Research Journal of Pharmacy and Technology

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Qualitative and Quantitative Analysis of Phytochemicals in Some Medicinal Plants of Western Himalayas


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1 Department of Life Sciences, RIMT University, Mandi Gobindgarh, Punjab, India
     

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Plants have been well known for their medicinal applications for ages and traditional medicines are still a major part of habitual treatments in different parts of the world. They are used since ancient times for treating different ailments and providing valuable drugs such as analgesics (morphine), antihypertensives (reserpine), cardiotonic (digoxin) and antimalarials (quinine and artemisinin). The discovery of medicinal plants helps in achieving the new targets in treating various diseases like cancer, malaria and neurological disorders. Herbs proved to be the only solution for treating a large number of health-related problems. Most of the recent drugs are obtained in one or another way from plants. Medicinal plants contain biologically active, naturally occurring chemical compounds known as phytochemicals which provide health benefits and protect the human cell from any type of damage. Phytochemical screenings of medicinal plants have contributed to the discovery of new drugs. In our present investigation, an attempt has been made to screen out the bioactive constituents of three selected plants of western Himalayas and further they had been subjected to quantitative analysis for estimation of different parameters.

Keywords

Medicinal plant, Phytochemicals, Biological Activity, Bioactive constituents, Western Himalayas.
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  • Rej S, Dutta M, Jamal S, Das S, Chatterjee S. Study of Phytochemical Constituents and Antibacterial Activity of Clerodendrum infortunatum. Asian Journal of Research in Pharmaceutical Sciences. 2014; 4(4): 187-195.

  • Mohanasrinvasan V, Saranya D, Sumitha V, Kalpana R, Nivetha, A. Studies on Bioactive Compounds and Therapeutic Potential of Terminalia chebula seed extract. Research Journal of Pharmacy and Technology. 2018; 11(5): 1889-1893.

  • Jaberian H, Piri K, Nazari J, Phytochemical composition and in vitro antimicrobial and antioxidant activities of some medicinal plants. Food Chemistry. 2013; 136(1): 237-244.

  • 4. Das K, Krishna P, Sarkar A, Iiangovan S, Sen S. A review on pharmacological properties of Solanum tuberosum. Research Journal of Pharmacy and Technology. 2017; 10(5): 1517-1522.

  • Gupta N, Jain U, Jain A, Lovanshi G, Mathan N, Tiwari V. Review of some important medicinal plants possesses anti-inflammatory activity. Research journal of Pharmacy and Technology. 2011; 4(10): 1506-1512.

  • Konduri M, Uppuluri K, Chintha R, Mulla S, Peruri R. In-vitro Antimicrobial Activity of Four Indigenous

  • Medicinal Plants Belonging to Bapatla, A.P. Research journal of Pharmacy and Technology. 2010; 3(2): 461-465.

  • Sarkar N, Saha B, Ghosal S. Ropidia Curculioides: Secondary metabolites and derivatives with antimycobacterial and leishmanicidal activity. Pharmacognosy Magazine. 2018; 14(59): 535-538.

  • Savithrama N, Rao M, Ankanna S. Screening of Medicinal Plants for Secondary Metabolites. Middle East Journal of Scientific Research. 2011; 8(3): 643-647.

  • Rajeshwar Y, Lalitha R. Preliminary phytochemical screening and in vitro anthelmintic effects of Acmella paniculata plant extracts. Biolife. 2013; 1(3):106- 112.

  • Ngoci S, Matasyohb J, Mwanikic C, Maina M. A Review of some Phytochemicals commonly found in Medicinal Plants. International Journal of Medicinal Plants. 2014; 105: 135-140.

  • Mathai, K. Nutrition in the Adult Years, in Krauses Food Nutrition and diet therapy. International Journal of Current Research in Chemistry and Pharmaceutical Sciences. 2014; 271: 274-275.

  • Myers N. Biodiversity hotspots Revisited. Jourmal of Bioscience. 2003; (53):916-917.

