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Fluoxetine-Induced Recurrent Hypoglycemia


Affiliations
1 IQRAA International Hospital and Research Centre, Calicut - 673009, Kerala, India
     

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Selective Serotonin Reuptake Inhibitors (SSRIs) are known to affect glucose metabolism and can cause hypoglycaemia in diabetic patients. There are two reports of SSRI-induced hypoglycaemia in non diabetic elderly females. We report fluoxetine induced recurrent hypoglycaemia in a non diabetic middle aged female with obsessive compulsive disorder, which has hitherto not been reported.

Keywords

Adverse Drug Reactions, Fluoxetine, Hypoglycaemia.
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  • Goodnick PJ, Henry JH, Buki VM. Treatment of depression in patients with diabetes mellitus. J Clin Psychiatry. 1995; 56:128–36.
  • Deeg MA, Lipkin EW. Hypoglycemia associated with the use of fluoxetine. West J Med. 1996; 164:262–3.
  • Takhar J, Williamson P. Hypoglycemia associated with high doses of sertraline and sulphonylurea compound in a noninsulin-dependent diabetes mellitus patient. Can J Clin Pharmacol. 1999; 6:12–4.
  • Derijks HJ, Meyboom RH, Heerdink ER, De Koning FH, Janknegt R, Lindquist M, et al. The association between antidepressant use and disturbances in glucose homeostasis: Evidence from spontaneous reports. Eur J Clin Pharmacol. 2008; 64:531–8.
  • Pollak PT, Mukherjee SD, Fraser AD. Sertraline-induced hypoglycemia. Ann Pharmacother. 2001; 35:1371–4.
  • Zammit P. SSRI-induced hypoglycaemia causing confusion in nondiabetic octogenarian. Ann Long-Term Care Clin Care Aging. 2012; 20:28–30.
  • Naranjo CA, Busto U, Sellers EM, Sandor P, Ruiz I, Roberts EA, et al. A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther. 1981; 30:239–45.
  • Yamada J, Sugimoto Y, Inoue K. Selective serotonin reuptake inhibitors fluoxetine and fluvoxamine induce hyperglycemia by different mechanisms. Eur J Pharmacol. 1999; 382:211–5.
  • Araya V, Contreras P, Aguirre C, Depix MS, Zura ML. The effect of fluoxetine on insulin resistance in non diabetic obese patients. Rev Med Chil. 1995; 123:943–7.

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  • Fluoxetine-Induced Recurrent Hypoglycemia

Abstract Views: 594  |  PDF Views: 14

Authors

N. A. Uvais
IQRAA International Hospital and Research Centre, Calicut - 673009, Kerala, India

Abstract


Selective Serotonin Reuptake Inhibitors (SSRIs) are known to affect glucose metabolism and can cause hypoglycaemia in diabetic patients. There are two reports of SSRI-induced hypoglycaemia in non diabetic elderly females. We report fluoxetine induced recurrent hypoglycaemia in a non diabetic middle aged female with obsessive compulsive disorder, which has hitherto not been reported.

Keywords


Adverse Drug Reactions, Fluoxetine, Hypoglycaemia.

References





DOI: https://doi.org/10.22506/ti%2F2015%2Fv22%2Fi3%2F137640