Asian Journal of Bio Science

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Screening and Characterization of Ethnopharmacological Properties of Selected Flowers and Spices Against Candida albicans


Affiliations
1 Postgraduate and Research Department of Microbiology, Dr.N.G.P.Arts and Science College, Coimbatore (T.N.), India
2 Postgraduate and Research Department of Biotechnology, Dr.N.G.P.Arts and Science College, Coimbatore (T.N.), India
     

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60 pus samples collected from Coimbatore Medical College (CMC) were processed for the isolation of Candida albicans, among which 24 (40%) were found to be positive. Anticandidal susceptibility pattern revealed that the strains were highly sensitive to fluconazole, ketoconazole; moderately sensitive to clotrimazole and but resistant to nystatin. When the same strains were evaluated for their susceptibility towards aqueous and diethyl ether herbal extracts from Allium sativum, Punica granatum, Syzium aromaticum and Cassia auriculata the results were interesting that they are highly sensitive. The maximum inhibition was found to be 49 mm with Punica granatum followed by 29mm with Allium sativum. The GC-MS analysis of both the extracts revealed the bioactive principles responsible for anticandidal activity.

Keywords

Allium sativum, Punica granatum, Syzium aromaticum, Cassia auriculata, Candida albicans.
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  • Screening and Characterization of Ethnopharmacological Properties of Selected Flowers and Spices Against Candida albicans

Abstract Views: 263  |  PDF Views: 0

Authors

R. Anand
Postgraduate and Research Department of Microbiology, Dr.N.G.P.Arts and Science College, Coimbatore (T.N.), India
E. Saritha
Postgraduate and Research Department of Biotechnology, Dr.N.G.P.Arts and Science College, Coimbatore (T.N.), India
R. Aswini
Postgraduate and Research Department of Microbiology, Dr.N.G.P.Arts and Science College, Coimbatore (T.N.), India
V. H. Mary Jiji
Postgraduate and Research Department of Microbiology, Dr.N.G.P.Arts and Science College, Coimbatore (T.N.), India

Abstract


60 pus samples collected from Coimbatore Medical College (CMC) were processed for the isolation of Candida albicans, among which 24 (40%) were found to be positive. Anticandidal susceptibility pattern revealed that the strains were highly sensitive to fluconazole, ketoconazole; moderately sensitive to clotrimazole and but resistant to nystatin. When the same strains were evaluated for their susceptibility towards aqueous and diethyl ether herbal extracts from Allium sativum, Punica granatum, Syzium aromaticum and Cassia auriculata the results were interesting that they are highly sensitive. The maximum inhibition was found to be 49 mm with Punica granatum followed by 29mm with Allium sativum. The GC-MS analysis of both the extracts revealed the bioactive principles responsible for anticandidal activity.

Keywords


Allium sativum, Punica granatum, Syzium aromaticum, Cassia auriculata, Candida albicans.