  • Samant SS, Butola SJ, Sharma A. Assessment of diversity, distribution, conservation status and preparation of management plan for medicinal plants in the catchment area of Parbati Hydroelectric Project Stage in North Western Himalayas. 2007; 4(1): 34-56.

  • Khandelwal N, Kross EK, Engelberg RA, Coe NB, Long AC, Curtis JR. Estimating the effect of palliative care interventions and advance care planning on ICU utilization: a systematic review. Critical care medicine. 2015; 43(5):1102

  • Kokate A, Li X, Jasti B. HPLC detection of marker compounds during buccal permeation enhancement studies. Journal of Pharmaceutical and biomedical analysis. 2008; 47(1): 190-194.

  • Rajesh P, Latha S, Selvamani P, Kanan R. Phytochemical analysis, in vitro antioxidant potential and GCMS of Dicranopteris linearis. Asian Journal of Pharmacological Clinical Research. 2016; 9(2): 1-6.

  • Nalini MS, Harischandra S, Tejesvi MV. Bioactive Potentials of Novel Molecules from the Endophytes of Medicinal Plants. In: Medicinally Important Biomes: Sources of Secondary Metabolites. 2018; 293-351.

  • Dahiru D, Onubiyi JA, Umaru HA. Phytochemical screening and antiulcerogenic effect of Moringa oleifera aqueous extract. African Journal of Traditional, Complementary and Alternative medicines. 2006; 3(3): 70-75.

  • Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein Measurement with the Folin Phenol Reagent. Journal of Biological Chemistry. 1951; 193(1): 265-275.

  • Lee Y, Takashi T. An improved colorometric determination of amino acids with the use of ninhydrin. Analytical Biochemistry. 1966; 14: 71-77.

  • Singleton L, Rossi A. Colorimetry of total phenolics with phosphomolybedic- phosphotungstic acid reagents. Journal of Enology and Viticulture.1965; 16: 144-158.

  • Chang C, Yang M. Estimation of total flavonoids content in propolis by two complementary colorometric methods. Food Drug Analysis. 2002; 10:178-182. 22. Harborne JB. Phytochemical Methods. Analytical Biochemistry. 1984; 21: 100-101.

  • Wadood A, Ghufran M., Jamal S, and Naeem M. Phytochemical Analysis of Medicinal Plants Occurring in Local Area of Mardan. Biochemistry and Analytical Biochemistry. 2013; 2(4): 1-4

  • Durai MV, Balamuniappan G, Geetha S. Phytochemical screening and antimicrobial activity of leaf, seed and central fruit extract of Swietenia macrophylla King. Journal of Pharmacognosy and Phytochemistry. 2016; 5(3): 181-186.

  • Keo S, Meng C, Oeung S, Nov V, Lon SA, Vichet T, Va T, Sourn M, Chea, S. Preliminary phytochemical screening of seleted medicinal plants of Cambodia. Asian Journal of Pharmacognosy. 2017; 1(4): 16-23.

  • Asha B, Krishnamurthy KH, Devaru S. Evaluation of antihyperglycaemic activity of Zingiber officinale (Ginger) in albino rats. Journal of Chemical and Pharmaceutical Research. 2011; 3(1): 452-456.

  • Lakshmi S, Padmaja G, Remani P. Antitumor effects of Isocurcumenol isolated from Curcuma zedoaria rhizomes on human and murine cancer cell. International Journal of Medicinal Chemistry. 2011; Article ID: 253962: 1-13.

  • Rahman M, Rahman A. Alamgir AN. Screening of anticancer medicinal plants for secondary metabolites. Journal of Pharmacognosy and Phytochemistry. 2016; 5(4): 100-103.

  • Lin JY, Tang CY. Determination of total phenolic and flavonoids contents in selected fruits and vegetables as well as their stimulatory effects on mouse splenocyte proliferation. Food Chemistry. 2007; 207: 140-147.

  • Gupta S, Sharma OP, Raina NS, Sehgal S. Ethno-botanical study of medicinal plants of Paddar Valley of Jammu and Kashmir, India. African Journal of Traditional, Complementary and Alternative Medicine. 2013; 10(4): 59-65.

