Evaluation of Efficacy and Toxicity of Different Treatment Regimens in Plasmodium Falciparum Malaria

The efficacy and toxicity of four commonly used antimalarials was evaluated. The combinations evaluated were Artesunate and Doxycycline, Quinine and Doxycycline, Artesunate and Quinine, Artesunate and Mefloquine. The four combinations did not show any statistically significant difference in terms of days of defervescence, parasite clearance and hospital stay. All the four combinations were well tolerated.