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Atherogenic Index of Plasma among Type2 Diabetic Patients Cross-Sectional Study In Iraq


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1 Biology Department, College of Science-Mustansiriyah University, Iraq
     

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The study was carried out on (60) males previously diagnosed with diabetes mellitus type2 aged (40- 55) years with mean ± SE of age (48.46 ±5.03), who visited the Specialist Center for Endocrine and Diabetes at Baghdad province.The total cholesterol(TC) mg/dl levels were (180.90±11.68 ,209.60±14.50 ,203.10±14.65) respectively showed non significant (p˃0.05) variation in diabetic groups ,TG mg/dl levels in normal weight group (172.55±14.13) decreased significantly (p<0.01) in comparison with over weight and obese (273.95±22.83) ;(306.95±25.20) ,respectively. LDL mg/dl levels were (101.50±9.56; 110.00±12.71; 105.40±9.99) respectively showed non significant (p˃0.05) variation in diabetic groups. VLDL mg/dl in normal weight group (35.75±3.31) decreased significantly (p˂0.01) in comparison with over weight and obese (59.70±4.59); (61.30±5.03).HDL mg/dl levels were (43.20±2.01 ,42.85±3.05,40.05±3.32) respectively showed non significant (p˃0.05) variation in diabetic groups. FBG showed non-significant correlation with TC(r=-0.13),LDL(r=-0.13),TG (r=-0.12),VLDL(r=-0.15),HDL(r= 0.24). HbA1C showed positive significant (p˂0.05) correlation with TC(r= 0.25), while showed non significant correlation with TG (r= 0.10),LDL (r=0.18),VLDL (r=-0.01), HDL (r=0.16).BMI showed non-significant with TC(r=0.15),LDL(r=0.08),HDL,(r=-0.08).While positive significant (p<0.01) , correlation with TG (r=0.50), VLDL(r=0.39). The levels of AIP differ significantly (p<0.01) among diabetic groups (0.576 ± 0.04; 0.800 ± 0.06 and 0.911 ± 0.05) but over weight and obese(0.800 ± 0.06 ; 0.911 ± 0.05) were not significant (p>0.05). AIP was significantly correlated with body mass index(r = 0.25), visceral fat (r = 0.37), TC (r = 0.22), LDL (r=0.24), HDL (r = −0.72), TG (r = 0.84), glucose (r = 0.32). Positive correlation (P<0.01) with BMI(r=0.36) ;VLDL (r=0.28)(p<0.05) and negative correlation (p<0.01) with HDL-C (r=-0.32)was seen

Keywords

Diabetes mellitus ,Dyslipidemia,lipid profile,Atherogenic index of plasma(AIP).Isulin resistance(IR)
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  • Atherogenic Index of Plasma among Type2 Diabetic Patients Cross-Sectional Study In Iraq

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Authors

Dalal Abd Al-Sattar Asaad
Biology Department, College of Science-Mustansiriyah University, Iraq
Ali Shalash Sultan
Biology Department, College of Science-Mustansiriyah University, Iraq
Zaid Naji Hassan
Biology Department, College of Science-Mustansiriyah University, Iraq

Abstract


The study was carried out on (60) males previously diagnosed with diabetes mellitus type2 aged (40- 55) years with mean ± SE of age (48.46 ±5.03), who visited the Specialist Center for Endocrine and Diabetes at Baghdad province.The total cholesterol(TC) mg/dl levels were (180.90±11.68 ,209.60±14.50 ,203.10±14.65) respectively showed non significant (p˃0.05) variation in diabetic groups ,TG mg/dl levels in normal weight group (172.55±14.13) decreased significantly (p<0.01) in comparison with over weight and obese (273.95±22.83) ;(306.95±25.20) ,respectively. LDL mg/dl levels were (101.50±9.56; 110.00±12.71; 105.40±9.99) respectively showed non significant (p˃0.05) variation in diabetic groups. VLDL mg/dl in normal weight group (35.75±3.31) decreased significantly (p˂0.01) in comparison with over weight and obese (59.70±4.59); (61.30±5.03).HDL mg/dl levels were (43.20±2.01 ,42.85±3.05,40.05±3.32) respectively showed non significant (p˃0.05) variation in diabetic groups. FBG showed non-significant correlation with TC(r=-0.13),LDL(r=-0.13),TG (r=-0.12),VLDL(r=-0.15),HDL(r= 0.24). HbA1C showed positive significant (p˂0.05) correlation with TC(r= 0.25), while showed non significant correlation with TG (r= 0.10),LDL (r=0.18),VLDL (r=-0.01), HDL (r=0.16).BMI showed non-significant with TC(r=0.15),LDL(r=0.08),HDL,(r=-0.08).While positive significant (p<0.01) , correlation with TG (r=0.50), VLDL(r=0.39). The levels of AIP differ significantly (p<0.01) among diabetic groups (0.576 ± 0.04; 0.800 ± 0.06 and 0.911 ± 0.05) but over weight and obese(0.800 ± 0.06 ; 0.911 ± 0.05) were not significant (p>0.05). AIP was significantly correlated with body mass index(r = 0.25), visceral fat (r = 0.37), TC (r = 0.22), LDL (r=0.24), HDL (r = −0.72), TG (r = 0.84), glucose (r = 0.32). Positive correlation (P<0.01) with BMI(r=0.36) ;VLDL (r=0.28)(p<0.05) and negative correlation (p<0.01) with HDL-C (r=-0.32)was seen

Keywords


Diabetes mellitus ,Dyslipidemia,lipid profile,Atherogenic index of plasma(AIP).Isulin resistance(IR)



DOI: https://doi.org/10.37506/v20%2Fi1%2F2020%2Fmlu%2F194382