Protective Effect on Hygrophila auriculata Leaf Extraction Cadmium Chloride Induced Hepatotoxicity in Albino Wistar Rats

Protective effect of Hygrophila auriculata leaf extract on cadmium chloride induced hepatotoxicity in albino wistar rats were investigated by analyzing various biochemical parameters. cadmium chloride induced hepatic damage was well manifested by significant increase in the activities of SGOT, SGPT, ALP, ACP, total bilirubin, MDA and LDH and also decreased in total protein and GSH. The oral administration of aqueous extract of Hygrophila auriculata (100mg/kg body wight) along with cadmium chloride for 7 days reversed these altered parameters to normal level which indicating the hepatoprotective efficacy of Hygrophila auriculata against cadmium chloride induced liver injury. Phytochemical constituents such as flavonoids are responsible for the hepato protective activity of Hygrophila auriculata. Further extensive studies are required for its potential uses in clinical practice.