Study of some Hematological Parameters in Normal Pregnancy and Pregnancy Induced Hypertension

Introduction: Pregnancy Induced Hypertension (PIH) is defined as hypertension that occurs in pregnancy for the first time after 20 weeks of gestation and disappears following delivery. It affects approximately 6-8% of all pregnancies, most often the primigravidas. It is one of the most important causes of maternal and fetal morbidity and mortality.

Material&Method: About 140 female are randomly selected with the age ranging from 18 to 45 years from the OPD, Department of Obstetrics&Gynaecology, out of which 70 pregnancy induced hypertensive female at gestational age of > 20 weeks as study group and 70 normotensive pregnant female at gestational age of > 20 weeks as control group. The control group is free from any systemic disease. Now the study group i.e. case and control group are further divided into group A, B and C respectively. The haematological analysis include Haemoglobin, Total leucocyte count, Platelet Count, RBC count, Differential Leucocyte count, Prothrombin time, activated partial thromboplastin time (aPTT), SGOT, SGPT, Serum Total protein, S. Albumin, S. Globulin and A: G Ratio.

Result: In group C there is significant difference in Haemoglobin and Total Leucocytes count (TLC) of case and control. Platelet Count there is significant difference in between case and control of group A, B and C. Serum Globulin, A/G Ratio there is significant difference in between case and control of group, B and C. PT and aPTT there is highly significant difference in between case and control of group A, B and C.

Conclusion: We found that there is a significant correlation between the Platelet Count, PT and aPTT and the severity of PIH.