Asian Journal of Pharmaceutical Research and Health Care

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Early Outcomes of Transoral Laser Microsurgery for T1-T2 Oropharyngeal Cancer


Affiliations
1 School of Medicine, Vietnam National University - Ho Chi Minh City, Linh Trung Ward, Thu Duc District, Ho Chi Minh City - 700000, Viet Nam
 

The optimal treatment strategy for oropharyngeal carcinoma is highly debated. However, growing evidence supports the use of minimally invasive techniques, such as Transoral Laser Microsurgery (TLM), as a first-line treatment modality for these carcinomas. The purpose of our study was to assess the efficacy and safety of TLM for the treatment of early oropharyngeal carcinomas. This is a prospectively observational study of 30 early stages (T1/T2) oropharyngeal cancer patients who underwent transoral laser microsurgery from January 2016 to March 2019. 30 patients of early-staged oropharyngeal carcinoma (19 tongues, 5 soft palates, 4 tonsils and 2 posterior pharyngeal walls) were included in this study. 19 (63.3%) patients were male and 11 (36.7%) were female. The mean age was 54.8 years (± 10.6 years). 76.7% tumours are T1 and 23.3% T2. The bleeding complications occurred in 2 patients. The most frequent complication of TLM was bleeding. 30% of patients had normal voices and a further 63.3% had only mild or moderate voice change. At their last follow up, no patients had any difficulty in breathing or swallowing. TLM is a safe, minimally invasive and effective method in the treatment for early oropharyngeal cancer.

Keywords

Carbon Dioxide Laser, Oropharyngeal Carcinoma, Transoral Laser Microsurgery.
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  • Early Outcomes of Transoral Laser Microsurgery for T1-T2 Oropharyngeal Cancer

Abstract Views: 421  |  PDF Views: 236

Authors

Tran Phan Chung Thuy
School of Medicine, Vietnam National University - Ho Chi Minh City, Linh Trung Ward, Thu Duc District, Ho Chi Minh City - 700000, Viet Nam
Nguyen Thanh Tuan
School of Medicine, Vietnam National University - Ho Chi Minh City, Linh Trung Ward, Thu Duc District, Ho Chi Minh City - 700000, Viet Nam

Abstract


The optimal treatment strategy for oropharyngeal carcinoma is highly debated. However, growing evidence supports the use of minimally invasive techniques, such as Transoral Laser Microsurgery (TLM), as a first-line treatment modality for these carcinomas. The purpose of our study was to assess the efficacy and safety of TLM for the treatment of early oropharyngeal carcinomas. This is a prospectively observational study of 30 early stages (T1/T2) oropharyngeal cancer patients who underwent transoral laser microsurgery from January 2016 to March 2019. 30 patients of early-staged oropharyngeal carcinoma (19 tongues, 5 soft palates, 4 tonsils and 2 posterior pharyngeal walls) were included in this study. 19 (63.3%) patients were male and 11 (36.7%) were female. The mean age was 54.8 years (± 10.6 years). 76.7% tumours are T1 and 23.3% T2. The bleeding complications occurred in 2 patients. The most frequent complication of TLM was bleeding. 30% of patients had normal voices and a further 63.3% had only mild or moderate voice change. At their last follow up, no patients had any difficulty in breathing or swallowing. TLM is a safe, minimally invasive and effective method in the treatment for early oropharyngeal cancer.

Keywords


Carbon Dioxide Laser, Oropharyngeal Carcinoma, Transoral Laser Microsurgery.

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DOI: https://doi.org/10.18311/ajprhc%2F2018%2F23526