Toxicology International (Formerly Indian Journal of Toxicology)

Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

Pattern of Acute Adult Poisoning in Gorgan, North of Iran


Affiliations
1 Pharmaceutical Sciences Research Center, Department of Pharmacology and Toxicology, Mazandaran University of Medical Sciences, Sari, Iran, Islamic Republic of
2 Dept. of Biostatistics and Epidemiology, School of Public Health, Hamadan University of Medical Science, Hamadan, Iran, Islamic Republic of
3 Department of Surgery, Golestan University of Medical Science, Gorgan, Iran, Islamic Republic of
4 Mazandaran University of Medical Sciences, Sari, Iran, Islamic Republic of
5 Azar Hospital, Golestan University of Medical Science, Gorgan, Iran, Islamic Republic of
6 Islamic Azad University, Shahrood Branch, Shahrood, Iran, Islamic Republic of
7 Golestan University of Medical Sciences, Gorgan, Iran, Islamic Republic of
8 Islamic Azad University, Sari Branch, Sari, Iran, Islamic Republic of
9 Health Management and Social Development Research Center, Golestan University of Medical Sciences, Gorgan, Iran, Islamic Republic of
     

   Subscribe/Renew Journal


Acute poisoning is a serious global problem. The aim of this study was to identify the trends and characteristics of acute poisoning in Gorgan, North of Iran. The study was carried out retrospectively on acute adult poisoning cases who were hospitalized in 5th Azar Hospital of Gorgan, from March 2008 to March 2015. Data were obtained from patient records in a preset checklist. Stata software (version 11) was used for data analysis. Of 800 patients, 55.88% were men and 44% were aged 20-29 years. The majority of patients (75.38%) lived in urban areas. Poisoning occurred mostly in summer and the peak was observed in Aug. Most of the poisoning agents were pharmaceuticals (71.62%). Among the pharmaceutical agents, benzodiazepines were involved most often. Overall, 38 patients (4.75%) died. The highest number of deaths was due to aluminum phosphide poisoning (42.10%). Intentional poisoning were identified as the main kind of poisoning, In addition, family quarrel was the main cause of intentional poisoning (31.60%).There were significant differences between poisoning and demographics characteristics including gender (P=0.001), age group (P<0.001), marital status (P<0.001), employment status (P<0.001) and educational status (P<0.001). Intentional poisoning by pharmaceutical agents were identified as the main cause of poisoning. Finally, people with these characteristics should be targeted prevention and educational programs against intentional poisoning.

Keywords

Intention, Suicide, Poisoning, Adult, Iran.
User
Subscription Login to verify subscription
Notifications
Font Size

  • Islambulchilar M, Islambulchilar Z, Kargar-Maher M. Acute adult poisoning cases admitted to a university hospital in Tabriz, Iran. Human & experimental toxicology. 2009;28(4):185-90.

  • Tsalkidis A, Vaos G, Gardikis S, Kambouri K, Tripsianis G, Mantadakis E, et al. Acute poisoning among children admitted to a regional university hospital in Northern Greece. Central European journal of public health. 2010;18(4):219.

  • Singh B, Unnikrishnan B. A profile of acute poisoning at Mangalore (South India). Journal of clinical forensic medicine. 2006;13(3):112-6.

  • Singh SP, Aggarwal AD, Oberoi SS, Aggarwal KK, Thind AS, Bhullar DS, et al. Study of poisoning trends in north India–a perspective in relation to world statistics. Journal of forensic and legal medicine. 2013;20(1):14-8.

  • Lund C, Teige B, Drottning P, Stiksrud B, Rui TO, Lyngra M, et al. A one-year observational study of all hospitalized and fatal acute poisonings in Oslo: epidemiology, intention and follow-up. BMC public health. 2012;12(1):858.

  • Sawalha AF, Sweileh WM, Tufaha MT, Al‐Jabi DY. Analysis of the pattern of acute poisoning in patients admitted to a governmental hospital in Palestine. Basic & clinical pharmacology & toxicology. 2010;107(5):914-8.

  • Randev S, Grover N, Sharma R, Sharma H. Acute poisoning in children: seven year experience at a tertiary care hospital of north India. Current Pediatric Research. 2011;15(1).