  • Ezeonu CS, Ejikeme CM. Qualitative and Quantitative Determination of Phytochemical contents of Indigenous Nigerian softwood. New Journal of Science. 2016; 5: 1-9.

  • Mothana RA, Abdo SA, Hasson S, Althawab F, Alaghbari SA, Lindequist U. Antimicrobial, antioxidant and cytotoxic activities and phytochemical screening of some yemeni medicinal plants. Evidence based Complementary and Alternative medicine. 2010; 7(3): 323-330.

  • Ajuru MG, Williams LF, Ajuru G. Qualitative and Quantitative Phytochemical Screening of Some Medicinal Plants Used in the Niger Delta Region of Nigeria. Journal of Food and Nutritional Sciences. 2017; 5(5): 198-205.

  • Ghufran M, Jamal S, Naeem M. Phytochemical Analysis of Medicinal Plants Occurring in Local Area of Mardan. Biochemistry and Analytical Biochemistry. 2013; 2(4): 1-4.

  • Santhi KS, Sengottuvel R. Qualitative and Quantitative Phytochemical Analysis of Moringa concanensis Nimmo. International Journal of Current Microbiology and Applied Sciences. 2016; 5(1): 633-640.

  • Agbadi R, Kaukhova IE, Terninko II, Sirichenko TI. Qualitative and Quantitative Analysis of Amino acids in Morinda citrifolia (Rubiaceae). International Journal of Pharmacognosy and Phytochemical Research. 2017; 9(7): 980-984.

  • Jagadeeswari M, Hemashenpagam N. Qualitative and quantitative Phytochemical analysis of Kedrostis Foetidissima leaf extracts. International Journal of Basic and Applied Research. 2018; 8(7): 1-9.

  • Pires FB, Dolwitscha CB, Pra VD, Faccin H, Monego DL, Carvalho LM, Viana C, Lameria O, Lima FO, Bressan L, Rossa M. Qualitative and Quantitative analysis of phenolic content of Connarus angustifolius, Cecropia obtusa, Cecropia palmata, Mansoa alliacea, Thymus vulgaris based on HPLC-DAD and UHPLC-ESI-MS/MS. Revista Brasileira de Farmacognosia. 2017; 27(4): 426-433.

  • Shakir U, Jan G, Gul F, Khan S, Husna H, Sher J, Abidullah S. Phytochemistry and antibacterial activities of war affected area of banjaur agency. Pakistan Journal of Pharmacognosy and Phytochemistry. 2018; 7(3): 415-422.

  • Verma S, Mohanta T, Revathy T, Suthindhiran K, Jayasri MA. Phytochemical and pharmacological evaluation of selected plants. American Journal of Biochemistry and Biotechnology. 2013; 9(3): 291-299.

  • Celik OY, Tuna EH, Bedir E, Fazilet VS. Antimicrobial activities of methanol extracts and essential oils of Rosmarinus officinalis depending on location and seasonal variations. Food Chemistry. 2017; 100(2): 553-559.

  • Santhi KS, Sengottuvel R. Qualitative and Quantitative Phytochemical Analysis of Moringa concanensis Nimmo. International Journal of Current Microbiology and Applied Sciences. 2016; 5(1): 633-640.

  • Prabhavathi RM, Prasad MP, Jayaramu M. Studies on Qualitative and Quantitative Phytochemical Analysis of Cissus quadrangularis. Pelagia Research Library. 2016; 7(4): 11-17.

  • Amani AS, Alothman MR, Zain YM, Alqasoumi SI Alothman EA. Qualitative and quantitative analysis for Standardization of Euphorbia cuneata. Saudi Pharmaceutical Journal. 2017; 25(8): 1-11.

  • Croteau R, Toni M, Kutchan, Lewis NG. Natural Products (Analysis of some metabolites in medicinal plants): Biochemistry and Molecular Biology of Plants. American Society of Plant Physiologists. 2000; 14: 1250-1318.

