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Therapeutic Management of Toxicity of Ficus tsjahela Leaves in Cattle
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The toxicity episodes of Ficus tsjahela leaves cattle and treatment regimen were studied. The clinical signs in Ficus tsjahela toxicity were salivation, generalized clonic and tonic seizures, nystagmus, stereotypic gnawing behavior, hyperesthesia, ataxia, paddling movements while in recumbency and stereotyped gnawing behavior or eating inanimate objects. The affected animals were treated effectively with diazepam @ 0.5 mg/kg i/v and thiamine hydrochloride @ 10 mg/kg i/m with intravenous administration of 5-10 ml/kg of 10 % dextrose solution twice at 10 to 12 h interval for 3-4 days till complete recovery. There was no change in serum concentrations of ALT, AST, BUN, creatinine, calcium, magnesium, phosphorus except acute hyperglycemia. The phytochemical analysis revealed the presence of steroids, terpenes, diterpenes, lactones, flavonoids, tannins and glycosides. The results of this study demonstrated the toxicity of Ficus tsjahela leaves in cattle and its therapeutic management with diazepam, thiamine hydrochloride and dextrose.
Keywords
Ficus tsjahela, Toxicity, Cattle, Treatment, Diazepam, Thiamine, Dextrose.
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- Shridhar, N.B., Toxicity of Ficus tsjahela leaves in cattle and its treatment http://www.ivis.org/proceedings/wbc/2010/AbstractCD/OP-PO02q.htm
- Shridhar, N. B., Krishna, N. S. and Santhosh Kumar, C. N. Toxicity of Ficus Tsjahela leaves in cattle and its clinical management. Indian Vet.J., 2014;91(7) 49-50.
- Yoganarasimhan, S.N., Subramanium, K. and Razi, B.A. Flora of Chikkamagalur District. Karnataka, India, International Book Distributors, Dehradun, 1981; 308-309.
- Narayana, K., Pradeep, S.K., Usha, N. and Shridhar, N.B. (2003) Moraceae, In: Poisonous and Medical Plants. 1st ed. Jayashree Publications, Bangalore, pp. 17-18.
- Chanda, S.K. and Bhaid, M.U. Studies on the digestibility and nutritive value of common dried fodder tree leaves of M.P. on goats: 4. Hay of phephar tree leaves (Ficus tsiela Roxb). Livest. Advis.,1987;12, 5-8.
- Nair, N.D., Abraham, M.J., Valsala, K.V., Nair, M.G. and Rajan, A. Clinico-patho logical features of experimental chela leaf poisoning in calves. Kerala J. Vet. Sci., 1987;18, 84-90.
- Rajan, A., Nair, N.D., Valsala, K.V., Maryamma, K.I. and Ramachandran, K.M. Pathology of a nervous disorder in cattle caused by the toxicity of leaves of the tree Ficus tsiela Roxb. Indian Vet. J.,1986; 63,184-186.
- Rodostists, O.M., Blood, D.C. and Gay, C.C. Diseases of nervous System. In: Veterinary Medicine. 8th ed. E.L.B.S, London, 1994; 458-503.
- Riss, J., Cloyd, J., Gates, J. and Collins, S. Benzodiazepines in epilepsy: Pharmacology and pharmacokinetics. Acta Neurologica Scandinavica, 2008; 118 (2)69–86.
- Booth, N.H. and McDonald, L.E. Psychotropic agents. In: Veterinary Pharmacology and Therapeutics, 6th ed. Panima Publishing Corporation, New Delhi, 1998; 363-395.
- Krishna, N.S. Toxicity studies of Ficus tsjhela in cattle. M.V.Sc. Thesis submitted to University of Agricultural Sciences, Bengaluru, 1999.
- Bettendorff, L., Mastrogiacomo, F., Kish, S. J. and Grisar, T. Thiamine, thiamine phosphates and their metabolizing enzymes in human brain. J. Neurochem., 1996; 66 (1) 250–258.
- Tolga, K., Murat, D. and Omer, K. Thiamine status of feed-lot cattle fed a high-concentrate diet. Can. Vet. J., 2010; 51(11): 1251–1253.
- Ratnasooriya, W.D., Premakumar, G.A.S. and Tillekeratne, L.M.V. Exploratory behaviour of male rats treated with a crude extract of Ficus tsiela leaves. Med. Sci. Res.,1992; 20, 233-234.
- Geetha, B.S., Mathew, B.C. and Augusti, K.T. (1994). Hypoglycemic effects of leucodelphinidin derivative isolated from Ficus bengalensis (Linn). Indian J. Physiol. Pharmacol., 1994; 38, 220-222.
- Bafor, E.E and Igbinuwen, O. Acute toxicity studies of the leaf extract of Ficus exasperata on haematological parameters, body weight and body temperature. J. Ethnopharmacol., 2009; 123(2):302-307.
- Litty Mathew, Divakaran Nair, N., Vijayan, N. and Mercey, K. A. Hemato-biochemical and oxidative effect of fresh juice and ethanolic extract of Ficus tsiela Roxb in rats. Vet. World, 2014; 7(10) 890-894.
- Nair, N.D., Rajan, A. and Nair, M.K. Histopathology of toxicity of Ficus tsiela in cattle (1995) Indian J. Vet. Pathol., 19: 1-5.
- Myburgh, J.G., Fourie, N. Van der Lugt, J.J., Kellerman, T.S., Cornelius S, T., Ward, C. A nervous disorder in cattle, caused by the plants Ficus ingens var. ingens and Ficus cordata subsp. salicifolia. Onderstepoort J. Vet. Res., 1994; 61(2)171-6.
- Ramesh K. Satdive, Raghuram Chimata, Ajay Namdeo and Devanand, P. Fulzele. In vitro screening for phytochemical and antimicrobial activity of poisonous plant Ficus Tseila Roxb. Int. J. Pharma Bio. Sci., 2012; 3(2) 213-221.
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