Research Journal of Pharmacy and Technology

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Comparison of the Effectiveness of Alcohol-based Handrub with the Combination of Chlorhexidine Gluconate, N-propanol and Hydrogen Peroxide in Dr. Soetomo General Hospital, Surabaya, Indonesia


Affiliations
1 Resident, Clinical Pathology Specialization Programme, Department of Clinical Pathology, Faculty of Medicine, Airlangga University - Dr. Soetomo Hospital, Surabaya,, Indonesia
2 Department of Clinical Pathology, Faculty of Medicine, Airlangga University - Dr. Soetomo Hospital, Surabaya,, Indonesia
     

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This study aims to analyze the ratio of the number of microorganism colonies on the surface of medical personnel’s hands before and after the use of three types of alcohol-based handrubs. This study is an experimental study with pre and post design at Dr. Soetomo Hospital in September-October 2019 with 20 respondents for each handrub used. T-test was performed to analyze the number of microbe colonies before and after the use of handrub with the combination of chlorhexidine gluconate, meanwhile Wilcoxon test was performed to analyze the number of microbe colonies before and after the use of handrub with the combination of n-propanol and hydrogen peroxide. Effectiveness analysis of the three handrubs was done using Kruskal Wallis test. There was a significant difference in the number of microbes before and after the use of handrub (p 0.05). Hands are an intermediary medium that often transmit pathogenic microorganisms that may cause HAIs. According to WHO, the usage of the three types of alcohol-based handrubs in this research can significantly decrease the number of germs. In conclusion, there was a significant difference in the number of microbial colonies before and after handrub usage. Alcohol-based handrub with the combination of chlorhexidine gluconate had the greatest effect on decreasing microbial colony count in this study. The contents of the three types of handrubs studied in this research were equally effective in decreasing microbial colony numbers on the hands of health workers.

Keywords

Healthcare acquired infections, Hand hygiene, Handrub.
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  • Comparison of the Effectiveness of Alcohol-based Handrub with the Combination of Chlorhexidine Gluconate, N-propanol and Hydrogen Peroxide in Dr. Soetomo General Hospital, Surabaya, Indonesia

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Authors

Dita Mernita Setyawati
Resident, Clinical Pathology Specialization Programme, Department of Clinical Pathology, Faculty of Medicine, Airlangga University - Dr. Soetomo Hospital, Surabaya,, Indonesia
Puspa Wardhani
Department of Clinical Pathology, Faculty of Medicine, Airlangga University - Dr. Soetomo Hospital, Surabaya,, Indonesia

Abstract


This study aims to analyze the ratio of the number of microorganism colonies on the surface of medical personnel’s hands before and after the use of three types of alcohol-based handrubs. This study is an experimental study with pre and post design at Dr. Soetomo Hospital in September-October 2019 with 20 respondents for each handrub used. T-test was performed to analyze the number of microbe colonies before and after the use of handrub with the combination of chlorhexidine gluconate, meanwhile Wilcoxon test was performed to analyze the number of microbe colonies before and after the use of handrub with the combination of n-propanol and hydrogen peroxide. Effectiveness analysis of the three handrubs was done using Kruskal Wallis test. There was a significant difference in the number of microbes before and after the use of handrub (p 0.05). Hands are an intermediary medium that often transmit pathogenic microorganisms that may cause HAIs. According to WHO, the usage of the three types of alcohol-based handrubs in this research can significantly decrease the number of germs. In conclusion, there was a significant difference in the number of microbial colonies before and after handrub usage. Alcohol-based handrub with the combination of chlorhexidine gluconate had the greatest effect on decreasing microbial colony count in this study. The contents of the three types of handrubs studied in this research were equally effective in decreasing microbial colony numbers on the hands of health workers.

Keywords


Healthcare acquired infections, Hand hygiene, Handrub.

References