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Influence of Dietary Molecules on Human Health: Whey Proteins


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1 Department of Biotechnology and Department of Life Sciences, Graphic Era (Deemed to be) University, Dehradun, Uttarakhand,, India
     

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Whey protein is one of the major sources of essential proteins which is being used widely now days for maintaining a healthy life style and to meet the daily protein requirement. In order to maintain a healthy body weight, regular exercise accompanied with a healthy diet is very important, and whey protein is a perfect source of fulfilling the protein requirements of the body. Whey is obtained majorly from milk which is formed by the production of cheese. Milk is the major source of whey as it comprises 20% of the total constituent of milk. Whey protein is a high-quality protein with a rich amino acid profile. It contains the broad spectrum of amino acids that includes essential amino acids (EAAs) and branched-chain amino acids (BCAAs) which are important in the growth and repair of tissues. Leucine, Isoleucine and Valine are the amino acids that play a major role in BCAA in protein synthesis and has recently been identified as playing role in muscle building and increase in the hormonal growth. It is easy to digest as compared to other components of milk like casein and has no fat content in it which makes it possible to help in gaining lean muscle mass in the body. These are one of the many advantages of consuming whey for which its demand in the market is rising. .Despite numerous advantages it can show some side effects like kidney problems, indigestion, bloating, etc. So it is advisable to consume it after consulting with a physician or some health expert in a specific dosage for a period of time. This review article gives a brief explanation of the role of whey proteins present in milk.