  • Hovda KE, Bjornaas M, Skog K, Opdahl A, Drottning P, Ekeberg O, et al. Acute poisonings treated in hospitals in Oslo: a one-year prospective study (I): pattern of poisoning. Clinical toxicology. 2008;46(1):35-41.

  • Karbakhsh M, Zandi NS. Pattern of poisoning in the elderly: an experience from Tehran. Clinical toxicology. 2008;46(3):211-7.

  • Akhlaghi M, Arbabi Z, Khadivi R. Pattern of acute poisoning in Shahrekord (Western Iran). Asian Journal of Epidemiology. 2009;2(1):9-12.

  • Tufekci IB, Curgunlu A, Şirin F. Characteristics of acute adult poisoning cases admitted to a university hospital in Istanbul. Human & experimental toxicology. 2004;23(7):347-51.

  • Malangu N. Acute poisoning at two hospitals in Kampala– Uganda. Journal of forensic and legal medicine. 2008;15(8):489-92.

  • Patil A, Peddawad R, Verma VCS, Gandhi H. Profile of Acute Poisoning Cases Treated in a Tertiary Care Hospital: a Study in Navi Mumbai. Asia Pacific Journal of Medical Toxicology. 2014;3(1):36-40.

  • Zhang J, Jia S, Wieczorek WF, Jiang C. An overview of suicide research in China. Archives of Suicide Research. 2002;6(2):167-84.

  • Balai‐Mood M. Pattern of acute poisonings in Mashhad, Iran 1993–2000. Journal of Toxicology: Clinical Toxicology. 2004;42(7):965-75.

  • Moghadamnia A, Abdollahi M. An epidemiological study of poisoning in northern Islamic Republic of Iran. 2002.

  • Khlifi M, Zun L, Johnson G, Harbison R. Etiological characterization of acute poisonings in the emergency department. Journal of Emergencies, Trauma and Shock. 2009;2(3):159.

  • Ramesha K, Rao KB, Kumar GS. Pattern and outcome of acute poisoning cases in a tertiary care hospital in Karnataka, India. Indian journal of critical care medicine: peer-reviewed, official publication of Indian Society of Critical Care Medicine. 2009;13(3):152.

  • Dash SK, Raju AS, Mohanty MK, Patnaik KK, Mohanty S. Sociodemographic profile of poisoning cases. 2005.

  • Dhattarwal S, Singh H. Profile of deaths due to poisoning in Rohtak, Haryana. Journal of forensic medicine and toxicology. 2001;18(2):28-9.

  • Kanchan T, Menezes RG, Kumar TM, Bakkannavar SM, Bukelo MJ, Sharma PS, et al. Toxicoepidemiology of fatal poisonings in Southern India. Journal of forensic and legal medicine. 2010;17(6):344-7.

  • Mert E, Bilgin NG. Demographical, aetiological and clinical characteristics of poisonings in Mersin, Turkey. Human & experimental toxicology. 2006;25(4):217-23.

  • Shadnia S, Esmaily H, Sasanian G, Pajoumand A, HassanianMoghaddam H, Abdollahi M. Pattern of acute poisoning in Tehran-Iran in 2003. Human & experimental toxicology. 2007;26(9):753-6.

  • Sobhani A, Shojaii-Tehrani H, Nikpour E, NOROUZI RN. Drug and chemical poisoning in northern Iran. 2000.

  • Burillo-Putze G, Munne P, Duenas A, Pinillos MA, Naveiro JM, Cobo J, et al. National multicentre study of acute intoxication in emergency departments of Spain. European Journal of Emergency Medicine. 2003;10(2):101-4.

  • Guloglu C, Kara IH. Acute poisoning cases admitted to a university hospital emergency department in Diyarbakir, Turkey. Human & experimental toxicology. 2005;24(2):49-54.

  • PRKA I, VUJANI S, Dabo N, PAL I, NAUMOVSKI-MIHALI S. Cases of acute poisoning admitted to Clinical Hospital Merkur in Zagreb in 1999. Arh Hig Rada Toksikol. 2001;52:315-21.

  • Lau F. Emergency management of poisoning in Hong Kong. Hong Kong Medical Journal. 2000;6(3):288-92.

  • Ghaznawi HI, Gamal-Eldin H, Khalil AM. Poisoning problem in Jeddah region. Ann Saudi Med. 1998;18(5):460-2.

