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A.N, Luferov
- Apium Graveolens L.: A Phytochemical and Pharmacological Review
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Authors
Makarova E.I.
1,
Bokov D.O.
1,
Sergunova E.V.
1,
Chevidaev V.V.
1,
Kakhramanova S.D
1,
Bessonov V.V
2,
Friesen N.V
1,
Luferov A.N
1
Affiliations
1 Sechenov First Moscow State Medical University, 8 Trubetskaya St., Bldg. 2, Moscow, 119991, RU
2 Federal Research Center of Nutrition, Biotechnology and Food Safety, 2/14 Ustyinsky pr., Moscow, 109240, RU
1 Sechenov First Moscow State Medical University, 8 Trubetskaya St., Bldg. 2, Moscow, 119991, RU
2 Federal Research Center of Nutrition, Biotechnology and Food Safety, 2/14 Ustyinsky pr., Moscow, 109240, RU
Source
Research Journal of Pharmacy and Technology, Vol 15, No 2 (2022), Pagination: 927-934Abstract
Phytochemical composition data of various parts of celery (Apium graveolens L.) and pharmacological activity thereof are analyzed herein. Flavonoids, organic acids, hydroxycinnamic acids, ether oil terpenoids, tannins, vitamins and microelements are A. graveolens biologically active substances (BAS). Rich composition of BAS causes multiple both biological and pharmacological effects of herbal raw materials extracts mainly due to antioxidant activity. Furthermore, the extracts have neuroprotective, anti-inflammatory, hypolipidemic, antihypertensive and antibacterial effects. A. graveolens possesses wide spectrum of pharmacological activities and is a nontoxic plant; A. graveolens-based medicines will have high margin of safety. The results obtained provide opportunities for making herbal pharmaceutical celery-based substances and introduction thereof into the academic medicine.Keywords
Celery, Apium graveolens, Extracts, Phytochemical Composition, Biologically Active Substances.
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