Toxicology International (Formerly Indian Journal of Toxicology)

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Dose‑Dependent Olanzapine‑Induced Myoclonus


Affiliations
  • K. S. Mani Center for Cognitive Neurosciences, Departments of Psychiatry, Ranchi, India
  • Central Institute of Psychiatry, Psychiatry, Ranchi, India
     

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Second‑generation antipsychotics (SGA), mainly clozapine have been reported to induce myoclonus. Although olanzapine‑induced myoclonus is reported, dose‑dependent response has not been described. We report dose‑related olanzapine‑induced myoclonus in an early onset schizophrenia patient. We also suggest certain management strategies for such adverse side effects.

Keywords

Dose‑dependent, myoclonus, olanzapine
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  • Dose‑Dependent Olanzapine‑Induced Myoclonus

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Authors

Alok Pratap
, India

Abstract


Second‑generation antipsychotics (SGA), mainly clozapine have been reported to induce myoclonus. Although olanzapine‑induced myoclonus is reported, dose‑dependent response has not been described. We report dose‑related olanzapine‑induced myoclonus in an early onset schizophrenia patient. We also suggest certain management strategies for such adverse side effects.

Keywords


Dose‑dependent, myoclonus, olanzapine