Keywords

Whey protein, milk, amino acids, fat, casein.
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  • Zhao L, Huang S, Cai X, Hong J, Wang S. A specific peptide with calcium chelating capacity isolated from whey protein hydrolysate. Journal of Functional Foods 2014; 10: 46–53.doi.10.1016/j.jff.2014.05.013.
  • Walsh H, Cheng J, Guo M. Effects of carbonation on probiotic survivability, physicochemical, and sensory properties of milk-based symbiotic beverages. Journal of Food Science 2014; 79(4): 604–613. Doi.10.1111/1750-3841.12381.
  • Liu X, Jiang D, Peterson DG. Identification of bitter peptides in whey protein hydrolysate. Journal of Agricultural and Food Chemistry 2014; 62(25), 5719–5725. doi: 10.1021/jf4019728. Epub 2013 Sep 25.
  • Lollo PCB, Amaya-Farfan J, Faria IC, Salgado JVV, Chacon-Mikahil MPT, Cruz AG, Oliveira CAF, Montagner PC, Arruda M. Hydrolyzed whey protein reduces muscle damage markers in Brazilian elite soccer players compared with whey protein and maltodextrin. A twelve-week in-championship intervention. International Dairy Journal 2014; 34(1): 19–24. doi.org/10.1016/j.idairyj.2013.07.001.
  • Paddon-Jones D, Leidy H. Dietary protein and muscle in older persons. Current Opinion in Clinical Nutrition and Metabolic Care 2014; 17(1): 5–11. doi: 10.1097/MCO.0000000000000011.
  • Power O, Fernández A, Norris R, Riera FA, FitzGerald RJ. Selective enrichment of bioactive properties during ultrafiltration of a tryptic digest of β-lactoglobulin. Journal of Functional Foods 2014; 9: 38–47. doi.org/10.1016/j.jff.2014.04.002.
  • Witard OC, Jackman SR, Breen L, Smith K, Selby A, Tipton KD. Myofibrillar muscle protein synthesis rates subsequent to a meal in response to increasing doses of whey protein at rest and after resistance exercise. Am J Clin. Nutr 2014; 99:86–95. doi: 10.3945/ajcn.112.055517. Epub 2013 Nov 20.
  • Trommelen J, van Loon LJ. Pre-sleep protein ingestion to improve the skeletal muscle adaptive response to exercise training. Nutrients 2016; 8:763. doi: 10.3390/nu8120763.
  • Snijders T, Res PT, Smeets JS, van Vliet S, van Kranenburg J, Maase K, Kies AK, Verdijk LB, van Loon LJ. Protein ingestion before sleep increases muscle mass and strength gains during prolonged resistance-type exercise training in healthy young men. J. Nutr 2015; 145:1178–1184. doi: 10.3945/jn.114.208371.
  • Moore DR, Volterman KA, Obeid J, Offord EA, Timmons BW. Post exercise protein ingestion increases whole body net protein balance in healthy children. J Appl Physiol 2014; 117:1493–1501. doi: 10.1152/japplphysiol.00224.2014.
  • Pasiakos SM, Lieberman HR, McLellan TM. Effects of protein supplements on muscle damage, soreness and recovery of muscle function and physical performance: A systematic review Sports Med 2014; 44:655–670. doi: 10.3389/fnut.2018.00083.
  • Gillen JB, Trommelen J, Wardenaar FC, Brinkmans NY, Versteegen JJ, Jonvik KL, Kapp C, de Vries J, van den Borne JJ, Gibala MJ et al. Dietary protein intake and distribution patterns of well-trained Dutch athletes. Int J Sport Nutr Exerc Metab 2016:1–23. doi: 10.1123/ijsnem.2016-0154.
  • Gathercole RJ, Sporer BC, Stellingwerff T, Sleivert GG. Comparison of the capacity of different jump and sprint field tests to detect neuromuscular fatigue. J Strength Cond Res 2015; 29:2522–2531. doi: 10.1519/JSC.0000000000000912..
  • Kikuchi N, Yoshida S, Okuyama M, Nakazato K. The Effect of High-Intensity Interval Cycling Sprints Subsequent to Arm-Curl Exercise on Upper-Body Muscle Strength and Hypertrophy. J Strength Cond Res 2016; 30(8):2318–23. doi: 10.1519/JSC.0000000000001315.
  • Wilkinson M. Distinguishing between statistical significance and practical/clinical meaningfulness using statistical inference. Sports Med 2014; 44:295–301. doi: 10.1007/s40279-013-0125-y.
  • Nuclei F, Larumbe-Zabala E. Effects of Whey Protein Alone or as Part of a Multi-ingredient Formulation on Strength, Fat-Free Mass, or Lean Body Mass in Resistance-Trained Individuals: A Meta-analysis. Sports medicine (Auckland, NZ) 2016; 46(1):125–133. doi: 10.1007/s40279-015-0403-y.
  • Trommelen J, Holwerda AM, Kouw IW, Langer H, Halson SL, Rollo I, Verdijk LB, van Loon LJ. Resistance exercise augments postprandial overnight muscle protein synthesis rates. Med Sci Sports Exerc 2016; 48:2517–2525. doi: 10.1249/MSS.0000000000001045.
  • Bell KE, Von Allmen MT, Devries MC, Phillips SM. Muscle disuse as a pivotal problem in Sarcopenia related muscle loss and dysfunction. J Frailty Aging 2016; 5(1):33–41. doi: 10.14283/jfa.2016.78.
  • Gathercole R, Sporer B, Stellingwerff T, Sleivert G. Alternative countermovement-jump analysis to quantify acute neuromuscular fatigue. Int. J Sports Physiol Perform 2015; 10:84–92. doi: 10.1123/ijspp.2013-0413
  • Gathercole R, Sporer B, Stellingwerff T. Countermovement jump performance with increased training loads in elite female rugby athletes. Int J Sports Med 2015; 36:722–728. doi: 10.1055/s-0035-1547262.
  • Kato H, Miura K, Nakano S, Suzuki K, Bannai M, Inoue Y. Leucine-enriched essential amino acids attenuate inflammation in rat muscle and enhance muscle repair after eccentric contraction. Amino Acids 2016; 48:2145–2155. doi: 10.1007/s00726-016-2240-1.
  • Kassem JM. Future Challenges of Whey Proteins. Int J Dairy Sci 2015; 10: 139–159. doi: 10.3923/ijds.2015.139.159
  • Brandelli A, Daroit DJ, Corrêa APF. Whey as a source of peptides with remarkable biological activities. Food Research International 2015; 73: 149–161. doi.org/10.1016/j.foodres.2015.01.016.
  • Bruck WM, Gibson GR, Brück TB. The effect of proteolysis on the induction of cell death by monomeric alpha-lactalbumin. Biochimie 2014; 97: 138–143. doi.org/10.1016/j.biochi.2013.10.007.
  • Khazrai YM, Defeudis G, Pozzilli P. Effect of diet on type 2 diabetes mellitus: A review. Diabetes/Metabolism Research and Reviews 2014; 30(1): 24–33. PMCID: PMC5426415.
  • Tong X, Li W, Xu JY, Han S, Qin LQ. Effects of whey protein and leucine supplementation on insulin resistance in non-obese insulin-resistant model rats. Nutrition (Burbank, Los Angeles County, Calif.) 2014; 30(9): 1076–1080. doi: 10.1016/j.nut.2014.01.013.
  • Curtis E, Litwic A, Cooper C, Dennison E. Determinants of Muscle and Bone Aging. J Cell Physiol 2015; 230(11):2618–25. doi: 10.1002/jcp.25001.
  • Farsijani S, Morais JA, Payette H, Gaudreau P, Shatenstein B, Gray-Donald K, et al. Relation between mealtime distribution of protein intake and lean mass loss in free-living older adults of the NuAge study. Am J Clin Nutr 2016; 104(3):694–703. doi: 10.3945/ajcn.116.130716.
  • Devries MC, Phillips SM. Creatine supplementation during resistance training in older adults-a metaanalysis. Med Sci Sports Exerc 2014; 46(6):1194–203. doi: 10.1249/MSS.0000000000000220.
  • Tomlinson PB, Joseph C, Angioi M. Effects of vitamin D supplementation on upper and lower body muscle strength levels in healthy individuals. A systematic review with meta-analysis. J Sci Med Sport 2015; 18(5):575–80. doi: 10.1016/j.jsams.2014.07.022.
  • Murphy CH, Oikawa SY, Phillips SM. Dietary protein to maintain muscle mass in aging: A case for permeal protein recommendations. J frailty aging 2016; 5(1):49–58. doi: 10.14283/jfa.2016.80.
  • Bell KE, Seguin C, Parise G, Baker SK, Phillips SM. Day-to-Day Changes in Muscle Protein Synthesis in Recovery From Resistance, Aerobic, and High-Intensity Interval Exercise in Older Men. The journals of gerontology Series A, Biological sciences and medical sciences. 2015; 70(8):1024–9. doi: 10.1093/gerona/glu313.
  • Hwang CL, Yoo JK, Kim HK, Hwang MH, Handberg EM, Petersen JW, et al. Novel all-extremity high intensity interval training improves aerobic fitness, cardiac function and insulin resistance in healthy older adults. Exp Gerontol 2016; 82:112–9. doi: 10.1016/j.exger.2016.06.009.
  • Verreijen AM, Verlaan S, Engberink MF, Swinkels S, de Vogel-van den Bosch J, Weijs PJ. A high whey protein-, leucine-, and vitamin D-enriched supplement preserves muscle mass during intentional weight loss in obese older adults: a double-blind randomized controlled trial. Am J Clin Nutr. 2015; 101(2):279– 86. doi: 10.3945/ajcn.114.090290.
  • Rondanelli M, Klersy C, Terracol G, Talluri J, Maugeri R, Guido D, et al. Whey protein, amino acids, and vitamin D supplementation with physical activity increases fat-free mass and strength, functionality, and quality of life and decreases inflammation in sarcopenic elderly. Am J Clin Nutr. 2016; 103(3):830–40. doi: 10.3945/ajcn.115.113357.

