Journal of Natural Remedies

Abstract

Skyrocketed numbers of autism reports with an incremental surge in its prevalence getting multiplied by four in the past decade is wary of an epidemic afoot. A randomised control trial was conducted to evaluate the effectiveness of Ayurveda polyherbal compounds and lifestyle guidelines in addition to the conventional therapies of speech therapy, occupational therapy and behavioral therapy in test group compared to their controls in the bacterial flora for the species of E. coli and Shigella done by 16 S ribosomal RNA sequencing. A clinical trial was conducted at the Out-patient and In-patient units of Vaidyaratnam P. S. Varrier Ayurveda College wherein a total of 60 ASD diagnosed children were included with a random allocation of 1:1 as test group and control group. Test group received Ayurveda poly-herbal formulations and dietary and lifestyle guidelines for 30 days along with multidisciplinary interventions for 2 months however control group received multidisciplinary therapies along with dietary and lifestyle guidelines alone for 2 months. Significant changes were obtained as results with the species of both E. coli and Shigella which was of primordial dominance before treatment has been reduced after treatment in the test group. After one month of medication in the test group much influential positive changes has occurred whereas such significance is not noted in the control group meaning that the conventional therapies of speech therapy and occupational therapy alone could not make an alteration. Polyherbal compounds of Rajanyadi choornam and Vilwadi gulika along with the dietary lifestyle guidelines and multidisciplinary interventions helps the autistic children to reduce their relative abundance for the species of E. coli and Shigella.

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