Asian Journal of Pharmaceutical Research and Health Care

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Leadership and Task Shifting to Address the Challenges of Antimicrobial Resistance in South Africa


Affiliations
1 Rhodes University, Grahamstown, South Africa
2 Ambulatory Pharmacy Services, Cleveland Clinic, Abu Dhabi, United Arab Emirates
3 Department of Pharmacy Practice, Visveswarapura Institute of Pharmaceutical Sciences, Bengaluru, India
4 Rhodes Business School, Rhodes University, Grahamstown, South Africa
5 YP-CDN, United States
6 Department of Anthropology, Rhodes University, Grahamstown, South Africa
7 College of Pharmacy, Jinan University, Guangzhou, China
 

Antimicrobial resistance is a complex problem interconnected with many factors, such as overuse and misuse of antimicrobials across the world, especially in Low- and Middle-Income Countries (LMICs). To overcome this, the Global Action Plan requires commitment action in LMICs, aimed at education and health promotion to all. Demand for the Health Care Professionals (HCPs) in developed countries and exponential chances of earning had led to the shortage of HCPs in most countries and severe shortage in more than 50 LMICs. Community Health Workers (CHWs) are being recognised in many LMICs to deliver primary health care service with minimum training as an alternative solution to combat the situation, which can improve the cost-effectiveness of health care systems. These CHWs can reach large number of people in the community where the public sector provided health service is very minimal and private health care sector is unaffordable.

Keywords

Antimicrobial Agents, Antimicrobial Resistance, Community Health Workers, Leadership, Task Shifting, World Health Organisation, Youth Empowerment.
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  • Global Union for Antibiotics Research and Development (GUARD). Berlin Declaration on Antimicrobial Resistance; 2015. Available from: crossref

  • Michael CA, Dominey-Howes D and Labbate M. The antimicrobial resistance crisis: Causes, consequences, and management. Front. Public Health. 2014; 2:145. crossref

  • Centers for Disease Control and Prevention, Office of Infectious Disease Antibiotic resistance threats in the United States; 2013. Available from: crossref

  • Report of the first meeting of the interagency coordination group on antimicrobial resistance. 2017 May. Available from: crossref

  • World Health Organisation. Implementation of the Global Action Plan on Antimicrobial Resistance. WHO GAP AMR Newsletter No. 26. 2017 May. Available from: crossref

  • Llor C, Bjerrum L. Antimicrobial resistance: risk associated with antibiotic overuse and initiatives to reduce the problem. Ther Adv Drug Saf. 2014; 5(6):229–41. crossref PMid:25436105 PMCid:PMC4232501

  • Richard JF, Tor Y. Antibiotics and bacterial resistance in the 21st century. Perspect Medicin Chem. 2014; 6:25–64.

  • Gibson PC, Govender N, Lewis D A, Bamford C, Brink A, Gottberg A von et al. Human infections and antibiotic resistance. The South African Medical Journal. 2011; 101(8):567–78.

  • Powers JH. Antimicrobial drug development- the past, the present, and the future. Clin Microbiol Infect. 2004; 10(s4):23–31. crossref PMid:15522037

  • World Health Organisation. Noncommunicable diseases. WHO, Geneva; 2017. Available from: crossref

  • Roger SM, Patterson D. The role of law and governance reform in the global response to non-communicable diseases. Magnusson and Patterson Globalization and Health. 2014; 10:44. crossref PMid:24903332 PMCid:PMC4077679

  • World Health Organisation. Global action plan on antimicrobial resistance. WHO, Geneva, 2015 Sep; Available from: crossref

  • Organisation for economic co-operation and development. Antimicrobial resistance: Policy insight. OECD, France; 2016. Available from: crossref

  • Outterson K, Powers JH, Daniel GW, McClellan MB. Repairing the broken market for antibiotic innovation. Health Affairs. 2015; 34(2):277–85. crossref PMid:25646108

  • Review on antimicrobial resistance. Tackling Drug-Resistant Infections Globally: Final report and Recommendations. 2016 May. Available from: crossref

  • Chantal MM, Elias M. Stoking the antibiotic pipeline. British Medical Journal. 2010; 340:c2115. crossref PMid:20483950

  • Piddock LJV. The crisis of no new antibiotics- what is the way forward? Lancet Infect Dis. 2012; 12:249–53. crossref

  • Shallcross LJ, Davies SC. The World Health Assembly resolution on antimicrobial resistance. J Antimicrob Chemother. 2014; 69(11):2883–5. crossref PMid:25204342

