Karnataka Anaesthesia Journal

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Using Inj. Ondansetron in Pregnant Female during LSCS? Beware!


Affiliations
1 Departments of Anaesthesiology and Critical Care, Rural Medical College, Pravara Institute of Medical Sciences, Loni, Maharashtra, India
2 Periodontology and Implantology, Rural Medical College, Pravara Institute of Medical Sciences, Loni, Maharashtra, India
 

Prevention of postdelivery intraoperative nausea and vomiting (IONV) is one of the concerns of anesthesiologist during surgery. The main aim is to keep the patient as comfortable as possible perioperatively. Various drugs, especially prokinetics and serotonin receptor antagonists, are frequently used to overcome IONV. Among them, ondansetron is most commonly used due to lack of drug interactions and good potency. Although rare, various side effects including cardiovascular system are found with this drug. We encountered a case of symptomatic sinus bradycardia with ventricular ectopic beats after rapid intravenous ondansetron in a 31-year-old pregnant lady posted for emergency lower segment cesarean section.

Keywords

Arrhythmia, convulsion, hypoxia, LSCS, ondansetron, pregnant lady, side effects
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  • Using Inj. Ondansetron in Pregnant Female during LSCS? Beware!

Abstract Views: 129  |  PDF Views: 81

Authors

Akshaya N. Shetti
Departments of Anaesthesiology and Critical Care, Rural Medical College, Pravara Institute of Medical Sciences, Loni, Maharashtra, India
Rachita G. Mustilwar
Periodontology and Implantology, Rural Medical College, Pravara Institute of Medical Sciences, Loni, Maharashtra, India

Abstract


Prevention of postdelivery intraoperative nausea and vomiting (IONV) is one of the concerns of anesthesiologist during surgery. The main aim is to keep the patient as comfortable as possible perioperatively. Various drugs, especially prokinetics and serotonin receptor antagonists, are frequently used to overcome IONV. Among them, ondansetron is most commonly used due to lack of drug interactions and good potency. Although rare, various side effects including cardiovascular system are found with this drug. We encountered a case of symptomatic sinus bradycardia with ventricular ectopic beats after rapid intravenous ondansetron in a 31-year-old pregnant lady posted for emergency lower segment cesarean section.

Keywords


Arrhythmia, convulsion, hypoxia, LSCS, ondansetron, pregnant lady, side effects