio 2:1 were synthesized and characterized by several techniques, including elemental analysis, IR, electronic, conductivity, LC-MS, 1H NMR, and magnetic susceptibility measurements were used to characterize the isolated ligand and its metal complexes. The ligand behaves as dibasic with N2O2 tetra dentate sites and two ligands coordinate with two metal ions to form binuclear complexes. The 1H-NMR data reveal that the Schiff base found in enol-iminic form. The binding site is nitrogen atoms of azomethine groups and oxygen atoms of the phenolic groups. The substitution in phenyl ring of the complexes produces shift in the azomethine υ(C=N) stretching vibrational frequency. The non-electrolytic behavior of complexes indicates the absence of counter ions. EPR spectra provided further information to confirm the binuclear structure. On the behalf of electronic spectral data and magnetic susceptibility measurements, the suitable geometry has been proposed for each complex. The Schiff base ligand and metal complexes were tested against four pathogenic bacteria (E. coli and K. pneumoniae) as Gram-negative, (S. aureus and B. subtilis) as Gram+positive, and pathogenic fungi (A. fumigatus) to assess their antimicrobial properties.Keywords
Anti-Microbial Activity, Schiff Base.- Do Herbal Medicines Have Potential for Managing Snake Bite Envenomation?
Authors
1 Department of Pharmacology, All India Institute of Medical Sciences, New Delhi – 110029, IN
Source
Toxicology International (Formerly Indian Journal of Toxicology), Vol 19, No 2 (2012), Pagination: 89-99Abstract
Snake envenomation is a global public health problem, with highest incidence in Southeast Asia. Inadequate health services, difficult transportation and consequent delay in antisnake venom administration are the main reasons for high mortality. Adverse drug reactions and inadequate storage conditions limit the use of antisnake venom. The medicinal plants, available locally and used widely by traditional healers, therefore need attention. A wide array of plants and their active principles have been evaluated for pharmacological properties. However, numerous unexplored plants claimed to be antidotes in folklore medicine need to be studied. The present article reviews the current status of various medicinal plants for the management of snake bite.Keywords
Antisnake venom, medicinal plants, pharmacological activity, snake bite- Synthesis, Characterization and Antimicrobial Screening of NewCyclic Imides
Authors
1 School of Applied Sciences Singhania University Pacheri Bari, Jhunjhunu (Raj.), IN
2 B K Birla Institute of Engineering and Technology, Pilani, Rajasthan, IN
Source
Research Journal of Science and Technology, Vol 9, No 4 (2017), Pagination: 691-695Abstract
The Cyclic imides and their Derivatives have been attracted significantly more attention of organic and medicinal chemists due to their antimicrobial activities. The derivatives of six member cyclic imides were synthesized by the action of glutaric anhydride with different substituted aromatic amines to obtained 4-(N-phenylcarbamoyl) butanoic acid. These intermediates undergo ring closer with acetyl chloride furnished six member cyclic imides derivatives. All these derivatives were screened for their antimicrobial activities.Keywords
Six Member Cyclic Imides, Glutarimide, 4-(N-Phenylcarbamoyl) Butanoic Acid, N-Phenyl.References
- Arun Kumar, Vinita Gupta, Sanchita Singh, Y.K. Gupta. “Synthesis of Some Chalconeand Their Heterocyclic Derivatives as Potential Antimicrobial Agents: A Review”. Asian Journal of Research in Chemistry, Vol. 10, No 02, pp 1155-1158, 2017.
- Zhang L, Hai GF, Tan Y, Xi Z, Huang MZ and Yang GF. Bioactive conformation analysis of cyclic imides as protoporphyrinogen oxidase inhibitor. Bioorg Med Chem. 2009; 17:4935-4942.
- Yogesh Kumar Gupta, Vinita Gupta, Sanchita Singh “Synthesis, Characterization and Antimicrobial activity of Pyrimidine based derivatives”. Journal of Pharmacy Research, (Elsevier) Vol. 07, No. 06, pp 491-495, 2013.
