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Julius, A.
- Effect of Hesperidin for its Anti-Proliferative Activity on Liver Cancer and Cardio Vascular Diseases
Abstract Views :137 |
PDF Views:3
Authors
A. Julius
1,
Ramachandran Vedasendiyar
2,
Archana Devakannan
3,
Sujatha Rajaraman
4,
Balamurugan Rangasamy
5,
V. Saravanan
1
Affiliations
1 Department of Biochemistry, Sree Balaji Dental College and Hospital, Bharath University, Pallikaranai, Chennai-600 100, IN
2 Department of Biochemistry, Bharath University and Lab Incharge, Public Health and Preventive Medicine, Govt of Tamilnadu, IN
3 Public Health and Preventive Medicine, IN
4 Ashok Nagar, Tamilnadu, IN
5 Shree Manakula Vinayagar Medical College and Hospital, Pondicherry, IN
6 Department of Biochemistry, Sree Balaji Dental college and Hospital, Bharath University, Pallikaranai, Chennai-600 100, IN
1 Department of Biochemistry, Sree Balaji Dental College and Hospital, Bharath University, Pallikaranai, Chennai-600 100, IN
2 Department of Biochemistry, Bharath University and Lab Incharge, Public Health and Preventive Medicine, Govt of Tamilnadu, IN
3 Public Health and Preventive Medicine, IN
4 Ashok Nagar, Tamilnadu, IN
5 Shree Manakula Vinayagar Medical College and Hospital, Pondicherry, IN
6 Department of Biochemistry, Sree Balaji Dental college and Hospital, Bharath University, Pallikaranai, Chennai-600 100, IN
Source
Research Journal of Pharmacy and Technology, Vol 10, No 1 (2017), Pagination: 307-308Abstract
Objective is to study the Plants that have served as a rich source of medicine including anti-cancer drugs. Research has shifted from the study of using extracts of whole or parts of plants to single active principles. Identification of cytotoxic agents led to the development of anticancer therapeutics with significant success but having severe side effects. Recent advances in understanding the molecular basis of cancer and development of high thorough screening methodologies have led to the discovery of novel therapies in the form of target-based drugs. Plant metabolites like flavonoids have fewer side effects and predominantly act by their capacity to scavenge free radicals, enzyme inhibition, and/or antiproliferative activity. Hesperidin is a biologically active flavonoid, is commonly found in citrus fruits and is used in Chinese medicine. It has been shown to have several useful pharmacological properties including blood lipid lowering activity.Keywords
Hesperidin, Citrus Fruits, Chemopreventive Activity, Liver Cancer, Reducing Cholesterol.
- In Vitro Antioxidant effect of Green Tea Polyphenol Epigallocatechin-3-Gallate (EGCG) in Protecting Cardiovascular Diseases
Abstract Views :304 |
PDF Views:0
Authors
K. Pramila
1,
A. Julius
2
Affiliations
1 Bharathiyar University, Coimbatore, IN
2 Department of Biochemistry, Sree Balaji Dental College and Hospital, Pallikaranai, Bharat Institute of Higher Education and Research (BIHER), IN
1 Bharathiyar University, Coimbatore, IN
2 Department of Biochemistry, Sree Balaji Dental College and Hospital, Pallikaranai, Bharat Institute of Higher Education and Research (BIHER), IN
Source
Research Journal of Pharmacy and Technology, Vol 12, No 3 (2019), Pagination: 1265-1267Abstract
The aim of this study focused on the beneficial effect of EGCG which possess direct antioxidant potential in scavenging the free radicals. Therefore, EGCG was considered as one of the natural antioxidant in improving the quality of life by preventing cardiovascular diseases.Keywords
Antioxidant, Free Radicals, Cardiovascular Disease, Scavenging, EGCG-Epigallocatechin Gallate, 2,2 Diphenyl-1-Picrylhydrazyl (DPPH), Ferric Reducing Antioxidant Power (FRAP).References
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- Antihyperglycemic, Antidyslipidemic and Antifibrotic effect of EGCG in STZ - High Fat Diet Induced DCM Rats
Abstract Views :215 |
PDF Views:0
Authors
K. Pramila
1,
A. Julius
2
Affiliations
1 Bharathiyar University, Coimbatore. Sree Balaji Dental College and Hospital, Bharat Institute of Higher Education and Research (BIHER), Pallikaranai, Chennai – 600100., IN
2 Department of Biochemistry, Sree Balaji Dental College and Hospital, Bharat Institute of Higher Education and Research (BIHER), Pallikaranai, Chennai – 600100., IN
1 Bharathiyar University, Coimbatore. Sree Balaji Dental College and Hospital, Bharat Institute of Higher Education and Research (BIHER), Pallikaranai, Chennai – 600100., IN
2 Department of Biochemistry, Sree Balaji Dental College and Hospital, Bharat Institute of Higher Education and Research (BIHER), Pallikaranai, Chennai – 600100., IN
Source
Research Journal of Pharmacy and Technology, Vol 12, No 4 (2019), Pagination: 1839-1842Abstract
This study shows the potential effect of EGCG in DCM induced rats by exerting anti- hyperglycemic, anti-hyperlipidemic and anti-fibrotic effects. Hence EGCG a natural occurring compound have important clinical implications in terms of prevention and progression of diabetic cardiomyopathy.Keywords
DCM– Diabetic Cardiomyopathy, Anti-Hyperglycemic, Anti-Hyperlipidemic, Anti-Fibrotic, EGCG- Epigallocatechin Gallate.References
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