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Edwin, Aileen Rose
- Comparative Analysis of Bioactive Compounds and Anticancerous Activities in Leaf and Stem Extract of Physalis minima
Abstract Views :251 |
PDF Views:198
Authors
Affiliations
1 Molecular Diagnostics and Biomolecular Characterization Laboratory, Bannari Amman Institute of Technology, Sathyamangalam – 638401, Erode District, Tamil Nadu, IN
1 Molecular Diagnostics and Biomolecular Characterization Laboratory, Bannari Amman Institute of Technology, Sathyamangalam – 638401, Erode District, Tamil Nadu, IN
Source
Journal of Natural Remedies, Vol 20, No 1 (2020), Pagination: 42-52Abstract
Physalis minima, commonly known as native gooseberry is a perennial herb which grows mostly in the tropical regions and is used in the traditional medicines as a curative for gastric ulcers and also for respiratory tract related ailments. The leaf and stem crude extract was separated by soxhelet using chloroform as solvent followed by the phytochemical screening to identify the presence of secondary metabolites. The Fourier-transform infrared spectroscopy (FTIR) showed the presence of various functional group such as phenol, alkane, aldehyde, alkyls, amino acid, aromatic amino acids and secondary alcohol. The Gas chromatography-mass spectrometry (GC-MS) result showed the presence of total of 24 bioactive compounds in both extracts such as Heptacosane, 1-chloro, Heptacosane, Octadecanoic acid, N-hexadecanoic acid and Hexatriacontane. The extract was subjected to for its anti-cancerous activity using MTT assay which had a good result against HL60 cell line and antibacterial activities.Keywords
HL60, MTT Assay, Physalis minima, Phytochemical Screening, Soxhlet Extraction.Full Text
References
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- Antibacterial and in vitro Anticancer Study of Methanol Extracts of Clitoria ternatea Leaves
Abstract Views :309 |
PDF Views:401
Authors
Arunava Das
1,
G. Shanmuga Priya
1,
S. Soundariya
1,
P. Deepesh
1,
Aileen Rose Edwin
1,
E. Vihashinee
1,
A. Rubiga
1,
S. Megavarthini
1,
R. Eswaran
1,
J. Bindhu
1
Affiliations
1 Molecular Diagnostics & Biomolecule Characterization Lab, Department of Biotechnology, Bannari Amman Institute of Technology, Sathyamangalam – 638401, Erode, IN
1 Molecular Diagnostics & Biomolecule Characterization Lab, Department of Biotechnology, Bannari Amman Institute of Technology, Sathyamangalam – 638401, Erode, IN
Source
Journal of Natural Remedies, Vol 20, No 2 (2020), Pagination: 96-102Abstract
Clitoria ternatea is often known as butterfly pea plant by the natives and is one of the major plants used in Ayurveda and traditional medicine worldwide. It is also used in food and cosmetic industries for various purposes. In this study, methanol leaf extract of Clitoria ternatea was studied for its antibacterial and in vitro anticancer study against human promyelocytic leukemia cells (HL60). Secondary metabolites like alkaloids, phlobatannin, triterpenoids, flavonoids, lipids, steroids, terpenoids, tannins and glycosides are identified in the extract by phytochemical screening. Leaf extract showed the presence of ethers and carboxylic acid groups (GCMS analysis). The leaf extract showed resistance against Salmonella typhi. Thus, from this study it can be concluded Clitoria ternatea leaves methanol extract has bioactive compounds showing anticancer activity against HL60 cells.Keywords
Antibacterial Activity, Anticancer Activity, Clitoria ternatea, GC-MS Analysis, Phytochemical Screening, MTT Assay.Full Text
References
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- Mathew N, Anitha MG, Bala TSL, Sivakumar SM, Narmadha R, Kalyanasundaram M. Larvicidal activity of Saracaindica, Nyctanthesarbor-tristis, and Clitoria ternatea extracts against three mosquito vector species. Parasitology Research. 2009; 104(5):1017–25. https://doi.org/10.1007/s00436-008-1284-x. PMid:19039604
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- Kumar TR, Kumar S, Anju VS. Phytochemical and antibacterial activities of crude leaf and ischolar_main extracts of Clitoria ternatea varieties (Fabaceae). Journal of Pharmacognosy and Phytochemistry. 2017; 6(6):1104–8.
- Sarumathy K, Rajan MD, Vijay T, Jayakanthi J. Evaluation of phytoconstituents, nephro-protective and antioxidant activities of Clitoria ternatea. Journal of Applied Pharmaceutical Science. 2011; 1(5):164–72.
- Antimicrobial, Antioxidant and Anticancer Activity of the Ethanol Extract of Pleurotus ostreatus
Abstract Views :280 |
PDF Views:243
Authors
J. Bindhu
1,
Arunava Das
1,
E. Vihashinee
1,
A. Rubiga
1,
Aswin Edward
1,
R. Eswaran
1,
G. Shanmuga Priya
1,
S. Soundariya
1,
Aileen Rose Edwin
1
Affiliations
1 Molecular Diagnostics & Biomolecule Characterization Lab, Department of Biotechnology, Bannari Amman Institute of Technology, Sathyamangalam – 638401, Erode District, Tamil Nadu, IN
1 Molecular Diagnostics & Biomolecule Characterization Lab, Department of Biotechnology, Bannari Amman Institute of Technology, Sathyamangalam – 638401, Erode District, Tamil Nadu, IN
Source
Journal of Natural Remedies, Vol 20, No 2 (2020), Pagination: 110-115Abstract
The current study evaluates antimicrobial, antioxidant and anticancer activity of the ethanol extract of Pleurotus ostreatus. Chemical analysis showed the presence of alcohol, amides, alkanes, ether, phenol and sulphides. Most of the chemical constituents were found to be esters and carboxylic acid derivatives. The extract showed highest resistant against Bacillus cereus. P. ostreatus ethanol extract showed comparable antioxidant activity with ascorbic acid in both DPPH and FRAP method and also showed an IC50 of 39.29 μg/ml against HL60 cells.Keywords
MTT, DPPH, HL-60 Cells, FRAP, GC-MS.Full Text
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