- Sondhi SM, Rani R, Roy P, Agrawal SK and Saxena AK. Microwave-assisted synthesis of N-substituted cyclic imides and their evaluation for anticancer and anti-inflammatory activities. Bioorg MedChem Lett. 2009; 19:1534-1538.
- Wang J, Zhang L, Yang GF and Zhan CG. Quantitative structure-activity relationship for cyclic imide derivatives of protoprophyrinogen oxidase inhibitors. J ChemInf Comp Sci. 2004; 44:2099-2105.
- Arun Kumar, Vinita Gupta, Sanchita Singh, Y.K. Gupta. “Synthesis and Physico Chemical Studies of Some Chalcone and Their Derivatives as Potential Antimicrobial Agents.”Research Journal of Pharmacy and Technology (RJPT) Vol. 10, Issue 04, pp178-183, 2017.
- Michalska D., Morzyk B., Bienko D.C., Wojciechowski W., Medical Hypotheses, 2000, 54(3): 472–474.
- Youngchul Lee, Ho Woong Choi, In-Joo Chin, Won H.Y. and Kim Y. S., Korea Polymer Journal, 1995, 3(2): 76-81
- Legay R., Roussel J. and Boutevin B., European Polymer Journal, 2000, 36(7): 1365-1371
- Rosana N. S. Peixoto, Giselle M. S. P. Guilhon et al., Molecules, 2013, 18: 3195-3205.
- Nicholson G. M., Spence I. and Johnston G. A. R., Elsevier, Neuropharmacology, 1985, 24(6): 461- 464
- Y.K.Gupta, Vinita Gupta, Sanchita Singh. “Synthesis, characterization and antibacterial activity of some 4-Thiazolidinones derivatives”. Asian Journal of Research in Chemistry, Vol. 05, No 9, pp 1155-1158, 2012.
- Prado S. R. T., Cechinel-Filho V., Campos-Buzzi F., Correa R., Cadena S.M.S. and Martinelli de Oliveira M. B., Z. Naturforsch, 2004, 59c: 663- 672.
- Y.K.Gupta, S.C.Agarwal, Dilip Sharma “Synthesis and biological activities of 2-Methyl-4-N-2-cyanoethyl-N-substituted benzaldehydes and their derivatives”, Asian Journal of Research in Chemistry, Vol. 5, No 2, pp 245-247, 2012.
- Mederski W.W.K.R., Baumgarth M., Germann M., KuxD.andWeitzel T., Tetrahedron Letters, 2003, 44(10), 2133-2136.
- Lee M. J., Kim S. C. and Kim J. N., Bull Korean ChemSoc, 2006, 27(1), 140-142
- Popovic-Dordevic J. B., Ivanovic M. D. and Kiricojevic V. D., Tetrahedron Letters, 2005, 46(15):2611-2614
- Rajput S. S., International Journal of Advances in Pharmacy, Biology and Chemistry, 2012, 1(2), 242-246
- Kumar R., Jain S., Jain N. and Singh M., ActaPharmaceuticalSciencia, 2008, 50: 183-188Y.
- K.Gupta, S.C.Agarwal, "Synthesis and antimicrobial activity of new 4-thiazolidinone derivatives containing 2-amino-6-ethoxybenzothiazole", Asian Journal of Research in Chemistry, Vol. 4, No 12, pp 1245-1252, 2011.
- Brian S. Furniss, Antony J. Hannaford, Peter W. G. Smith and Austin R. Tatchell, Vogel’s Textbook of Practical Organic Chemistry, Longman Scientific and Technical, John Wiley and Sons, Inc., 605 Third Avenue, New York, N Y 10158, 5th Edition, 1989: 1265-1266.
- Synthesis, Characterization and Antimicrobial Activities of Some New Amino-Pyrimidine Derivatives
Authors
1 School of Applied Sciences Singhania University Pacheri Bari, Jhunjhunu (Raj.), IN
2 Department of Chemistry, Agra College, Agra, U.P, IN
3 B K Birla Institute of Engineering and Technology, Pilani, Rajasthan, IN
Source
Research Journal of Pharmacy and Technology, Vol 12, No 1 (2019), Pagination: 167-171Abstract
In the present work, an efficient synthesis of some new Amino-Pyrimidine Derivatives has been created through response of chalcones of cyclic imides and guanidine nitrate in presence of neutral alumina. The new synthesized amino-pyrimidines showed synergistic significant activities against Candida albicans and Aspergillus nigerfungal strains.Keywords
Amino-pyrimidines, Chalcones, Antimicrobial Activity.References
- Al-Azzawi M., and Hamd A. S., Al-Anbar J. Vet. Sci., 4(2): 152-164 (2011).
