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Preliminary Phytochemical Screening and Infra-radiation Test of Crude the Leaves of Nothophanax Scutellarium Merr., Moringa Oleifera and Piper Betle L.
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Biodiversity in Indonesia is home to medicinal plants in the world, including Nothopanax scutellarium Merr., Moringa oliefera Lam., Piper betle L. Several researchers have examined the active compounds contained in these plants. This study focused on preliminary phytochemistry and FTIR analysis of leaf extracts of Nothopanax scutellarium Merr., Moringa oliefera Lam., Piper betle L. Phytochemicals were extracted with ethanol 70% by maceration. The results showed that the active compounds of flavonoids, steroids, tannins, phenols, saponins, and alkaloids were present in the three leaves. FTIR analysis observed the main peak at wavenumber 3623.44 cm-1 in the mangkokan leaf extract, wavenumber 3690.64 cm-1 in the moringa leaf extract, and wavenumber 3683.89 cm-1 in the piper betle leaf extract. All of which showed the O-H phenol functional group.
Keywords
FTIR, Moringa oliefera, Nothopanax scutellarium Merr., Piper betle L., secondary metabolites.
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- Elfahmi, Woerdenbag HJ, Kayser O. Jamu: Indonesian traditional herbal medicine towards rational phytopharmacological use. J Herb Med [Internet]. 2014; 4(2):51–73. Available from: http://dx.doi.org/10.1016/j.hermed.2014.01.002
- Dalimarta S. Atlas tumbuhan obat Indonesia. XI. Jakarta: Trubus Agriwidya; 2008. 87–88 p.
- LPPM IPB. Sehat alami dengan herbal. Hardiman I, editor. Jakarta: Gramedia; 2014. 266 p.
- Arai K, Nugraha Abdullah I, Okumura H. Identification of Ornamental Plant Functioned as Medicinal Plant based on Redundant Discrete Wavelet Transformation. Int J Comput Appl. 2013; 61(1):34–8.
- Tantiado RG. Survey on Ethnopharmacology of Medicinal Plants in Iloilo, Philippines. 2012; 4(4):11–26.
- Ong HC, Nordiana M. Malay ethno-medico botany in Machang, Kelantan, Malaysia. Fitoterapia. 1999; 70(5):502–13.
- Eden WT, Buanasari, Shihabuddin, Badahdah NK. Aktivitas Antioksidan Ekstrak Metanol Daun Mangkokan (Polyscias Scutellaria (Burn.F.)Fosberg). Media Farm Indones. 2016; 11(2):1126–35.
- Herawati D. Studi Makroskopis, Mikrokopis, Dan Skrining Fitokimia daun Nothopanax scutrllarium Merr. Airlangga; 2004.
- Revina M, Yuliani R, Putri M, Hulu W, Sinaga A, Lestari S, et al. Efektivitas Ekstrak Daun Mangkokan Terhadap Penyembuhan Luka Bakar Pada Tikus. Sci J. 2018; 7(2):166–72.
- Vinoth B, Manivasagaperumal R, Balamurugan S. Phytochemical Analysis and Antibacterial Activity of Moringa Oleifera Lam. Int J Res Biol Sci. 2012; 2(3):98–102.
- Bhattacharya A, Tiwari P, Sahu PK, Kumar S. A Review of the Phytochemical and Pharmacological Characteristics of Moringa oleifera. Pharm Bioallied Sci. 2018; 10(4):181–91.
- Panchal M, Shah B, Murti K, Shah M. Phytochemical investigation and antidiabetic activity studies of Moringa oliefera roots. Res J Pharmacol Pharmacodyn. 2011; 3(5):268-277–277.
- Nucahyati E. Khasiat Dahsyat Daun Kelor. I. Nurjannah, editor. Jakaria: Jendela Sehat, Jakarta; 2014.
- Stohs SJ, Hartman MJ. Review of the safety and efficacy of Moringa oleifera. Phyther Res. 2015; 29(6):796–804.
