Asian Journal of Bio Science

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Studies on Antioxidant and Anthelmintic Activity of Gnidia glauca (Fresen) Gilg.


Affiliations
1 Department of Studies and Research in Microbiology, P.G. Institute of Studies and Research in Microbiology, Kuvempu University, Jnanasahyadri, Shankaraghatta (Karnataka), India
2 Department of Microbiology, S.R.N.M.N. College of Applied Sciences, NES Campus, Shivamogga (Karnataka), India
3 Department of Studies and Research in Applied Botany, Kuvempu University, Jnanasahyadri, Shankaraghatta (Karnataka), India
4 Department of Studies and Research in Microbiology, Kuvempu University, Shivagangothri, Tholahunase, Davangere (Karnataka), India
     

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The present study was carried to evaluate antioxidant and anthelmintic activity of methanol, chloroform, ethyl acetate, acetone and petroleum ether extracts of Gnidia glauca (Fresen) Gilg. The preliminary phytochemical tests showed the presence of tannins, terpenoids, steroids, saponins and flavonoids. A dose dependent antioxidant activity was observed in case of extracts. Methanol extract was found to possess greater radical scavenging potential than other extracts. All extracts were found to cause paralysis and death of worms but not to the extent of standard drug. Among extracts tested, the acetone extract took less time to cause paralysis and death of the worms when compared to other extracts. The antioxidant and anthelmintic activity of the solvent extracts could be mainly due to the presence of various phytoconstituents. Further studies are to be conducted to isolate active constituents and to find out the in vivo efficacy of the plant extracts tested.

Keywords

Gnidia glauca (Fresen) Glig.,antioxidant Activity, DPPH Assay, Anthelmintic Activity, Pheretima Pasthuma.
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  • Studies on Antioxidant and Anthelmintic Activity of Gnidia glauca (Fresen) Gilg.

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Authors

H. R. Nethravathi
Department of Studies and Research in Microbiology, P.G. Institute of Studies and Research in Microbiology, Kuvempu University, Jnanasahyadri, Shankaraghatta (Karnataka), India
T. R. Prashith Kekuda
Department of Microbiology, S.R.N.M.N. College of Applied Sciences, NES Campus, Shivamogga (Karnataka), India
K. S. Vinayaka
Department of Studies and Research in Applied Botany, Kuvempu University, Jnanasahyadri, Shankaraghatta (Karnataka), India
N. B. Thippeswamy
Department of Studies and Research in Microbiology, P.G. Institute of Studies and Research in Microbiology, Kuvempu University, Jnanasahyadri, Shankaraghatta (Karnataka), India
S. J. Sudharshan
Department of Microbiology, S.R.N.M.N. College of Applied Sciences, NES Campus, Shivamogga (Karnataka), India
S. V. Praveen Kumar
Department of Studies and Research in Microbiology, Kuvempu University, Shivagangothri, Tholahunase, Davangere (Karnataka), India

Abstract


The present study was carried to evaluate antioxidant and anthelmintic activity of methanol, chloroform, ethyl acetate, acetone and petroleum ether extracts of Gnidia glauca (Fresen) Gilg. The preliminary phytochemical tests showed the presence of tannins, terpenoids, steroids, saponins and flavonoids. A dose dependent antioxidant activity was observed in case of extracts. Methanol extract was found to possess greater radical scavenging potential than other extracts. All extracts were found to cause paralysis and death of worms but not to the extent of standard drug. Among extracts tested, the acetone extract took less time to cause paralysis and death of the worms when compared to other extracts. The antioxidant and anthelmintic activity of the solvent extracts could be mainly due to the presence of various phytoconstituents. Further studies are to be conducted to isolate active constituents and to find out the in vivo efficacy of the plant extracts tested.

Keywords


Gnidia glauca (Fresen) Glig.,antioxidant Activity, DPPH Assay, Anthelmintic Activity, Pheretima Pasthuma.