  • Cecchini M, Langer J, Slawomirski L. Antimicrobial resistance in G7 countries and beyond: Economic issues, policies and options for action. 2015 Sep. Available from: crossref

  • Smith RD, Yago M, Millar M, Coast J. A macroeconomic approach to evaluating policies to contain

  • antimicrobial resistance: A case study of methicillin-resistant Staphylococcus aureus (MRSA). Appl Health Econ Health Policy. 2006; 5(1):55–65. crossref PMid:16774293

  • World Health Organisation. Global framework for development & stewardship to combat antimicrobial resistance. Geneva: WHO; 2017. Available from: crossref implementation/ research/WHA_BackgroundPaper-AGlobal FrameworkDevelopment Stewardship-Version2.pdf?ua=1

  • Review on antimicrobial resistance. Antimicrobial resistance: Tackling a crisis for the health and wealth of nations. London: Review on AMR, Welcome Trust, HM Government; 2014.

  • Chandler CIR, Hutchinson E, Hutchison C. addressing antimicrobial resistance through social theory: An anthropologically oriented report. London School of Hygiene & Tropical Medicine; 2016. Available from: crossref

  • Ozrech KM, Nichter M. From resilience to resistance: political ecological lessons from antibiotic and pesticide resistance. Annual Review of Anthropology. 2008; 37:267–82. crossref

  • Out of pocket payments by medical scheme members: Research and Monitoring. 2015. Available from: crossref

  • Centers for disease control and prevention. Office of infectious disease: Antibiotic resistance threats in the United States; 2013. Available from: crossref

  • World Health Organisation. The evolving threat of antimicrobial resistance Options for action. Geneva: World Health Organization; 2012. Available from: crossref

  • ECDC and EMEA. The bacterial challenge. Time to react, ECDC/EMEA Joint Technical Report. European centre for disease prevention and control. Stockholm; 2009. Available from: crossref

  • Tyrie K, Wohl D, Curry W. Effects of antibiotic exposure and immune system challenge on the development of allergic asthma. Bios. 2013; 84(1):14–20. crossref

  • Cohen B, Larson EL, Stone PW, Neidell M, Glied SA. Factors associated with variation in estimates of the cost of resistant infections. Med Care. 2010; 48(9):767–75. crossref PMid:20706168 PMCid:PMC2924922

  • Sipahi, OR. Economics of antibiotic resistance. Expert Review of Anti-Infective Therapy. 2008; 6(4):523–39. crossref PMid:18662118

  • Smith RD, Coast J. The economic burden of antimicrobial resistance: Why it is more serious than current studies suggest [Technical Report]. London: London School of Hygiene & Tropical Medicine; 2012. Available from: crossref

  • Tansarli GS, Karageorgopoulos DE, Kapaskelis A, Falagas ME. Impact of antimicrobial multidrug resistance on inpatient care cost: An evaluation of the evidence. Expert Review of Anti-Infective Therapy. 2013; 11(3):321–31. crossref PMid:23458771

  • World Health Organisation. Antimicrobial resistance: global report on surveillance. Geneva: WHO; 2014.

  • Available from: crossref

  • Cosgrove SE. The relationship between antimicrobial resistance and patient outcomes: Mortality, length of hospital stay, and health care costs. Clin Infect Dis. 2006; 42(2):S82–9. crossref PMid:16355321

  • McNulty CA, Lasseter GM, Charlett A, Lovering A, Howell-Jones R, Macgowan A, et al. Does laboratory antibiotic susceptibility reporting influence primary care prescribing in urinary tract infection and other infections? J Antimicrob Chemother. 2011; 66(6):1396–404. crossref PMid:21398297

  • Spellberg B, Guidos R, Gilbert D, Bradley J, Boucher HW, Scheld WM, et al. The epidemic of antibiotic-resistant infections: A call to action for the medical community from the Infectious Diseases Society of America. Clinical Infectious Diseases. 2008; 46(2):155–64. crossref PMid:18171244

  • Jonasa, Olga B. Pandemic Risk. World Bank, Washington, DC: World Bank; 2013. Available from: crossref

  • FAO. Food and Agriculture Organisation of the United Nation; 2010. Available from: crossref

  • FAO Resolution 4/2015. Available from: crossref

  • OIE Resolution No. 26; 2015. Available from: crossref

  • World Health Organisation. Monitoring the building blocks of health systems: A Handbook of indicators and their measurement strategies. Geneva: World Health Organisation; 2010. Available from: crossref

  • World Health Organisation. What is health policy and systems research and why does it matter? Geneva: Alliance for Health Policy and Systems Research; 2007. Available from: crossref

  • World Health Organisation, Europe. 9th Futures Forum on health systems governance and public participation. Denmark: WHO Regional Office, Europe; 2006.

