ScieXplore: International Journal of Research in Science

Open Access Open Access  Restricted Access Subscription Access

Antimicrobial Activity of Leucas aspera (Willd.) Link on Selected Bacterial and Fungal Species


Affiliations
1 Post Graduate and Research Department of Zoology, Sri Vasavi College, Erode - 638316, Tamil Nadu,, India
2 Post Graduate and Research Department of Zoology, Sri Vasavi College, Erode - 638316, Tamil Nadu, India
 

Leucas aspera is a short green and highly branched herb that belongs to the family Labiatae and order tubiflorae. The present study indented to explore the pharmacological potential of the selected plant species Leucas aspera through antimicrobial studies and phytochemical studies. Leucas aspera plants for the present study are collected from farms of Guruvarediyur Village, Erode District. Extraction of the plant materials is followed by standard methods. The plant extract was tested for antibacterial and antifungal activity by the standard agar well-diffusion method. The antibacterial and antifungal activity of L. aspera extracts also supported the results of some previous studies and the study strongly proves the potential antimicrobial activity of the plant.

Keywords

Antibacterial and Antifungal Activity, Leucas aspera, Pharmacological Potential
User
Notifications
Font Size


  • Kaci Z, Tirchi N, Dahmane T, Berrai H, Sihem RH, Boubekeur, Chebli A, Biche M. First ethnobotanical study relating to usage of medicinal plants in province of Ain Defla Region, South-West of Algeria. Indian Journal of Ecology. 2022; 49(3):655-664. https://doi.org/10.55362/IJE/2022/3576

  • Chessbrough M. Medical laboratory manual for tropical countries. Linacre House, Jordan Hill. Oxford; 2000. p. 260.

  • Harborne JB. Phytochemical methods. Chapman and Hill; 1973.

  • Kokate CK. Practical pharmacognosy. 4th ed. Vallabh Prakasan, Delhi; 1994. p. 107 - 113.

  • Sani AA, Ilyas M, Haruna AK. Phytochemical screening of the leaves of lophiralanceolata (Ochanaceae). Life Science Journal. 2007; 4(4):75-79.

  • Karthikeyan S, Sivakumar A, Anbalagan M, Nalini E, Gothandam KM. Finger printing of alkaloids, steroids and flavonoids using HPTLC of Leucas aspera L. whole plant Methanolic extract. J Pharm Sci and Res. 2013; 5:67-71.

  • Ilango K, Ramya S, Gopinath G. Antibacterial activity of Leucas aspera spreng. Int J Chem Sci. 2008; 6(2): 526-530.

  • Saritha K, Rajesh A, Manjulatha K, Setty OH, Yenugu S. Mechanism of antibacterial action of the alcoholic extracts of Hemidesmus indicus (L.) R. Br. ex Schult, Leucas aspera (Wild.), Plumbago zeylanica L., and Tridax procumbens (L.) R. Br. ex Schult. Front Microbiol. 2015; 6:577. https://doi.org/10.3389/fmicb.2015.00577 PMid:26106379 PMCid:PMC4460426

  • Rahman MA, Islam MS. Antioxidant, antibacterial and cytotoxic effects of the phytochemicals of whole Leucas aspera extract. Asian Pac J Trop Biomed. 2013; 3:273- 279. https://doi.org/10.1016/S2221-1691(13)60062-3. PMid:23620850

  • Udayakumar R, Begum VH. Antimicrobial studies of some selected medicinal plants. Anc Sci Life. 2002; 21:230-239.

  • Rajakaruna N, Harris CS, Towers GHN. Antimicrobial activity of plants collected from serpentine outcrops in Sri Lanka. Pharm Biol. 2002; 40:235-244. https://doi. org/10.1076/phbi.40.3.235.5825

  • Valsaraj R, Pushpagadan P, Smitt UW, Adsersen A, Nyman U. Antimicrobial screening of selected medicinal plants from India. J Ethnopharmacol. 1997; 58:75- 83. https://doi.org/10.1016/S0378-8741(97)00085-8 PMID:9406894

  • Mangathayaru K, Thirumurugan D, Patel PS, Pratap DV, David DJ, Karthikeyan J. Isolation and identification of nicotine from Leucas aspera (willd) Indian J Pharm Sci. 2006; 68:88-90. https://doi.org/10.4103/0250- 474X.22972

  • Perez C, Paul M, Bazerque P. Antibiotic assay by agar well diffusion methods. Acta Boil Med Exp. 1990; 15:113-115

  • Sayedalam M, Sanjit S, Lee DU. Antibacterial and In vivo cytotoxic activities of the leaves of Leucas aspera. J Korean Soc Appl Biol Chem. 2014; 57(2014):551-554. https://doi.org/10.1007/s13765-014-4202-1

  • Thakur DK, Misra SK, Choudhuri PC. In vitro trials of plants extracts and chemicals for their antifungal activity. Indian J Animal Health. 1987; 26:31-35.

  • Akther M, Khan MAI, Mushin MDA, Hamid K, Obayed Ullah M., Bulbul IJ, Firoz A., Burkan Uddin M, Urmi KF. Invitro studies on antifungal and cytogenic properties of Leucas aspera. B. Mid., 2012; 4:183-187.


Abstract Views: 402

PDF Views: 180




  • Antimicrobial Activity of Leucas aspera (Willd.) Link on Selected Bacterial and Fungal Species

Abstract Views: 402  |  PDF Views: 180

Authors

M. Saravanaraja
Post Graduate and Research Department of Zoology, Sri Vasavi College, Erode - 638316, Tamil Nadu,, India
P. S. Arunadevi
Post Graduate and Research Department of Zoology, Sri Vasavi College, Erode - 638316, Tamil Nadu, India
M. Aamina
Post Graduate and Research Department of Zoology, Sri Vasavi College, Erode - 638316, Tamil Nadu, India

Abstract


Leucas aspera is a short green and highly branched herb that belongs to the family Labiatae and order tubiflorae. The present study indented to explore the pharmacological potential of the selected plant species Leucas aspera through antimicrobial studies and phytochemical studies. Leucas aspera plants for the present study are collected from farms of Guruvarediyur Village, Erode District. Extraction of the plant materials is followed by standard methods. The plant extract was tested for antibacterial and antifungal activity by the standard agar well-diffusion method. The antibacterial and antifungal activity of L. aspera extracts also supported the results of some previous studies and the study strongly proves the potential antimicrobial activity of the plant.

Keywords


Antibacterial and Antifungal Activity, Leucas aspera, Pharmacological Potential

References





DOI: https://doi.org/10.15613/sijrs%2F2021%2Fv8i1-2%2F217892