- Kulveer Singh, Suman Kumari, Y.K. Gupta. “Synthesis and Antimicrobial Activity of New Pyrazoles and Chalcones Derived from Cyclic Imides.” Research Journal of Pharmacy and Technology (RJPT) Vol.10, Issue 12, pp 4479-4484, 2017. DOI: 10.5958/0974-360X.2017.00827.7
- Patil M. M. and Rajput S. S., International Journal of Pharmacy and Pharmaceutical Sciences, 6(11): 8-14 (2014).
- AL-Azzawi A. M. and Rhahman Mahdi S. A., J. of Baghdad for Sci., 10(3): 658-672 (2013).
- Arun Kumar, Vinita Gupta, Sanchita Singh, Y.K. Gupta. “Synthesis of Some Chalcone and Their Heterocyclic Derivatives as Potential Antimicrobial Agents: A Review”. Asian Journal of Research in Chemistry, Vol. 10, No 02, pp 225-239, 2017. DOI: 10.5958/0974-4150.2017.00038.4
- Amin K. M., El-masry A. H., Mohamed N. A., Awad G. E. A. and Habib B. S., Der Pharma Chemica, 5(5): 97-108 (2013).
- Yogesh Kumar Gupta, Vinita Gupta, Sanchita Singh “Synthesis, Characterization and Antimicrobial activity of Pyrimidine based derivatives”. Journal of Pharmacy Research, (Elsevier)Vol. 07, No. 06, pp 491-495, 2013.
- Gupta Vinita, Singh Sanchita and Gupta Y.K. “Synthesis and Antimicrobial Activity of some Salicylaldehyde Schiff bases of 2-aminopyridine”. Research Journal of Chemical Sciences, Vol. 03, Issue 09, pp 26-29, 2013.
- Chiriac C. I., Nechifor M. and Tanasa F., Revue Roumanie de Chimie, 52(8-9): 883-886 (2007).
- Kulveer Singh, Suman Kumari, Y.K. Gupta. “Synthesis and Antimicrobial Activity of Mono, Di and Tri Substituted Aromatic Amines and Napthyl Amine Cyclic Imides Derivatives. International Journal of Technology (IJT) Vol. 07, Issue 02, pp 85-89, 2017.
- Shaker R. M., ARKIVOC, (i): 1-44 (2012).
- Voskiene A., Mickevicius V. and Mikulskiene G., ARKIVOC, (xv): 303-314 (2007).
- Patil C. B., Mahajan S. K. and Katti S. A., Journal of Pharmaceutical Science and Research, 1(3): 11-22 (2009).
- Y.K. Gupta, Vinita Gupta, Sanchita Singh “Synthesis, characterization and antibacterial activity of some 4-Thiazolidinones derivatives”. Asian Journal of Research in Chemistry, Vol. 05, No 9, pp 1155-1158, 2012.
- Suwito H., Jumina, Mustofa, Kristanti A. N. and Puspaningsih N. N. T., Journal of Chemical and Pharmaceutical Research, 6(5):1076-1088 (2014).
- Arun Kumar, Vinita Gupta, Sanchita Singh, Y.K. Gupta. “Synthesis and Physico Chemical Studies of Some Chalcone and Their Derivatives as Potential Antimicrobial Agents.” Research Journal of Pharmacy and Technology (RJPT) Vol. 10, Issue 05, pp1155-1159, 2017.DOI: 10.5958/0974360X.2017.00208.6
- Sandhirakasu V. and Mannathuswamy G., J. of Pharmacy Research, 8(4): 548-551 (2014).