  • Lavis JN, Ross SE, Hurley JE, et al. Examining the role of health services research in public policymaking. Milbank Q. 2002; 80:125–54. crossref PMid:11933791 PMCid:PMC2690103

  • Grol R, Grimshaw J. From best evidence to best practice: effective implementation of change in patients’ care. Lancet. 2003; 362:1225–30. crossref

  • Haines A, Kuruvilla S, Borchert M. Bridging the implementation gap between knowledge and action for

  • health. Bull World Health Organ. 2004; 82:724–31. PMid:15643791 PMCid:PMC2623035

  • Adams JS. Inequity in social change. Berkowitz L, editor. Advances in experimental social psychology New York: Academic Press; 1965. p. 267–99.

  • Cropanzano R, Greenberg J. Progress in organizational justice: Tunneling through the maze. Cooper CL, Robertson IT, editors. International Review of Industrial and Organizational Psychology. New York: Wiley; 1997. p. 317–72.

  • Olafsen AH, Halvari H, Forest J, Deci EL. Show them the money? The role of pay, managerial needs support, and justice in a self‐determination theory model of intrinsic work motivation. Scandinavian journal of psychology. 2015; 56(4):447–57. crossref PMid:25810152

  • Gagne M, Deci EL. Self-determination theory and work motivation. Journal of organizational Behavior. 2005; 26(4):331–62. crossref

  • Department of Health. Minister Aaron Motsoaledi: Health Dept Budget Vote 2017/18. DOH, Republic of South Africa; 2016. Available from: crossref

  • Statistics South Africa. People. South Africa; 2011. Available from: crossref

  • World Economic Forum. The Global Economic Burden of Non-communicable Diseases. Harvard School of Public Health, World Economic Forum; 2011. Available from: crossref

  • Howard D, Cordell R, Mcgowan JE, Packard RM, Scott RD, Solomon SL. Measuring the economic costs of antimicrobial resistance in hospital settings: Summary of the centers for disease control and prevention-emory workshop. Clin Infect Dis. 2001; 33(9):1573–8. crossref PMid:11577379

  • Health Department of National Health Insurance in South Africa Policy Paper; 2011. Available from: crossref

  • World Health Organisation. The Abuja Declaration: Ten years on. Geneva: World Health Organisation; 2001. Available from: crossref

  • Hugo J. Health workers in South Africa not an easy option. Department of Health. Health Systems Trust. Available from: crossref

  • Winters C, Gelband H. The Global Antibiotic Resistance Partnership (GARP). South African Medical Journal. 2011; 101(8):556–7. PMid:21920132

  • World Health Organisation. Media centre: Global health workforce shortage to reach 12.9 million in coming decades. Geneva: WHO; 2013. Available from: crossref

  • Dodani S, LaPorte RE. Brain drain from developing countries: how can brain drain be converted into wisdom gain?. J R Soc Med. 2005; 98(11):487–491. crossref PMid:16260795 PMCid:PMC1275994

  • World Health Organisation. International Migration of Health Workers. Improving international co-operation to address the Global Health Workforce Crisis. France: OECD; 2010. Available from: crossref

  • World Health Organization. Global Health Observatory. Geneva: WHO; 2017. Available from: crossref

  • World Health Organization. Global Health Observatory. Geneva: WHO; 2017. Available from: crossref

  • World Health Organization. Global Health Observatory. Geneva: WHO; 2017. Available from: crossref

  • International Pharmaceutical Federation. 2012 FIP global Pharmacy: Work force report. FIP. The Netherlands; 2012. Available from: crossref

  • Health System Trust. South Africas chronic shortage of health care professionals. Available from: crossref

  • World Health Organisation. HIV/AIDS Programme. Taking stock: Health worker shortages and the response to AIDS. Geneva: WHO; Available from: crossref

  • Tsolekile LP, Abrahams-Gessel S, Puoane T. healthcare professional shortage and task-shifting to prevent cardiovascular disease: Implications for low- and middle-income Countries. Curr Cardiol Rep. 2015; 17(12):115. crossref PMid:26482758

  • Bertino JS. Cost burden of viral respiratory infections: issues for formulary decision makers. Am J Med. 2002; 112(6):42–9. crossref