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  • Influence of Dietary Molecules on Human Health: Whey Proteins

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Authors

Kumari Rashmi
Department of Biotechnology and Department of Life Sciences, Graphic Era (Deemed to be) University, Dehradun, Uttarakhand,, India
Mehak Gupta
Department of Biotechnology and Department of Life Sciences, Graphic Era (Deemed to be) University, Dehradun, Uttarakhand,, India
Shreyoshi Tarapdar
Department of Biotechnology and Department of Life Sciences, Graphic Era (Deemed to be) University, Dehradun, Uttarakhand,, India
Megha Duggal
Department of Biotechnology and Department of Life Sciences, Graphic Era (Deemed to be) University, Dehradun, Uttarakhand,, India
Shubham Tyagi
Department of Biotechnology and Department of Life Sciences, Graphic Era (Deemed to be) University, Dehradun, Uttarakhand,, India
Harmanpreet Kaur
Department of Biotechnology and Department of Life Sciences, Graphic Era (Deemed to be) University, Dehradun, Uttarakhand,, India
Priyank Vyas
Department of Biotechnology and Department of Life Sciences, Graphic Era (Deemed to be) University, Dehradun, Uttarakhand,, India
Amit Gupta
Department of Biotechnology and Department of Life Sciences, Graphic Era (Deemed to be) University, Dehradun, Uttarakhand,, India

Abstract


Whey protein is one of the major sources of essential proteins which is being used widely now days for maintaining a healthy life style and to meet the daily protein requirement. In order to maintain a healthy body weight, regular exercise accompanied with a healthy diet is very important, and whey protein is a perfect source of fulfilling the protein requirements of the body. Whey is obtained majorly from milk which is formed by the production of cheese. Milk is the major source of whey as it comprises 20% of the total constituent of milk. Whey protein is a high-quality protein with a rich amino acid profile. It contains the broad spectrum of amino acids that includes essential amino acids (EAAs) and branched-chain amino acids (BCAAs) which are important in the growth and repair of tissues. Leucine, Isoleucine and Valine are the amino acids that play a major role in BCAA in protein synthesis and has recently been identified as playing role in muscle building and increase in the hormonal growth. It is easy to digest as compared to other components of milk like casein and has no fat content in it which makes it possible to help in gaining lean muscle mass in the body. These are one of the many advantages of consuming whey for which its demand in the market is rising. .Despite numerous advantages it can show some side effects like kidney problems, indigestion, bloating, etc. So it is advisable to consume it after consulting with a physician or some health expert in a specific dosage for a period of time. This review article gives a brief explanation of the role of whey proteins present in milk.

Keywords


Whey protein, milk, amino acids, fat, casein.

References