- Kulveer Singh, Suman Kumari, Y.K. Gupta. “Synthesis, Characterization and Antimicrobial Screening of New Cyclic Imides.” Research Journal of Science and Technology (RJST), Vol. 09, Issue 04, pp 691-694, 2017. DOI: 10.5958/2349-2988.2017.00117.6
- Kheder N. A., Mabkhot Y. N. and Farag A. M., ARKIVOC, (xvii): 107-116 (2008).
- Jyothi M. V., Prasad Y. R., Venkatesh P. and Sureshreddy M., Chemical Science Transactions, 1(3): 716-722 (2012).
- Ghosh R. and Das A., World Journal of Pharmacy and Pharmaceutical Sciences, 3(3): 578-595 (2014).
- Gontijo F. A., Pascon R. C., Fernandes L., Machado Jr. J., Alspaugh J. A., Vallim M. A., 70: 12–23 (2014).
- Dangar V. R., Borkhataria K. N. and Shah V. R., Sci. Revs. Chem. Commun., 4(1): 31-37 (2014).
- Himaja M., Rout P. K., Karigar A. A., Das P. and Munirajasekhar D., Universal Journal of Pharmacy, 01(01): 72-77 (2012).
- Schenone S., Zanoli S., Brullo C., Crespan E. and Maga G., Current Drug Therapy, 3: 158-176 (2008).
- Singh K., Kaur H., Chibale K., Balzarini J., Little S., Bharatam P. V., European Journal of Medicinal Chemistry, 52: 82-97 (2012).
- Y.K.Gupta, S.C.Agarwal, "Synthesis and antimicrobial activity of new 4-thiazolidinone derivatives containing 2-amino-6-ethoxybenzothiazole", Asian Journal of Research in Chemistry, Vol. 4, No 12, pp 1245-1252, 2011.
- Abd El-Moneim M., IOSR Journal of Applied Chemistry, 7(1): 67-76 (2014).
- Chaudhary A., Sharma P. K., Verma P. and Dudhe R., Analele UniversitaNii din Bucuresti – Chimie (serie noua), 20(02): 123-140 (2011).
- Singh B., Guru S. K., Kour S., Jain S. K., Sharma R., Sharma P. R., Singh S. K., Bhushan S., Bharate S. B. and Vishwakarma R. A., European Journal of Medicinal Chemistry, 70: 864-874 (2013).
- Khdur Radhiya A., International J. of Pharmaceutical Chemistry, 2(2), 2278-8700 (2013).
- Solankee A., Patel R. and Patel K., Der Pharma Chemica, 3(6): 317-324 (2011).
- Mohsin H. F., International J. of Pharmaceutical Chemistry Research, 2(1), 23-35 (2013).
- Arun Kumar, Vinita Gupta, Sanchita Singh, Y.K. Gupta. “Solubility of Some Pyrimidine Derivatives in Methyl- Alcohol at different Temperatures”. Asian Journal of Research in Chemistry, Vol. 10, No 02, pp186-190, 2017. DOI: 10.5958/0974-4150.2017.00031.1
- Theivendren P. S., Caiado R. J., Phadte V. D. and Silveira K. V., Research in Pharmacy, 2(4): 01-09 (2012).
- Al-Issa S. A., Oriental Journal of Chemistry, 30(2): 469-477 (2014).
- Tiwari U., Ameta C., Sharma S., Sharma M., Pathak A. K. and Punjabi P. B., European Chem. Bull., 2(5): 242-246 (2013).
