Oxidative stress due to ochratoxin and T-2 toxin either alone or in combination and evaluation of protective role of Curcuma longa, Zingiber officinale, toxichek and activated charcoal

A study was conducted on poultry to evaluate the oxidative stress due to ochratoxin and T-2 either alone or in combination. Broiler chicks were fed OTA @2ppm,T-2 @ 1ppm, Zingiber officinale (rhizome shade dried and powdered @ 0.5%, Curcuma longa rhizome @ 0.5%, toxichek @ 0.1% and activated charcoal @ 0.4% in feed in combinations of 20 groups. The study revealed a significant (p<0.05) increase in the activities of glutathione peroxidase, glutathione reductase, catalase and TBARS in toxic groups (OTA, T-2 and OTA+T-2). Results of the present study suggest that OTA and T-2 either alone or in combination induce oxidative stress and supplementation of Curcuma longa, Zingiber officinale, toxichek and activated charcoal in order showed amelioration by stabilizing the antioxidant defenses.