Asian Journal of Pharmaceutical Research and Health Care

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Pro Oxidants and Antioxidants Levels in Chronic Renal Failure Patients Treated by Dialysis


Affiliations
1 Apollo Institute of Medical Sciences and Research, Department of Biochemistry, Hyderabad – 500033, Telangana, India
2 Department of Biochemistry, Kamineni Institute of Medical Sciences, Narketpally, Telangana, India
3 Apollo Institute of Medical Sciences and Research, Department of Pharmacology, Hyderabad – 500033, Telangana, India
 

To assess adjustments in star oxidant and cancer prevention agent state in pre and post hemodialysis patients experiencing ceaseless renal disease. The study was led on 100 perpetual renal disappointment patients going to outpatient division of nephrology dialysis unit in relationship with bureau of organic chemistry at Kamineni establishment of therapeutic Sciences, Narketpally, Nalgonda district, Telangana. Age between 30-70 years of either sex measuring their estimated oxidant levels of serum malondialdehyde, serum protein carbonyls and anti-oxidant levels of serum superoxide dismutase, serum catalase prior and then afterward the dialysis session coordinated controls. In the present study, we have observed significant increase in levels of pro-oxidants serum malondialdehyde and serum protein carbonyls fixation and there was reduction in chemical action of cell reinforcement serum superoxide dismutase and serum catalase. Our study highlights the need of screening of cancerous agents in renal Patients in regular intervals for better treatment outcomes and also to improve quality of life of the patients.

Keywords

Antioxidants, Chronic Kidney Disease, Dialysis, Pro Oxidants.
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  • Pro Oxidants and Antioxidants Levels in Chronic Renal Failure Patients Treated by Dialysis

Abstract Views: 468  |  PDF Views: 186

Authors

Neetha Kundoor
Apollo Institute of Medical Sciences and Research, Department of Biochemistry, Hyderabad – 500033, Telangana, India
Shruti Mohanty
Department of Biochemistry, Kamineni Institute of Medical Sciences, Narketpally, Telangana, India
Radha Kishan Narsini
Apollo Institute of Medical Sciences and Research, Department of Biochemistry, Hyderabad – 500033, Telangana, India
T. Naveen Kumar
Apollo Institute of Medical Sciences and Research, Department of Pharmacology, Hyderabad – 500033, Telangana, India

Abstract


To assess adjustments in star oxidant and cancer prevention agent state in pre and post hemodialysis patients experiencing ceaseless renal disease. The study was led on 100 perpetual renal disappointment patients going to outpatient division of nephrology dialysis unit in relationship with bureau of organic chemistry at Kamineni establishment of therapeutic Sciences, Narketpally, Nalgonda district, Telangana. Age between 30-70 years of either sex measuring their estimated oxidant levels of serum malondialdehyde, serum protein carbonyls and anti-oxidant levels of serum superoxide dismutase, serum catalase prior and then afterward the dialysis session coordinated controls. In the present study, we have observed significant increase in levels of pro-oxidants serum malondialdehyde and serum protein carbonyls fixation and there was reduction in chemical action of cell reinforcement serum superoxide dismutase and serum catalase. Our study highlights the need of screening of cancerous agents in renal Patients in regular intervals for better treatment outcomes and also to improve quality of life of the patients.

Keywords


Antioxidants, Chronic Kidney Disease, Dialysis, Pro Oxidants.

References





DOI: https://doi.org/10.18311/ajprhc%2F2017%2F14740