- Abubakar I, Usman A. Phytochemical and antibacterial investigations of moringa (Moringa oleifera) leaf extract on selected bacterial pathogens. J Microbiol Antimicrob. 2016; 8(5):28–33.
- Onsare JG, Arora DS. Antibiofilm potential of flavonoids extracted from Moringa oleifera seed coat against Staphylococcus aureus, Pseudomonas aeruginosa and Candida albicans. Aplplied Microbiol. 2014; 313–25.
- Arambewela L, Kumaratunga KGA, Dias K. StudieTs on Piper Betle of Sri Lanka. J Natn Sci Found Sri Lanka. 2005; 33(2):133–9.
- Moeljanto RD, Mulyono. Khasiat dan Manfaat Daun Sirih. 1st ed. Tangerang: Agromedia Pustaka, Jakarta; 2013.
- Kaveti B, Tan L, Kuan TS, Baig M. Antibacterial Activity Of Piper Betel Leaves. J Pharm Teach. 2011; 2(3):129–32.
- Dwivedi V, Tripathi S. Review study on potential activity of Piper betle. J Pharmacogn Phytochem. 2014; 3(4):93–8.
- Effa, Puetri NR. Pengaruh Pemberian Ekstrak Daun Sirih (Piper betle L.) terhadap Pertumbuhan Staphylococcus aureus Isolat dari Penderita Faringitis. SEL. 2015; 2(2):57–65.
- Saini S, Nanda S, Dhiman A. Elemental analysis in Piper betle linn. and Jatropha gossypifolia linn. leaves: Biosafety studies. Res J Pharm Technol. 2018; 11(11):5078–82.
- Harborne JB. Phytochemical Methods. Phytochemical Methods. 1984.
- Madike LN, Takaidza S, Pillay M. Preliminary Phytochemical Screening of Crude Extracts from the Leaves, Stems, and Roots of Tulbaghia violacea. Int J Pharmacogn Phytochem Res. 2017; 9(10):1300–8.
- T T, Rajasekar A, Doss V, Ravichandran D. Preliminary Phytochemical Screening of Different Solvent Mediated Medicinal Plant Extracts Evaluated. Int Res J Pharm. 2015; 6(4):246–8.
- Nurasikin C, Marlina, Idroes R, Soraya C, Djufri. Identification of Secondary Metabolite of Laban Leaf Extract (Vitex Pinnata L) From Geothermal Areas and Non-Geothermal of Agam Mountains In Aceh Besar, Aceh Province, Indonesia. Rasayan. 2020; 13(1):18–23.
- Pinnamaneni R. Preliminary phytochemical investigation of peel of pomegranate punica granatum L. Res J Pharm Technol. 2018; 11(8):3609–13.
- Mahadeva Rao US, Shanmuga Sundaram C, Sivakumar J. Isolation and characterization of phytochemical constituents and its antibacterial activity of brassica oleracea var acephala. Res J Pharm Technol. 2019; 12(1):297–302.
- Nurasikin CA, Marlina, Idroes R, Soraya C, Djufri. Identification of Secondary Metabolite using Phytochemical and Infra-Radiation Test on the Leaves of Vitex pinnata found in the Seulawah Agam mountain region of Aceh. Res J Pharm Technol. 2019; 12(11):5247–50.
- M. V, B. S, V. T. Phytochemical Analysis, Antibacterial Activity, FTIR and GCMS Analysis of Ceropegia juncea Roxb. Int J Pharmacogn Phytochem Res. 2018; 9(07):914–20.
- Silverstein RM, Francis X W, Kiemle DJ. Spectrometric Identification of Organic Compounds. Seventh. John Wiley & Sons, Inc. United State: John Wiley & Sons, Inc; 2005. 550 p.
- Housheh S, Trefi S, Chehna MF. Identification and Characterization of Prasugrel Degradation Products by GC/MS, FTIR and 1 H NMR. Asian J Pharm Anal. 2017; 7(2):55.
- Padmavathi Y, Anjali A, Babu NR, Kumar PR. Development and validation of new FTIR method for quantitative analysis of gliclazide in bulk and pharmaceutical dosage forms. 2017; 10(June):377–82.