  • Liu Y, Wolf LR, Zhu W. Epidemiology of adult poisoning at China Medical University. Journal of Toxicology: Clinical Toxicology. 1997;35(2):175-80.

  • Carlsten A, Waern M, Allebeck P. Suicides by drug poisoning among the elderly in Sweden 1969–1996. Social psychiatry and psychiatric epidemiology. 1999;34(11):609-14.

  • Abdollahi M, Jalali N, Sabzevari O, Hoseini R, Ghanea T. A Restrospective Study of Poisoning in Tehran. Clinical Toxicology. 1997;35(4):387-93.

  • Vatandoost H, Mirakbari S. Study Of Poisoning In Adults At Poison Control Center, Loqman-E Hakeem Hospital Tehran-Iran From April 25, 2000 To April 25 2001. The Internet Journal of Pharmacology. 2002;1(2).

  • Apellániz A, Manzanaro R. Characteristics of the poisoning mortality in the 1986-2001 period in the Autonomous Basque Community, Spain. Revista Española de Salud Pública. 2005;79(5):569-79.

  • Presgrave RdF, Camacho LAB, Villas Boas MHS. A profile of unintentional poisoning caused by household cleaning products, disinfectants and pesticides. Cadernos de Saúde Pública. 2008;24(12):2901-8.


Abstract Views: 679

PDF Views: 1




  • Pattern of Acute Adult Poisoning in Gorgan, North of Iran

Abstract Views: 679  |  PDF Views: 1

Authors

Mohammad Shokrzadeh
Pharmaceutical Sciences Research Center, Department of Pharmacology and Toxicology, Mazandaran University of Medical Sciences, Sari, Iran, Islamic Republic of
Reza Hoseinpoor
Dept. of Biostatistics and Epidemiology, School of Public Health, Hamadan University of Medical Science, Hamadan, Iran, Islamic Republic of
Amir Hajimohammadi
Department of Surgery, Golestan University of Medical Science, Gorgan, Iran, Islamic Republic of
Mahdi Rezaei
Mazandaran University of Medical Sciences, Sari, Iran, Islamic Republic of
Azam Delaram
Azar Hospital, Golestan University of Medical Science, Gorgan, Iran, Islamic Republic of
Mona Pahlavani
Islamic Azad University, Shahrood Branch, Shahrood, Iran, Islamic Republic of
Motahare Esmaily
Golestan University of Medical Sciences, Gorgan, Iran, Islamic Republic of
Gholamali Lashkarboloki
Islamic Azad University, Sari Branch, Sari, Iran, Islamic Republic of
Yaghoub Shayeste
Health Management and Social Development Research Center, Golestan University of Medical Sciences, Gorgan, Iran, Islamic Republic of

Abstract


Acute poisoning is a serious global problem. The aim of this study was to identify the trends and characteristics of acute poisoning in Gorgan, North of Iran. The study was carried out retrospectively on acute adult poisoning cases who were hospitalized in 5th Azar Hospital of Gorgan, from March 2008 to March 2015. Data were obtained from patient records in a preset checklist. Stata software (version 11) was used for data analysis. Of 800 patients, 55.88% were men and 44% were aged 20-29 years. The majority of patients (75.38%) lived in urban areas. Poisoning occurred mostly in summer and the peak was observed in Aug. Most of the poisoning agents were pharmaceuticals (71.62%). Among the pharmaceutical agents, benzodiazepines were involved most often. Overall, 38 patients (4.75%) died. The highest number of deaths was due to aluminum phosphide poisoning (42.10%). Intentional poisoning were identified as the main kind of poisoning, In addition, family quarrel was the main cause of intentional poisoning (31.60%).There were significant differences between poisoning and demographics characteristics including gender (P=0.001), age group (P<0.001), marital status (P<0.001), employment status (P<0.001) and educational status (P<0.001). Intentional poisoning by pharmaceutical agents were identified as the main cause of poisoning. Finally, people with these characteristics should be targeted prevention and educational programs against intentional poisoning.

Keywords


Intention, Suicide, Poisoning, Adult, Iran.

References





DOI: https://doi.org/10.22506/ti%2F2016%2Fv23%2Fi2%2F146689