  • World Health Organisation. Treat, Train and Retain: HIV/AIDS; Task Shifting: Global Recommendations and Guidelines. Geneva: WHO; 2008. crossref

  • Ferrinho P, Sidat. M, Goma F, Dussault G. Task-shifting: Experiences and opinions of health workers in Mozambique and Zambia. Human Resources for Health. 2012; 10:34. crossref PMid:22985229 PMCid:PMC3515799

  • Baine SO, Kasangaki A. A scoping study on task shifting: The case of Uganda. BMC Health Services Research. 2014; 14:184. crossref PMid:24754917 PMCid:PMC4036592

  • Berman PA, Gwatkin DR, Burger SE. Community-based health workers: head start or false start towards health for all? Soc Sci Med. 1987; 25(5):443–59. crossref

  • Gilmore B, Adams B J, Bartoloni A, Alhaydar B, McAuliffe E, Raven J, et al. Improving the performance of community health workers in humanitarian emergencies: A realist evaluation protocol for the PIECES programme. BMJ Open. 2016; 6:e011753. crossref PMid:27531730 PMCid:PMC5013374

  • Campbell C, Scott K. Retreat from Alma Ata? The WHO’s report on task shifting to community health workers for AIDS care in poor countries. Global Public Health. 2011; 6(2):125–38. crossref PMid:19916089

  • World Health Organisation. Community health workers: What do we know about them? The state of the evidence on programmes, activities, costs and impact on health outcomes of using community health workers. Geneva: WHO; 2007. Available from: crossref

  • World Health Organisation. Global Experience of Community Health Workers for Delivery of Health Related Millennium Development Goals: A Systematic Review, Country Case Studies, and Recommendations for Integration into National Health Systems, Geneva: WHO; 2010. Available from: crossref

  • Chokshi DA. Improving access to medicines in poor countries: The role of universities. PLoS Med. 2006; 3(6):e136. crossref PMid:16608382 PMCid:PMC1435781

  • Ahuja R. Unlocking the floodgates: A novel strategy to pass soda taxes. Young Professionals Chronic Disease Network (YP-CDN); 2016. Available from: crossref

  • Jarvis JD, Obscherning E, Siegel K, Kishore SP. A global social network to catalyze solutions for chronic NCD a case study on the young professionals chronic disease network. Global Heart. 2016; 11(4):463–5. crossref PMid:27938843

  • South African Government. Youth Day. Republic of South Africa, 2016 Jun; Available from: crossref


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  • Leadership and Task Shifting to Address the Challenges of Antimicrobial Resistance in South Africa

Abstract Views: 490  |  PDF Views: 185

Authors

Kemesha Govender
Rhodes University, Grahamstown, South Africa
Samridhi Sharma
Rhodes University, Grahamstown, South Africa
William Jessee
Ambulatory Pharmacy Services, Cleveland Clinic, Abu Dhabi, United Arab Emirates
Kiran Nagaraju
Department of Pharmacy Practice, Visveswarapura Institute of Pharmaceutical Sciences, Bengaluru, India
Noel J. Pearse
Rhodes Business School, Rhodes University, Grahamstown, South Africa
Pratik Chhetri
YP-CDN, United States
Elisa M. Bodenstab
Department of Anthropology, Rhodes University, Grahamstown, South Africa
Pei Yu
College of Pharmacy, Jinan University, Guangzhou, China
Sunitha C. Srinivas
Rhodes University, Grahamstown, South Africa

Abstract


Antimicrobial resistance is a complex problem interconnected with many factors, such as overuse and misuse of antimicrobials across the world, especially in Low- and Middle-Income Countries (LMICs). To overcome this, the Global Action Plan requires commitment action in LMICs, aimed at education and health promotion to all. Demand for the Health Care Professionals (HCPs) in developed countries and exponential chances of earning had led to the shortage of HCPs in most countries and severe shortage in more than 50 LMICs. Community Health Workers (CHWs) are being recognised in many LMICs to deliver primary health care service with minimum training as an alternative solution to combat the situation, which can improve the cost-effectiveness of health care systems. These CHWs can reach large number of people in the community where the public sector provided health service is very minimal and private health care sector is unaffordable.

Keywords


Antimicrobial Agents, Antimicrobial Resistance, Community Health Workers, Leadership, Task Shifting, World Health Organisation, Youth Empowerment.

References





DOI: https://doi.org/10.18311/ajprhc%2F2018%2F16265