  • Palacio EM, Ortiz OT, Farias GY, Alvarez LZ, Camacho NS, Sonanez-Organis JG, Lopez LO, Rodriguez JR. Determination of Amino acids in medicinal plants from Southern Sonora, Mexico. Tropical Journal of Pharmaceutical Research. 2017; 13(4): 601-606.

  • Joshi B, Patel H. In vitro Phytochemical Analysis and Anti-microbial Activity of crude extract of Bacopamonniera. International Journal of Pharmaceutical and Medical Sciences. 2014; 1(2): 128-131.

  • Gupta S, Sharma OP, Raina NS, Sehgal S. Ethno-botanical study of medicinal plants of Paddar Valley of Jammu and Kashmir, India. African Journal of Traditional, Complementary and Alternative Medicine. 2013; 10(4): 59-65.

  • Ajuru MG, Williams LF, Ajuru G. Qualitative and Quantitative Phytochemical Screening of Some Medicinal Plants Used in the Niger Delta Region of Nigeria. Journal of Food and Nutritional Sciences. 2017; 5(5): 198-205.

  • Shakir U, Jan G, Gul F, Khan S, Husna H, Sher J, Abidullah S. Phytochemistry and antibacterial activities of war affected area of banjaur agency. Pakistan Journal of Pharmacognosy and Phytochemistry. 2018; 7(3): 415-422.

  • Siraj K, Jan G, Jan GF, Khattak M, Bibi H, Ihsan M. Phytochemical Analysis, Analgesic, anti-inflammatory and anti-bacterial activities of Berberis lyceum. International Journal of Advanced Research. 2018; 6(7): 1150-1160.

  • Lydia J, Sudarsanam D. Total phenol and total tannin content of Cyperus rotundus L. and its medicinal significance. Research Journal of Pharmacy and Technology. 2012; 5(12): 1500-1502.

  • Amarakoon S, Jayasekara D. A review on garlic (Allium sativum) as a functional food. Journal of Pharmacognosy and Phytochemistry. 2017; 6(6): 1777-1780.

  • Sood S, Kumar A, Babu B, Pandey D, Kant L. Advances in Finger millet Genomics- An important Nutri-Cereal of Future. Frontiers in Plant Sciences, Plant Genetics and Genomics. 2016; 3: 1-11.

  • Kanchana PS, John AA. Pharmacognostic and Phytochemical Studies of Indigofera tirunelvelica Sanjappa. Research Journal of Pharmacy and Technology. 2020; 13(2): 923-927.

  • Asif M, Searcvy C, Zutshi A, Fischer O. An integrated management systems approach to cooperate social responsibility. Journal of Cleaner Production. 2013; 56: 7-17.


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  • Qualitative and Quantitative Analysis of Phytochemicals in Some Medicinal Plants of Western Himalayas

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Authors

Manju manjujaswal90@gmail.com
Department of Life Sciences, RIMT University, Mandi Gobindgarh, Punjab, India
Aiman Aziz
Department of Life Sciences, RIMT University, Mandi Gobindgarh, Punjab, India
Shamee Rehman
Department of Life Sciences, RIMT University, Mandi Gobindgarh, Punjab, India

Abstract


Plants have been well known for their medicinal applications for ages and traditional medicines are still a major part of habitual treatments in different parts of the world. They are used since ancient times for treating different ailments and providing valuable drugs such as analgesics (morphine), antihypertensives (reserpine), cardiotonic (digoxin) and antimalarials (quinine and artemisinin). The discovery of medicinal plants helps in achieving the new targets in treating various diseases like cancer, malaria and neurological disorders. Herbs proved to be the only solution for treating a large number of health-related problems. Most of the recent drugs are obtained in one or another way from plants. Medicinal plants contain biologically active, naturally occurring chemical compounds known as phytochemicals which provide health benefits and protect the human cell from any type of damage. Phytochemical screenings of medicinal plants have contributed to the discovery of new drugs. In our present investigation, an attempt has been made to screen out the bioactive constituents of three selected plants of western Himalayas and further they had been subjected to quantitative analysis for estimation of different parameters.

Keywords


Medicinal plant, Phytochemicals, Biological Activity, Bioactive constituents, Western Himalayas.

References