Toxicology International (Formerly Indian Journal of Toxicology)

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Emergence of Zebrafish as a Biomarker for Pesticide Poisoning in Forensic Toxicology Research


Affiliations
1 Laboratory of Analytical and Molecular Toxicology (Forensic Chemistry and Toxicology Laboratory), Institute of Forensic Science, Gujarat Forensic Sciences University, Sector 09, Gandhinagar – 382007, Gujarat, India
     

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Forensic toxicology is the branch of forensic science which utilizes toxicology, pharmacology and analytical chemistry to help in legal investigations of suicidal, homicidal and accidental poisoning cases. Accidental poisoning cases related to occupational exposure of pesticides are also very common. Zebrafish is a versatile model organism that has been used as a model organism in different field of science, has various practical advantages over other vertebrate models. Present review summarizes the effects of pesticides and the use of adult zebrafish as a model organism in forensic toxicology research to understand the symptoms/effects and mechanism of pesticide poisoning.

Keywords

Forensic Science, Forensic Toxicology, Oxidative Stress, Pesticide Poisoning, Zebrafish.
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  • Emergence of Zebrafish as a Biomarker for Pesticide Poisoning in Forensic Toxicology Research

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Authors

Saurabh Shukla
Laboratory of Analytical and Molecular Toxicology (Forensic Chemistry and Toxicology Laboratory), Institute of Forensic Science, Gujarat Forensic Sciences University, Sector 09, Gandhinagar – 382007, Gujarat, India
Reena C. Jhamtani
Laboratory of Analytical and Molecular Toxicology (Forensic Chemistry and Toxicology Laboratory), Institute of Forensic Science, Gujarat Forensic Sciences University, Sector 09, Gandhinagar – 382007, Gujarat, India
Rakhi Agarwal
Laboratory of Analytical and Molecular Toxicology (Forensic Chemistry and Toxicology Laboratory), Institute of Forensic Science, Gujarat Forensic Sciences University, Sector 09, Gandhinagar – 382007, Gujarat, India

Abstract


Forensic toxicology is the branch of forensic science which utilizes toxicology, pharmacology and analytical chemistry to help in legal investigations of suicidal, homicidal and accidental poisoning cases. Accidental poisoning cases related to occupational exposure of pesticides are also very common. Zebrafish is a versatile model organism that has been used as a model organism in different field of science, has various practical advantages over other vertebrate models. Present review summarizes the effects of pesticides and the use of adult zebrafish as a model organism in forensic toxicology research to understand the symptoms/effects and mechanism of pesticide poisoning.

Keywords


Forensic Science, Forensic Toxicology, Oxidative Stress, Pesticide Poisoning, Zebrafish.

References





DOI: https://doi.org/10.18311/ti%2F2018%2F22803