Toxicology International (Formerly Indian Journal of Toxicology)

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Effect of Silver Nanoparticles on Antioxidant Enzymes of Zebrafish, Danio Rerio


Affiliations
1 P.G. and Research Department of Zoology, B.P. Arts, Science and Commerce College, Affiliated to KBC, North Maharashtra University, Jalgaon, Chalisgaon – 424101, Maharashtra,, India
     

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The objective of the present study was to know the effect of Silver nanoparticle on antioxidant enzymatic activities in selected tissues of the Zebrafish, Danio rerio. For the chronic toxicity study adult fish, Danio rerio were divided in to two groups. First group was experimental group in which fish were consecutively treated with a graded series of 0.3, 0.6, 0.9 mg/l an average 60 nm PVP coated AgNPs. Treatment was given for 21 days at the end of experimental period. Superoxide Dismutase (SOD), Catalase (CAT) and Glutathione Peroxidase (GPx) in gill, liver and muscle tissues were assayed. The levels of Catalase (CAT), was found to be decreased were as the Superoxide Dismutase (SOD) and Glutathione Peroxidase (GPx) were found to be increased significantly in gill, liver and muscle tissue of AgNPs treated fish.

Keywords

Antioxidant Enzymes, Danio rerio, Nanotoxicology, Silver Nanoparticles (AgNPs).
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  • Effect of Silver Nanoparticles on Antioxidant Enzymes of Zebrafish, Danio Rerio

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Authors

A. D. Shelke
P.G. and Research Department of Zoology, B.P. Arts, Science and Commerce College, Affiliated to KBC, North Maharashtra University, Jalgaon, Chalisgaon – 424101, Maharashtra,, India

Abstract


The objective of the present study was to know the effect of Silver nanoparticle on antioxidant enzymatic activities in selected tissues of the Zebrafish, Danio rerio. For the chronic toxicity study adult fish, Danio rerio were divided in to two groups. First group was experimental group in which fish were consecutively treated with a graded series of 0.3, 0.6, 0.9 mg/l an average 60 nm PVP coated AgNPs. Treatment was given for 21 days at the end of experimental period. Superoxide Dismutase (SOD), Catalase (CAT) and Glutathione Peroxidase (GPx) in gill, liver and muscle tissues were assayed. The levels of Catalase (CAT), was found to be decreased were as the Superoxide Dismutase (SOD) and Glutathione Peroxidase (GPx) were found to be increased significantly in gill, liver and muscle tissue of AgNPs treated fish.

Keywords


Antioxidant Enzymes, Danio rerio, Nanotoxicology, Silver Nanoparticles (AgNPs).

References





DOI: https://doi.org/10.18311/ti%2F2020%2Fv27i3%264%2F25048