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Yadav, Ramakant
- Conventional Therapeutic Drugs and Traditional Herbal Medicine in Prevention and Treatment of Novel Corona Virus (COVID-19): An Update
Abstract Views :114 |
Authors
Affiliations
1 Department of Neurology, Uttar Pradesh University of Medical Sciences, Saifai, Etawah – 206130, Uttar Pradesh, India, IN
1 Department of Neurology, Uttar Pradesh University of Medical Sciences, Saifai, Etawah – 206130, Uttar Pradesh, India, IN
Source
Journal of Natural Remedies, Vol 20, No 4 (2020), Pagination: 192-197Abstract
Background: Since December 2019, severe acute respiratory syndrome coronavirus to developing severe acute respiratory disease originated from Wuhan, China, and further spread rapidly all over the world except very few counties. On 30th January 2020, The WHO confirmed the epidemic as a community health crisis all over world. No drug was approved for treatment but some conventional and traditional medicinal plants are being used against COVID-19 infections. Objective: The present review is to illustrate current updates on conventional and traditional herbal medicine used for deterrent and treatment of SARS-CoV-2 infection. Methods: Search engines like Scopus, Pubmed, and World Health Organization (WHO) literature on current advances about novel coronavirus (COVID-19) were reviewed. Discussion and Conclusion: Current research data indicated that the outbreaks caused by SARS MERS and COVID-19 have produced substantial community health problems. Currently, there are no vaccines for prevention or specific treatments however it can be managed by using oxygen therapy, convalescent plasma therapy, antimalarial drugs, and broad-spectrum antiviral drugs. Many traditional herbal and Chinese medicines may be useful.Keywords
Conventional Drugs, COVID-19, Diagnosis, Traditional Herbal MedicineFull Text
References
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- Burki TK. Coronavirus in China. Lancet Respiratory Medicine. 2020. https://doi.org/10.1016/S2213- 2600(20)30056-4
- World Health Organization. WHO Director-General’s remarks at the media briefing on 2019-nCoV on 11 February 2020; 2020.
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- Sexton NR, Smith EC, Blanc H, Vignuzzi M, Peersen OB, Denison MR. Homology-based identification of a mutation in the coronavirus RNAdependent RNA polymerase that confers resistance to multiple mutagens. Journal of Virology. 2016; 90(16):7415–28. https://doi.org/10.1128/JVI.00080-16. PMid:27279608 PMCid:PMC4984655
- Emery SL, Erdman DD, Bowen MD et al. Real-time reverse transcription-polymerase chain reaction assay for SARSassociated coronavirus. Emerging Infectious Diseases. 2004; 10:311–16. https://doi.org/10.3201/eid1002.030759. PMid:15030703 PMCid:PMC3322901
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- Wang, Wu Q, Xu W, Qiao B, Wang J, Zheng H, et al. Clinical diagnosis of 8274 samples with 2019-novel coronavirus in Wuhan. medRxiv preprint; 2020. p. 1–18. https://doi. org/10.1101/2020.02.12.20022327
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- Ip VHY, Sondekoppam RV, Ozelsel TJP, Tsui BCH Coronavirus disease 2019 (COVID-19) pandemic: International variation of Personal Protective Equipment (PPE) and Infection Prevention and Control (IPC) guidelines. Anesthesia & Analgesia. 2020; 10(1213):1–6.
- Whittle JS, Pavlov I, Sacchetti AD, Atwood C, Rosenberg MS. Respiratory support for adult patients with COVID- 19. JACEP Open; 2020. p. 1–7. https://doi.org/10.1002/ emp2.12071. PMid:32427171 PMCid:PMC7228246
- Yoo JH. Convalescent plasma therapy for corona virus disease 2019: A long way to go but worth trying. Journal of Korean Medical Science. 2020 Apr 13; 35(14):e150. https:// doi.org/10.3346/jkms.2020.35.e150. PMid:32281318 PMCid:PMC7152529
- Al-Bari MAA. Targeting endosomal acidification by chloroquine analogs as a promising strategy for the treatment of emerging viral diseases. Pharmacology Research & Perspectives. 2017; 5(1):e00293 https://doi.org/10.1002/ prp2.293. PMid:28596841 PMCid:PMC5461643
- Wang M, Cao R, Zhang L, Yang X, Liu J, Xu M, et al. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro. Cell Research. 2020; 30(3):269–71. https://doi.org/10.1038/ s41422-020-0282-0. PMid:32020029 PMCid:PMC7054408
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- Zhang L, Liu Y. Potential interventions for novel coronavirus in China: A systematic review. Journal of Medical Virology. 2020; 92(5):479–90. https://doi.org/10.1002/jmv.25707. PMid:32052466 PMCid:PMC7166986
- Lee N, Chan KCA, Hui DS, Ng EK, Wu A, Chiu RW, et al. Effects of early corticosteroid treatment on plasma SARSassociated Coronavirus RNA concentrations in adult patients. Journal of Clinical Virology. 2004; 31(4):304–9. https://doi.org/10.1016/j.jcv.2004.07.006. PMid:15494274 PMCid:PMC7108318
- Ferrey AJ, Choi G, Hanna RM, Chang Y, Tantisattamo E, Ivaturi K, et al. A case of novel coronavirus disease 19 in a chronic hemodialysis patient presenting with gastroenteritis and developing severe pulmonary disease. American Journal of Nephrology. 2020; 28:1–6. https://doi.org/10.1159/000507417. PMid:32222713 PMCid:PMC7179539