- Antimicrobials Overuse in COVID-19: A Silent Pandemic of Antimicrobial Resistance
Authors
1 Division of RBMCH, Indian Council for Medical Research (ICMR), IN
2 Siri Institutional Area, New Delhi 110016, IN
Source
The Indian Practitioner, Vol 74, No 5 (2021), Pagination: 28-31Abstract
The COVID-19 epidemic has presented many treatment challenges to physicians due to the lack of specific effective medicines. The COVID-19 pandemic is also witnessing irrational antibiotic use. The aggressive use of several antibiotics for treatment of COVID-19, and its complications may lead to another pandemic of Antimicrobial Resistance (AMR). Limiting unnecessary antibiotic use in viral infections, like COVID-19, should be emphasized in antimicrobial stewardship programs.Keywords
Antimicrobials Overuse in COVID-19: A Silent Pandemic of Antimicrobial Resistance.References
- Ministry of Health and Family Welfare [Internet] MoHFW | Home. [Cited 12 May 2021]. Available from https://mohfw.gov.in
- World Health Organization [Internet] WHO Coronavirus (COVID-19). [Cited 12 May 2021]. Available from https://www.who.int/emergencies/diseases/novel-coronavirus-2019/question-and-answers-hub/q-a-detail/coronavirus-disease-covid-19 3. Singhal T. A Review of Coronavirus Disease-2019 (COVID-19). Indian J Pediatr. 2020 Apr;87(4):281-86.
- Nishiga M, Wang DW, Han Y, Lewis DB, Wu JC. COVID-19 and cardiovascular disease: from basic mechanisms to clinical perspectives. Nat Rev Cardiol. 2020 Sep;17(9):543-58.
- Mustafa L, Tolaj I, Baftiu N, Fejza H. Use of antibiotics in COVID-19 ICU patients. J Infect Dev Ctries. 2021;15:501-05.
- Beović B, Doušak M, Ferreira-Coimbra J, Nadrah K, Rubulotta F, Belliato M, Berger-Estilita J, Ayoade F, Rello J, Erdem H. Antibiotic use in patients with COVID-19: a ‘snapshot’ Infectious Diseases International Research Initiative (ID-IRI) survey. J Antimicrob Chemother. 2020 Nov 1;75(11):3386-90.
- McGettigan P, Roderick P, Kadam A, Pollock AM. Access, Watch, and Reserve antibiotics in India: challenges for WHO stewardship. Lancet Glob Health. 2017 Nov; 5(11):e1075-e1076.
- Iyengar K, Jain VK, Vaishya R. Pitfalls in telemedicine consultations in the era of COVID 19 and how to avoid them.Diabetes Metab Syndr. 2020 Sep-Oct;14(5):797-799.
- Lucien MAB, Canarie MF, Kilgore PE, Jean-Denis G, Fénélon N, Pierre M, Cerpa M, Joseph GA, Maki G, Zervos MJ, Dely P, Boncy J, Sati H, Rio AD, Ramon-Pardo P. Antibiotics and antimicrobial resistance in the COVID-19 era: Perspective from resource-limited settings. Int J Infect Dis. 2021 Mar;104:250-254.
- World Health Organization [Internet] Coronavirus disease (COVID-19). 2020 October 12.[Cited 12 May 2021].Available from https://www.who.int/emergencies/diseases/novel-coronavirus-2019/question-and-answers-hub/q-a-detail/coronavirus-disease-covid-19
- Mogasale VV, Saldanha P, Pai V, Rekha PD, Mogasale V. A descriptive analysis of antimicrobial resistance patterns of WHO priority pathogens isolated in children from a tertiary care hospital in India. Sci Rep. 2021 Mar 4;11(1):5116.
- Khurana S, Singh P, Sharad N, Kiro VV, Rastogi N, Lathwal A, Malhotra R, Trikha A, Mathur P. Profile of co-infections & secondary infections in COVID-19 patients at a dedicated COVID-19 facility of a tertiary care Indian hospital: Implication on antimicrobial resistance. Indian J Med Microbiol. 2021 Apr;39(2):147-153.
- World Health Organization. Bulletin of the World Health Organization. 2020; 2020;98:442-442A.
- World Health Organization [Internet] Prioritization of pathogens to guide discovery, research and developmentof new antibiotics for drug resistant bacterial infections, including tuberculosis. 2017 October
- [Cited 12 May 2021].Available from https://www.who.int/medicines/areas/rational_use/prioritization-of-pathogens/en/.
- Ganguly N. Situation Analysis: Antibiotic Use and Resistance in India. 2011 October 13. [Cited 12 May 2021]. Available from https://cddep.org/wp-content/uploads/2017/06/indiareport-web_8.pdf.
