Asian Journal of Pharmaceutical Research and Health Care

The PDF file you selected should load here if your Web browser has a PDF reader plug-in installed (for example, a recent version of Adobe Acrobat Reader).

If you would like more information about how to print, save, and work with PDFs, Highwire Press provides a helpful Frequently Asked Questions about PDFs.

Alternatively, you can download the PDF file directly to your computer, from where it can be opened using a PDF reader. To download the PDF, click the Download link above.

Fullscreen Fullscreen Off


A simple, accurate and precise HPTLC method has been develop ed and validated for the estimation of nevirapine from bulk drug and tablet formulations. The s eparation was achieved on TLC plates using appropriate solvent system. The spots so devel oped were densometrically scanned at 283 nm. The linearity of the method was found to be wit hin the concentration range of 2.50μg/ml to 62.50μ/ml. The validation parameters, tested in ac cordance with the requirements of ICH guidelines, prove the suitability of this me thod. The method was successfully applied for determination of drug in tablets, wherein no interference from tablet excipients was observed, indicating the specificity of the developed method. Thus the proposed method can be used successfully for routine analysis of nevirapine from capsule and tablet formulations.

Keywords

Nevirapine, HPTLC, Validation, Precise, Accurate.
User
Notifications
Font Size