- Jangde R, Singhour R, Daharwal S. Compatibility Studies Between Gatifloxacin and Pharmaceutical Excipients through Differential Scanning Calorimetry and Infra-Red Spectroscopy. Res J Pharm Dos Form Technol. 2010; 2(1):103–6.
- Shirsat MK, Gupta SK, Vaya R, Dwivedi J, Singhvi IJ, Ashawat MS, et al. Chemometric study of herbal extracts of Calotropis gigantea Linn. by FT-IR spectroscopy. Res J Pharm Technol. 2011; 4(7):1052–4.
- AL-Azawi AH, Salih WY, Hassan ZH. Phytochemical and Antioxidant Activity of (Arachis hypogaea L.) Skin Extract Scultiv Atedin Iraq. Res J Pharm Technol. 2017; 10(11):3721.
- A.O. A, T.E. F. Antimicrobial Activities and Phytochemical Analysis of Moringa oleifera Leaves on Staphylococus aureus and Streptococcus species. Am J Phytomedicine Clin Ther. 2015; 3(10):643–53.
- Patel N, Patel P, Patel D, Desai S, Meshram D. Phytochmical Analysis and Antibacterial Activity of Moringa Oleifera. 2014; 4(2):29–36.
- Sanusi SB, Mainasara MM, Maishanu HM, Saidu N, Dirisu H. Antimicrobial Activities and Phytochemical Investigation of Moringa Oleifera Lam. Leaf Extracts. 2017; 4(April):9–14.
- Harjanti DW, Ciptaningtyas R, Wahyono F. Phytochemical properties and antibacterial activity of Ageratum conyzoides, Piper betle, Muntinga calabura and Curcuma domestica against mastitis bacteria isolates. In: International Conference of Animal Science and Technology (ICAST). 2019. p. 1–5.
- Jayalakshmi B, Raveesha KA, Murali M, Amruthesh KN. Phytochemical, antibacterial and antioxidant studies on leaf extracts of Piper Betle L. Int J Pharm Pharm Sci ISSN-. 2015; 7(10):23–9.
- Syahidah A, Saad CR, Hassan MD, Rukayadi Y, Norazian MH, Kamarudin MS. Phytochemical Analysis, Identification and Quantification of Antibacterial Active Compounds in Betel Leaves, Piper betle Methanolic Extract. Pakistan J Biol Sci [Internet]. 2017; 20(2):70–81. Available from: http://dx.doi.org/10.3923/pjbs.2017.70.81
- Avijit B, Zerin T. Comparative Phytochemical and Antibacterial Properties of Piper betle Leave Extracts from Barguna and Moheshkhali, Bangladesh. 2020; 14(2):125–32.
- Sparg SG, Jäger AK, Van Staden J. The effect of cultivation and plant age on the pharmacological activity of Merwilla natalensis bulbs. South African J Bot. 2005; 71(2):191–6.
- Taylor JLS, van Staden J. The effect of age, season and growth conditions on anti-inflammatory activity in Eucomis autumnalis (Mill.) Chitt. Plant extracts. Plant Growth Regul. 2001; 34(1):39–47.
- Akinmoladun AC, Ibukun EO, Afor E, Obuotor EM, Farombi EO. Phytochemical constituent and antioxidant activity of extract from the leaves of Ocimum gratissimum. Sci Res Essays. 2007; 2(5):163–6.
- Syafrinal, Afrizal, Mai E. Isolation and elucidation structure of stigmasterol glycoside from Nothopanax scutellarium Merr leaves. J Chem Pharm Res [Internet]. 2015; 7(12):763–5. Available from: http://www.jocpr.com/articles/isolation-and-elucidation-structure-of-stigmasterol-glycoside-from-nothopanax-scutellarium-merr-leaves.pdf
- Cruz-Espinoza JE, Orduña-Díaz A, Rosales-Perez M, Zaca-Morán O, Delgado-Macuil R, Gayou VL, et al. FTIR analysis of phenolic extracts from Moringa oleifera leaves. J Biom Biostat. 2012; 11:2802.
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