- Physico- Chemical Assessment of Tube wells Water Quality of Pilani Town District Jhunjhunu, Rajasthan, India
Authors
1 Research Scholar, Department of Chemistry, Shri Jagdishprasad Jhabarmal Tibrewala University, Jhunjhunu, Churu Road, Vidyanagari, Chudela, Rajasthan 333001, IN
2 Head Department of Chemistry, B K Birla Institute of Engineering and Technology, Pilani, Rajasthan, IN
Source
Research Journal of Science and Technology, Vol 14, No 2 (2022), Pagination: 91-94Abstract
The water has become an emotive issue with the people. The paper presents groundwater quality assessments of Pilani Town District Jhunjhunu, Rajasthan India. The water samples were collected from 10 open wells, tube wells and hand pumps in Pilani. Ground water is increasingly being sought as a source of drinking water due to the scarcity, non-availability and bacteriological pollution of surface water. This paper describes the important results of the Physico-chemical Assessment of the ground water samples of the open wells, tube wells and hand pumps of the urban areas in Pilani, District Jhunjhunu of Rajasthan. The different parameters determined are pH, TDS, fluoride, chloride, nitrate, sulphate, total alkalinity and total hardness. It has been observed that nitrate values are higher compaired to ICMR standards. Other parameters were found within desirable limits. The interesting fact is that the nitrate alone is making ground water unfit for drinking.Keywords
Water Quality, Physico-chemical parameters, Ground water of Pilani TownReferences
- Babita Kumari, Y.K. Gupta* “A Comprehensive review report on assessment of ground water quality in Jhunjhunu district of Rajasthan, India, focus on fluoride." Asian J. of Research in Chemistry, Vol. 08, issue 11, pp 701-707, 2015.
- Anil kumar Saini, Alka, Yogesh Kumar Gupta “Water Quality Analysis of Singhana in Buhana Tehsil of Jhunjhunu District (Rajasthan)” International Journal of Renewable Energy Exchange (Rex Journal) Vol. 4 Issue 03, pp 265-267, 2017.
- D.K. Sinha and A.K. Srivastava, Indian J. Environ. Hlth., 37, 205 (1995).
- Sandeep M, (2019), Study of Fluoride contamination in ground water of Manawa area of Jhunjhunu district Rajasthan – The heritage city of Shekhawati, Int. J. Chem. Sci, 9(2), 751- 756.
- A.A. Ansari, I.B. Singh and H.J. Tobschall, Indian Environ. Geol., 38, 25 (1999)
- Kaushik et al, J. of Hazardous Material, 164: 265-270 (2019).
- Manuals of Standards of Drinking Water Supply, ICMR, New Delhi, 2nd Special Report Series No. 44 (1975).
- Babita Kumari, Y.K. Gupta* “Physico-Chemical Characteristics of Underground water Quality of some villages of Jhunjhunu District of Rajasthan, India.” International Journal of Research in Chemistry and Environment, Vol. 05, issue 04, pp 95-102, 2015.
- A. Sreenivason, F.A.O. Fish Rep, 44(3), 101 (1967)
- Prasad B. Guru, Evaluation of Water Quality in Tadepalli Mandal of Guntur Distt., A.P., Nature, Environ. and Poll. Techn., 2(3) 273-276 (2003).
- Babita Kumari, Y.K. Gupta* “Stastical Assessment of Ground water Quality using Physico- Chemical Parameters in Jhunjhunu District of Rajasthan, India.” Research J. Science and Tech. Vol. 07, issue 04, pp 217-222, 2015.
- N. Kumarswamy, Poll. Res., 10, 13 (1991)
- K. Vijayram, S.R. Vyasugi, S.Chitra, and U. Asha, Poll. Res., 9, 133 (1990)
- Mahavir Prasad, (2017) Geochemical studies of fluoride & other water quality parameter of ground water of Sikar Dist. Rajasthan, Int J ChemSci, 5(2)623-629.
- Anil Kumar Saini, Alka, Yogesh Kumar Gupta “Water Quality Analysis of Singhana in Buhana Tehsil of Jhunjhunu District (Rajasthan)” International Journal of Renewable Energy Exchange (Rex Journal) Vol. 4 Issue 04, pp 345-347, 2017