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Authors
Affiliations
1 Department of Microbiology, School of Bioengineering and Biosciences, Lovely Professional University, Phagwara, 144402, Punjab, IN
Source
Research Journal of Pharmacy and Technology, Vol 10, No 2 (2017), Pagination: 575-578
Abstract
Urinary tract infection (UTI) is a very common and prevalent type of bacterial infection in females, therefore current study was designed to investigate the prevalence of microorganisms in female UTIs cases and their resistance patterns. During the study, a total of 281 urine samples were collected from females clinically suspected for urinary tract Infections (UTIs) and processed for the isolation and characterization of bacteria by classical cultural methods. Following this, these isolates were subjected to antimicrobial susceptibility testing by agar disk diffusion method to study their drug resistance patterns. Among 58 microbes isolated from the patients, Escherichia coli (58.62%) was the most prevalent etiological agent followed by Klebsiella sp. (8.62%), Staphylococcus aureus (5.17%), Enterococcus sp. (3.44%) and Enterobacter sp. (3.44%), while Candida albicans was also highly prevalent with 20.68% of UTI cases. Antimicrobial susceptibility analysis of uropathogens exhibited maximum resistant towards nalidixic acid while minimum against netillin (8.69%). Based on the results it can be concluded that E. coli is one of the most prevalent etiological agent of UTIs and a large number of uropathogens exhibits resistant towards multiple antibiotics, therefore its extremely important to know the sensitivity data for UTIs to initiate an effective empirical therapy.
Keywords
Antibiotic Resistance, Urinary Tract Infection, Escherichia coli, Uropathogens, Empirical Therapy.
