Toxicology International (Formerly Indian Journal of Toxicology)

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An Incidence of Onion (Allium Cepa) Toxicity In Cattle and Buffaloes.


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1 Obscure Disease Research Center, Karnataka Veterinary Animal and Fisheries Sciences University, Bidar, Veterinary College Campus, Shivamogga – 577204, Karnataka,, India
     

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Toxicity was caused by the accidental ingestion of a large quantity onion (Allium cepa) by 6 cattle and 4 water buffalos. The animals exhibited the clinical signs of pale mucous membranes, lethargy, anorexia and voiding dark urine after 8-10 days of ingestion of onion. The post mortem showed the odor of onion and the rumen found several bits of onions. The kidneys were dark brown with urine. Microscopy demonstrated tubular degeneration and necrosis in the cytoplasm of renal tubular epithelial cells and tubular lumina with eosinophilic substance deposits. Hemorrhage and macrophages containing brown cytoplasmic pigment with centrilobular coagulative necrosis were found in liver. The ailing animals recovered with therapy with fluids, phosphorus, B-complex vitamins and vitamin C for five consecutive days.

Keywords

Biochemistry, Buffaloes, Cattle, Hematology, Onion, Toxicity, Treatment.
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  • An Incidence of Onion (Allium Cepa) Toxicity In Cattle and Buffaloes.

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Authors

N . B. Shridhar
Obscure Disease Research Center, Karnataka Veterinary Animal and Fisheries Sciences University, Bidar, Veterinary College Campus, Shivamogga – 577204, Karnataka,, India

Abstract


Toxicity was caused by the accidental ingestion of a large quantity onion (Allium cepa) by 6 cattle and 4 water buffalos. The animals exhibited the clinical signs of pale mucous membranes, lethargy, anorexia and voiding dark urine after 8-10 days of ingestion of onion. The post mortem showed the odor of onion and the rumen found several bits of onions. The kidneys were dark brown with urine. Microscopy demonstrated tubular degeneration and necrosis in the cytoplasm of renal tubular epithelial cells and tubular lumina with eosinophilic substance deposits. Hemorrhage and macrophages containing brown cytoplasmic pigment with centrilobular coagulative necrosis were found in liver. The ailing animals recovered with therapy with fluids, phosphorus, B-complex vitamins and vitamin C for five consecutive days.

Keywords


Biochemistry, Buffaloes, Cattle, Hematology, Onion, Toxicity, Treatment.

References





DOI: https://doi.org/10.18311/ti%2F2020%2Fv27i3%264%2F25250