Toxicology International (Formerly Indian Journal of Toxicology)

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Effect of Ethanol on Branchial Adenosine Triphosphatases in Oreochromis mossambicus (Peters)


Affiliations
1 Department of Marine Biology, Microbiology and Biochemistry, School of Marine Sciences, Cochin University of Science and Technology, Fine Arts Avenue, Cochin - 682 016, Kerala, India
     

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The aim of this work was to determine the toxicity of ethanol in an aquatic system by means of bioassays with Oreochromis mossambicus (Peters) as a test organism. The study revealed changes in the gill ATPase activities. The results obtained indicated that ethanol brought about a decrease in the body weight, followed by significant inhibition on total ATPase, Na+/K+ ATPase, Ca2+ ATPase and Mg2+ ATPase activities. The studies also indicated that these can be employed as suitable biomarkers in ethanol related toxicity studies.

Keywords

Analysis of variance, branchial ATPases, gill, Oreochromis mossambicus
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  • Effect of Ethanol on Branchial Adenosine Triphosphatases in Oreochromis mossambicus (Peters)

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Authors

Smitha V. Bhanu
Department of Marine Biology, Microbiology and Biochemistry, School of Marine Sciences, Cochin University of Science and Technology, Fine Arts Avenue, Cochin - 682 016, Kerala, India
Babu Philip
Department of Marine Biology, Microbiology and Biochemistry, School of Marine Sciences, Cochin University of Science and Technology, Fine Arts Avenue, Cochin - 682 016, Kerala, India

Abstract


The aim of this work was to determine the toxicity of ethanol in an aquatic system by means of bioassays with Oreochromis mossambicus (Peters) as a test organism. The study revealed changes in the gill ATPase activities. The results obtained indicated that ethanol brought about a decrease in the body weight, followed by significant inhibition on total ATPase, Na+/K+ ATPase, Ca2+ ATPase and Mg2+ ATPase activities. The studies also indicated that these can be employed as suitable biomarkers in ethanol related toxicity studies.

Keywords


Analysis of variance, branchial ATPases, gill, Oreochromis mossambicus