- Hu W, Fu W, Wei X, Yang Y, Lu C, Liu Z. A network pharmacology study on the active ingredients and potential targets of Tripterygium wilfordii Hook for treatment of rheumatoid arthritis. Evidence-Based Complementary and Alternative Medicine. 2019; 5276865:1–16. https:// doi.org/10.1155/2019/5276865. PMid:31118961 PMCid:PMC6500618
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- Conventional Therapeutic Drugs and Traditional Herbal Medicine in Prevention and Treatment of Novel Corona Virus (COVID-19): An Update
Abstract Views :108 |
Authors
Affiliations
1 Department of Neurology, Uttar Pradesh University of Medical Sciences, Saifai, Etawah – 206130, Uttar Pradesh, India, IN
1 Department of Neurology, Uttar Pradesh University of Medical Sciences, Saifai, Etawah – 206130, Uttar Pradesh, India, IN
Source
Journal of Natural Remedies, Vol 20, No 4 (2020), Pagination: 192-197Abstract
Background: Since December 2019, severe acute respiratory syndrome coronavirus to developing severe acute respiratory disease originated from Wuhan, China, and further spread rapidly all over the world except very few counties. On 30th January 2020, The WHO confirmed the epidemic as a community health crisis all over world. No drug was approved for treatment but some conventional and traditional medicinal plants are being used against COVID-19 infections. Objective: The present review is to illustrate current updates on conventional and traditional herbal medicine used for deterrent and treatment of SARS-CoV-2 infection. Methods: Search engines like Scopus, Pubmed, and World Health Organization (WHO) literature on current advances about novel coronavirus (COVID-19) were reviewed. Discussion and Conclusion: Current research data indicated that the outbreaks caused by SARS MERS and COVID-19 have produced substantial community health problems. Currently, there are no vaccines for prevention or specific treatments however it can be managed by using oxygen therapy, convalescent plasma therapy, antimalarial drugs, and broad-spectrum antiviral drugs. Many traditional herbal and Chinese medicines may be useful.Keywords
Conventional Drugs, COVID-19, Diagnosis, Traditional Herbal MedicineFull Text
References
- Gralinski LE, Menachery VD. Return of the coronavirus: 2019-nCoV. Viruses. 2020; 12(2):E135. https://doi.org/10.3390/v12020135. PMid:31991541 PMCid:PMC7077245
- Burki TK. Coronavirus in China. Lancet Respiratory Medicine. 2020. https://doi.org/10.1016/S2213- 2600(20)30056-4
- World Health Organization. WHO Director-General’s remarks at the media briefing on 2019-nCoV on 11 February 2020; 2020.
- Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020; S0140-6736(0120):30183–5.
- Guan WJ, Ni ZY, Hu Y, Liang WH, Ou CQ, He JX, et al. Clinical characteristics of 2019 novel coronavirus infection in China. medRxiv; 2020. https://doi. org/10.1101/2020.02.06.20020974
- World Health Organization COVID-19 Corona virus Pandemic [Internet]. 2019. Available from: https://www. who.int/emergencies/diseases/novel-coronavirus-2019.
- Chan JF-W, Yuan S, Kok K-H, To KK-W, Chu H, Yang J, et al. A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster. Lancet. 2020; S0140-6736(0120):30154–9.
- Chen N, Zhou M, Dong X, Qu J, Gong F, Han Y, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: A descriptive study. Lancet. 2020; 395(10223):507–13. https:// doi.org/10.1016/S0140-6736(20)30211-7
- Sexton NR, Smith EC, Blanc H, Vignuzzi M, Peersen OB, Denison MR. Homology-based identification of a mutation in the coronavirus RNAdependent RNA polymerase that confers resistance to multiple mutagens. Journal of Virology. 2016; 90(16):7415–28. https://doi.org/10.1128/JVI.00080-16. PMid:27279608 PMCid:PMC4984655
- Emery SL, Erdman DD, Bowen MD et al. Real-time reverse transcription-polymerase chain reaction assay for SARSassociated coronavirus. Emerging Infectious Diseases. 2004; 10:311–16. https://doi.org/10.3201/eid1002.030759. PMid:15030703 PMCid:PMC3322901
- Gaunt ER, Hardie A, Claas EC et al. Epidemiology and clinical presentations of the four human coronaviruses 229E, HKU1, NL63, and OC43 detected over 3 years using a novel multiplex real-time PCR method. Journal of Clinical Microbiology. 2010; 48:2940–7. https://doi.org/10.1128/ JCM.00636-10. PMid:20554810 PMCid:PMC2916580
- Jan H, Faisal S, Khan A, Khan S, Usman H, Liaqat R, et al. COVID-19: Review of epidemiology and potential treatments against 2019 novel coronavirus. Discoveries (Craiova). 2020; 26; 8(2):e108. https://doi.org/10.15190/d.2020.5. PMid:32377559 PMCid:PMC7199242
- Li F, Li W, Farzan M, Harrison SC. Structure of SARS coronavirus spike receptor-binding domain complexed with receptor. Science. 2005; 309 (5742):1864–8. https://doi. org/10.1126/science.1116480. PMid:16166518
- Wang, Wu Q, Xu W, Qiao B, Wang J, Zheng H, et al. Clinical diagnosis of 8274 samples with 2019-novel coronavirus in Wuhan. medRxiv preprint; 2020. p. 1–18. https://doi. org/10.1101/2020.02.12.20022327
- Symptoms of novel coronavirus (2019-nCoV) | CDC [Internet]. (cited 2020 Mar 18). Available from: www.cdc. gov. 2020.
- WHO Coronavirus Disease 2019 (COVID-19). WHO. Health topic/Corona virus; 2020.
- Singhal T. A review of coronavirus disease-2019 (COVID-19). The Indian Journal of Pediatrics. 2020; 87(4):281–6. https://doi.org/10.1007/s12098-020-03263-6. PMid:32166607 PMCid:PMC7090728
- Emery SL, Erdman DD, Bowen MD, Newton BR, Winchell JM, Meyer RF, et al. Real-time reverse transcriptionpolymerase chain reaction assay for SARS- associated coronavirus. Emerging Infectious Diseases. 2004; 10:311–16. https://doi.org/10.3201/eid1002.030759. PMid:15030703 PMCid:PMC3322901
- Gaunt ER, Hardie A, Claas EC, Simmonds P, Templeton KE. Epidemiology and clinical presentations of the four human coronaviruses 229E, HKU1, NL63, and OC43 detected over 3 years using a novel multiplex real-time PCR method. Journal of Clinical Microbiology. 2010; 48:2940–7. https://doi.org/10.1128/JCM.00636-10. PMid:20554810 PMCid:PMC2916580
- Ip VHY, Sondekoppam RV, Ozelsel TJP, Tsui BCH Coronavirus disease 2019 (COVID-19) pandemic: International variation of Personal Protective Equipment (PPE) and Infection Prevention and Control (IPC) guidelines. Anesthesia & Analgesia. 2020; 10(1213):1–6.
- Whittle JS, Pavlov I, Sacchetti AD, Atwood C, Rosenberg MS. Respiratory support for adult patients with COVID- 19. JACEP Open; 2020. p. 1–7. https://doi.org/10.1002/ emp2.12071. PMid:32427171 PMCid:PMC7228246
- Yoo JH. Convalescent plasma therapy for corona virus disease 2019: A long way to go but worth trying. Journal of Korean Medical Science. 2020 Apr 13; 35(14):e150. https:// doi.org/10.3346/jkms.2020.35.e150. PMid:32281318 PMCid:PMC7152529
- Al-Bari MAA. Targeting endosomal acidification by chloroquine analogs as a promising strategy for the treatment of emerging viral diseases. Pharmacology Research & Perspectives. 2017; 5(1):e00293 https://doi.org/10.1002/ prp2.293. PMid:28596841 PMCid:PMC5461643
- Wang M, Cao R, Zhang L, Yang X, Liu J, Xu M, et al. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro. Cell Research. 2020; 30(3):269–71. https://doi.org/10.1038/ s41422-020-0282-0. PMid:32020029 PMCid:PMC7054408
- Young BE, Ong SWX, Kalimuddin S, Low JG, Tan SY, Loh J, et al. Epidemiologic features and clinical course of patients infected with SARS-CoV-2 in Singapore. JAMA. 2020; 3:10. 1001. https://doi.org/10.1001/jama.2020.3204. PMid:32125362 PMCid:PMC7054855
- Chu CM, Cheng VC, Hung IF, Wong MM, Chan KH, Chan KS, et al. Role of lopinavir/ritonavir in the treatment of SARS: Initial Virological and Clinical Findings. Thorax. 2004; 59(3):252–6. https://doi.org/10.1136/thorax.2003.012658. PMid:14985565 PMCid:PMC1746980
- Zhang L, Liu Y. Potential interventions for novel coronavirus in China: A systematic review. Journal of Medical Virology. 2020; 92(5):479–90. https://doi.org/10.1002/jmv.25707. PMid:32052466 PMCid:PMC7166986
- Lee N, Chan KCA, Hui DS, Ng EK, Wu A, Chiu RW, et al. Effects of early corticosteroid treatment on plasma SARSassociated Coronavirus RNA concentrations in adult patients. Journal of Clinical Virology. 2004; 31(4):304–9. https://doi.org/10.1016/j.jcv.2004.07.006. PMid:15494274 PMCid:PMC7108318
- Ferrey AJ, Choi G, Hanna RM, Chang Y, Tantisattamo E, Ivaturi K, et al. A case of novel coronavirus disease 19 in a chronic hemodialysis patient presenting with gastroenteritis and developing severe pulmonary disease. American Journal of Nephrology. 2020; 28:1–6. https://doi.org/10.1159/000507417. PMid:32222713 PMCid:PMC7179539
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